ES2513516T3 - Método para un sellado con fibrina mejorado - Google Patents

Método para un sellado con fibrina mejorado Download PDF

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Publication number
ES2513516T3
ES2513516T3 ES11706629.0T ES11706629T ES2513516T3 ES 2513516 T3 ES2513516 T3 ES 2513516T3 ES 11706629 T ES11706629 T ES 11706629T ES 2513516 T3 ES2513516 T3 ES 2513516T3
Authority
ES
Spain
Prior art keywords
improved fibrin
effective amount
fibrin sealing
sealing
wet tissue
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES11706629.0T
Other languages
English (en)
Spanish (es)
Inventor
Erez Ilan
Israel Nur
Kfir Regev
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Omrix Biopharmaceuticals Ltd
Original Assignee
Omrix Biopharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Omrix Biopharmaceuticals Ltd filed Critical Omrix Biopharmaceuticals Ltd
Application granted granted Critical
Publication of ES2513516T3 publication Critical patent/ES2513516T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/043Mixtures of macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001Use of materials characterised by their function or physical properties
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001Use of materials characterised by their function or physical properties
    • A61L24/0015Medicaments; Biocides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001Use of materials characterised by their function or physical properties
    • A61L24/0042Materials resorbable by the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/0047Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/10Polypeptides; Proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/10Polypeptides; Proteins
    • A61L24/106Fibrin; Fibrinogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D81/00Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
    • B65D81/32Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents for packaging two or more different materials which must be maintained separate prior to use in admixture
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/252Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/252Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
    • A61L2300/254Enzymes, proenzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/418Agents promoting blood coagulation, blood-clotting agents, embolising agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/45Mixtures of two or more drugs, e.g. synergistic mixtures
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/606Coatings
    • A61L2300/608Coatings having two or more layers
    • A61L2300/61Coatings having two or more layers containing two or more active agents in different layers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00Materials characterised by their function or physical properties
    • A61L2400/04Materials for stopping bleeding

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mechanical Engineering (AREA)
  • Composite Materials (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ES11706629.0T 2010-01-28 2011-01-27 Método para un sellado con fibrina mejorado Active ES2513516T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US29912710P 2010-01-28 2010-01-28
US299127P 2010-01-28
PCT/IL2011/000092 WO2011092694A2 (en) 2010-01-28 2011-01-27 Method for improved fibrin sealing

Publications (1)

Publication Number Publication Date
ES2513516T3 true ES2513516T3 (es) 2014-10-27

Family

ID=43923707

Family Applications (1)

Application Number Title Priority Date Filing Date
ES11706629.0T Active ES2513516T3 (es) 2010-01-28 2011-01-27 Método para un sellado con fibrina mejorado

Country Status (14)

Country Link
US (2) US8962033B2 (enExample)
EP (1) EP2528631B1 (enExample)
JP (1) JP5859461B2 (enExample)
KR (1) KR101786786B1 (enExample)
CN (1) CN102791299B (enExample)
AU (1) AU2011210356B2 (enExample)
BR (1) BR112012018970B1 (enExample)
CA (1) CA2787883C (enExample)
DK (1) DK2528631T3 (enExample)
ES (1) ES2513516T3 (enExample)
MX (1) MX2012008845A (enExample)
RU (1) RU2556960C2 (enExample)
WO (1) WO2011092694A2 (enExample)
ZA (1) ZA201206438B (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL234246A0 (en) * 2014-08-21 2014-11-30 Omrix Biopharmaceuticals Ltd Stabilized thrombin
CA2960589A1 (en) 2014-09-11 2016-03-17 Omrix Biopharmaceuticals Ltd. Addition to a medical applicator
US9801983B2 (en) * 2014-12-18 2017-10-31 Cook Medical Technologies Llc Medical devices for delivering a bioactive to a point of treatment and methods of making medical devices
US20170128617A1 (en) * 2015-11-11 2017-05-11 Ethicon, Inc. Sealant formulation and uses thereof
IL247821A0 (en) 2016-09-14 2017-01-31 Omrix Biopharmaceuticals Ltd Adhesive preparations and their use
US12115356B2 (en) * 2019-03-06 2024-10-15 Gambro Lundia Ab Device and method for the delivery of a thrombin activated fibrin sealant
KR102093839B1 (ko) * 2019-05-28 2020-05-04 (주)다림티센 지혈용 조성물 및 이를 포함하는 용기
US11666682B2 (en) * 2020-08-31 2023-06-06 Ethicon, Inc. Method of stopping CSF leaks and apparatus therefor

Family Cites Families (34)

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Publication number Priority date Publication date Assignee Title
US1776489A (en) 1928-03-12 1930-09-23 Carolus M Cobb Powder distributor
ATE20824T1 (de) * 1981-06-25 1986-08-15 Serapharm Gmbh & Co Kg Angereichertes plasmaderivat zur unterstuetzung von wundverschluss und wundheilung.
AT379311B (de) 1984-03-29 1985-12-27 Immuno Ag Vorrichtung zur applikation eines gewebeklebstoffes
DE3725552A1 (de) 1987-08-01 1989-02-09 Hoechst Ag Spruehkopf zum applizieren eines mehrkomponentenmaterials mittels gas
DE3843126C3 (de) 1988-12-22 1994-10-06 Octapharma Ag Verfahren zur Herstellung eines hochreinen Thrombinkonzentrates
US5116315A (en) 1989-10-03 1992-05-26 Hemaedics, Inc. Biological syringe system
US7208179B1 (en) 1990-11-27 2007-04-24 The American National Red Cross Methods for treating disease and forming a supplemented fibrin matrix
US5690675A (en) 1991-02-13 1997-11-25 Fusion Medical Technologies, Inc. Methods for sealing of staples and other fasteners in tissue
US5792835A (en) 1991-09-05 1998-08-11 Baxter International Inc. Method of preparing a topical fibrinogen complex
WO1993005822A1 (en) 1991-09-27 1993-04-01 Octapharma Ag Tissue glue prepared by using cryoprecipitate
WO1994007420A1 (fr) 1992-09-26 1994-04-14 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute Applicateur d'adhesif destine a des tissus
CN1088117A (zh) * 1992-12-14 1994-06-22 白求恩医科大学第二临床学院 高效生物胶
US5330974A (en) * 1993-03-01 1994-07-19 Fibratek, Inc. Therapeutic fibrinogen compositions
AT400304B (de) 1994-02-28 1995-12-27 Immuno Ag Vorrichtung zur applikation eines mehrkomponenten-gewebeklebstoffes
WO1996022115A1 (en) 1995-01-16 1996-07-25 Baxter International Inc. Self-supporting sheet-like material of cross-linked fibrin for preventing post operative adhesions
AU708165B2 (en) 1995-06-06 1999-07-29 Interpore International Inc. Wound sealant preparation and application device and method
DE19521324C1 (de) 1995-06-12 1996-10-31 Immuno Ag Gewebeklebstoff und Verwendung desselben als Hämostyptikum
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US6121232A (en) 1997-01-31 2000-09-19 Omrix Biopharmaceuticals Sa Stabilized mixture comprising fibrinogen
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DE19849589C1 (de) 1998-10-27 2000-06-15 Glatt Process Technology Gmbh Fibrin-Gewebekleber-Formulierung und Verfahren zu dessen Herstellung
ATA49899A (de) 1999-03-19 2002-06-15 Immuno Ag Verfahren und vorrichtung zum mischen von komponenten
US20050049178A1 (en) * 1999-07-06 2005-03-03 Oberschwabenklinik Gmbh Agent for the occlusion of blood vessels
US6802822B1 (en) 2000-03-31 2004-10-12 3M Innovative Properties Company Dispenser for an adhesive tissue sealant having a flexible link
US6585696B2 (en) 2000-12-22 2003-07-01 Baxter International, Inc. Method and apparatus for applying a medically useful multiple component material
BRPI0206708B8 (pt) 2001-01-25 2021-06-22 Nycomed Pharma As composição sólida, composição para hemostasia, vedação de tecido e colagem de tecido, e, usos de um veículo de colágeno
PL205685B1 (pl) 2001-05-21 2010-05-31 Omrix Biopharm Sa Sposób in vitro usuwania lub wyodrębniania plazminogenu lub plazminy w obecności fibrynogenu, stałe podłoże powinowactwa do oczyszczania mieszaniny zawierającej fibrynogen i plazminę i/lub plazminogen oraz krioprecypitat
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DE602005013301D1 (de) 2005-11-22 2009-04-23 Omrix Biopharm Sa Applikatorvorrichtung zum aufbringen einer mehrkomponenten-flüssigkeit
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EP2011524A1 (en) 2007-07-02 2009-01-07 Omrix Biopharmaceuticals Ltd. Fibrin glue with a visualization agent
JP5805542B2 (ja) 2009-02-20 2015-11-04 オムリックス・バイオファーマシューティカルズ・リミテッドOmrix Biopharmaceuticals Ltd. 少なくとも2成分の薬物を投与する装置

Also Published As

Publication number Publication date
EP2528631A2 (en) 2012-12-05
WO2011092694A3 (en) 2011-09-29
CA2787883A1 (en) 2011-08-04
DK2528631T3 (da) 2014-09-15
AU2011210356B2 (en) 2015-05-28
CA2787883C (en) 2019-02-19
US8962033B2 (en) 2015-02-24
RU2556960C2 (ru) 2015-07-20
CN102791299A (zh) 2012-11-21
KR20120128132A (ko) 2012-11-26
CN102791299B (zh) 2014-10-22
ZA201206438B (en) 2014-01-29
MX2012008845A (es) 2012-09-28
BR112012018970B1 (pt) 2018-10-30
AU2011210356A1 (en) 2012-08-23
US9302026B2 (en) 2016-04-05
JP5859461B2 (ja) 2016-02-10
EP2528631B1 (en) 2014-08-06
WO2011092694A8 (en) 2012-12-13
US20150125440A1 (en) 2015-05-07
KR101786786B1 (ko) 2017-10-18
RU2012136648A (ru) 2014-03-10
JP2013517886A (ja) 2013-05-20
US20110182991A1 (en) 2011-07-28
WO2011092694A2 (en) 2011-08-04
BR112012018970A2 (pt) 2017-10-10

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