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AstraZeneca AB
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Astra AB
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Publication of ES247867A1publicationCriticalpatent/ES247867A1/en
A process for the preparation of compounds of the general formula ** (See formula) ** and physiologically harmless salts thereof, wherein G1 and G23 each represent ion element of the group consisting of oxygen and sulfur, R represents a hydrocarbon residue containing not more than 10 carbon atoms, preferably not more than 8; R1 and R2 each represent an atom or atomic group of the group consisting of hydrogen, low molecular weight alkyl and halogen; R3 and R4 each represent an atom or atomic group of the group consisting of hydrogen, methyl and ethyl, and R5 represents an atomic group of the group consisting of alicyclic and aliphatic residues of low molecular weight, including atomic groups that form together with one of the atomic groups R3 and R4 and an intermediate atom or atoms a heterocyclic ring, at most six members, with a heteroatom, at least and not more than 2, and n is 0 or 1, wherein the compounds of the general formulas ** (See formula) ** where V represents the group (see formula) or an atom or atomic group that can be transformed into it, x and y represent atoms or atomic groups capable of reacting with each other with formation of the bridge (see formula) between R and the aromatic nucleus, and Z and u represent atomic atoms or groups capable of reacting with each other with formation of the -NH-CO- (CH2) n bridge between the aromatic nucleus and V, they are reacted in such a way that a compound of the formula (I) is formed which, if desired, is converted into a salt. (Machine-translation by Google Translate, not legally binding)
ES0247867A1958-03-131959-03-12A procedure for the preparation of therapeutic compounds (Machine-translation by Google Translate, not legally binding)
ExpiredES247867A1
(en)
Procedure for preparing N-alcohilamino-alcohilic derivatives of espirotetralinosuccinimidas and their salts. (Machine-translation by Google Translate, not legally binding)
A procedure for the preparation of acil-anylides with basic substitutors and their derivatives (Machine-translation by Google Translate, not legally binding)