ES249507A1 - Un método para la preparacion de un compuesto de amonio cuaternario - Google Patents
Un método para la preparacion de un compuesto de amonio cuaternarioInfo
- Publication number
- ES249507A1 ES249507A1 ES0249507A ES249507A ES249507A1 ES 249507 A1 ES249507 A1 ES 249507A1 ES 0249507 A ES0249507 A ES 0249507A ES 249507 A ES249507 A ES 249507A ES 249507 A1 ES249507 A1 ES 249507A1
- Authority
- ES
- Spain
- Prior art keywords
- group
- ethyl
- bromobenzyl
- prepared
- quaternary ammonium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000003856 quaternary ammonium compounds Chemical class 0.000 title abstract 4
- 238000002360 preparation method Methods 0.000 title abstract 2
- 125000000954 2-hydroxyethyl group Chemical group [H]C([*])([H])C([H])([H])O[H] 0.000 abstract 4
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 4
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 4
- 125000002112 pyrrolidino group Chemical group [*]N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H] 0.000 abstract 3
- -1 1,4-disubstituted butane Chemical class 0.000 abstract 2
- 125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 abstract 2
- 150000001768 cations Chemical class 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 abstract 2
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 2
- 239000000725 suspension Substances 0.000 abstract 2
- 150000003512 tertiary amines Chemical class 0.000 abstract 2
- RWRDLPDLKQPQOW-UHFFFAOYSA-N tetrahydropyrrole Natural products C1CCNC1 RWRDLPDLKQPQOW-UHFFFAOYSA-N 0.000 abstract 2
- IOWGHQGLUMEZKG-UHFFFAOYSA-N (2-bromophenyl)methanol Chemical compound OCC1=CC=CC=C1Br IOWGHQGLUMEZKG-UHFFFAOYSA-N 0.000 abstract 1
- LMPCMAVLCWQDRJ-UHFFFAOYSA-N (2-bromophenyl)methyl 4-methylbenzenesulfonate Chemical compound C1=CC(C)=CC=C1S(=O)(=O)OCC1=CC=CC=C1Br LMPCMAVLCWQDRJ-UHFFFAOYSA-N 0.000 abstract 1
- CJAAPVQEZPAQNI-UHFFFAOYSA-N (2-methylphenyl)methanamine Chemical compound CC1=CC=CC=C1CN CJAAPVQEZPAQNI-UHFFFAOYSA-N 0.000 abstract 1
- ZPZPSZZVDFMNQS-UHFFFAOYSA-N 1-(2-bromophenyl)-n,n-dimethylmethanamine Chemical compound CN(C)CC1=CC=CC=C1Br ZPZPSZZVDFMNQS-UHFFFAOYSA-N 0.000 abstract 1
- NSCATPOHERQCFD-UHFFFAOYSA-N 1-(2-fluorophenyl)-n,n-dimethylmethanamine Chemical compound CN(C)CC1=CC=CC=C1F NSCATPOHERQCFD-UHFFFAOYSA-N 0.000 abstract 1
- XIUPKYDFTUADKF-UHFFFAOYSA-N 1-[(2-chlorophenyl)methyl]pyrrolidine Chemical compound ClC1=CC=CC=C1CN1CCCC1 XIUPKYDFTUADKF-UHFFFAOYSA-N 0.000 abstract 1
- LZSYGJNFCREHMD-UHFFFAOYSA-N 1-bromo-2-(bromomethyl)benzene Chemical compound BrCC1=CC=CC=C1Br LZSYGJNFCREHMD-UHFFFAOYSA-N 0.000 abstract 1
- BASMANVIUSSIIM-UHFFFAOYSA-N 1-chloro-2-(chloromethyl)benzene Chemical compound ClCC1=CC=CC=C1Cl BASMANVIUSSIIM-UHFFFAOYSA-N 0.000 abstract 1
- RMILXCMZOMROKB-UHFFFAOYSA-N 2-[(2-methylphenyl)methylamino]ethanol Chemical compound CC1=CC=CC=C1CNCCO RMILXCMZOMROKB-UHFFFAOYSA-N 0.000 abstract 1
- PVNNOLUAMRODAC-UHFFFAOYSA-N 4-(ethylamino)butan-1-ol Chemical compound CCNCCCCO PVNNOLUAMRODAC-UHFFFAOYSA-N 0.000 abstract 1
- XTHWKJOWZROZAP-UHFFFAOYSA-N 4-[(2-bromophenyl)methyl-ethylamino]butan-1-ol Chemical compound BrC1=C(CN(CCCCO)CC)C=CC=C1 XTHWKJOWZROZAP-UHFFFAOYSA-N 0.000 abstract 1
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 abstract 1
- UKTMQVFFIPGRDU-UHFFFAOYSA-N N-[(2-bromophenyl)methyl]-N-ethyl-4-iodobutan-1-amine hydroiodide Chemical compound I.BrC1=C(CN(CCCCI)CC)C=CC=C1 UKTMQVFFIPGRDU-UHFFFAOYSA-N 0.000 abstract 1
- AHVYPIQETPWLSZ-UHFFFAOYSA-N N-methyl-pyrrolidine Natural products CN1CC=CC1 AHVYPIQETPWLSZ-UHFFFAOYSA-N 0.000 abstract 1
- 125000004429 atom Chemical group 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000009833 condensation Methods 0.000 abstract 1
- 230000005494 condensation Effects 0.000 abstract 1
- 125000000118 dimethyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000002147 dimethylamino group Chemical group [H]C([H])([H])N(*)C([H])([H])[H] 0.000 abstract 1
- 239000008187 granular material Substances 0.000 abstract 1
- XMBWDFGMSWQBCA-UHFFFAOYSA-N hydrogen iodide Chemical compound I XMBWDFGMSWQBCA-UHFFFAOYSA-N 0.000 abstract 1
- JJWLVOIRVHMVIS-UHFFFAOYSA-N isopropylamine Chemical compound CC(C)N JJWLVOIRVHMVIS-UHFFFAOYSA-N 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- QUSNBJAOOMFDIB-UHFFFAOYSA-N monoethyl amine Natural products CCN QUSNBJAOOMFDIB-UHFFFAOYSA-N 0.000 abstract 1
- AHXJNCOFVXXIAS-UHFFFAOYSA-N n-[(2-chlorophenyl)methyl]propan-2-amine Chemical compound CC(C)NCC1=CC=CC=C1Cl AHXJNCOFVXXIAS-UHFFFAOYSA-N 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- BHRZNVHARXXAHW-UHFFFAOYSA-N sec-butylamine Chemical compound CCC(C)N BHRZNVHARXXAHW-UHFFFAOYSA-N 0.000 abstract 1
- 239000000829 suppository Substances 0.000 abstract 1
- 239000003826 tablet Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
- C07D295/073—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Un método para la preparación de un compuesto de amonio cuaternario que comprende una reacción de cuaternización caracterizado porque el compuesto de amonio cuaternario contiene un catión de la fórmula **(Ver fórmula)** donde X es un átomo de halógeno o un grupo metilo o nitro y R1 es un grupo etilo 2-hidroxietilo isopropilo o alilo cuando NR2R3 es un grupo dimetilamino o pirrolidino o R1 es un grupo metilo cuando R2 y R3 son iguales o diferentes y son grupos etilo o 2-hidroxietilo.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1896358A GB881265A (en) | 1958-06-13 | 1958-06-13 | Quaternary ammonium compounds and their preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES249507A1 true ES249507A1 (es) | 1959-10-01 |
Family
ID=10121446
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES0249507A Expired ES249507A1 (es) | 1958-06-13 | 1959-05-21 | Un método para la preparacion de un compuesto de amonio cuaternario |
Country Status (2)
| Country | Link |
|---|---|
| ES (1) | ES249507A1 (es) |
| GB (1) | GB881265A (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CZ2016117A3 (cs) * | 2016-02-29 | 2017-09-13 | Ústav makromolekulární chemie AV ČR, v. v. i. | Jodovaná radioznačitelná analoga cholinu, jejich příprava a použití jako léčiva |
| CN115260125A (zh) * | 2022-07-01 | 2022-11-01 | 青海百能汇通新能源科技有限公司 | 一种溴络合剂的合成工艺和装置 |
-
1958
- 1958-06-13 GB GB1896358A patent/GB881265A/en not_active Expired
-
1959
- 1959-05-21 ES ES0249507A patent/ES249507A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| GB881265A (en) | 1961-11-01 |
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