ES2477284T3 - Método de monitorización de la progresión de la enfermedad de Alzheimer por medición de un biomarcador - Google Patents
Método de monitorización de la progresión de la enfermedad de Alzheimer por medición de un biomarcador Download PDFInfo
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- ES2477284T3 ES2477284T3 ES10012836.2T ES10012836T ES2477284T3 ES 2477284 T3 ES2477284 T3 ES 2477284T3 ES 10012836 T ES10012836 T ES 10012836T ES 2477284 T3 ES2477284 T3 ES 2477284T3
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| US246524 | 1994-05-20 | ||
| US11/246,524 US7595167B2 (en) | 2005-10-11 | 2005-10-11 | Alzheimer's disease-specific alterations of the Erk1/Erk2 phosphorylation ratio |
| WOPCT/US2005/036014 | 2005-10-11 | ||
| PCT/US2005/036014 WO2007043998A1 (en) | 2005-10-11 | 2005-10-11 | Alzheimer’s disease-specific alterations of the erk1/erk2 phosphorylation ratio |
| WOPCT/US2006/022156 | 2006-06-07 | ||
| PCT/US2006/022156 WO2007044094A1 (en) | 2005-10-11 | 2006-06-07 | Alzheimer's disease-specific alterations of the erk1/erk2 phosphorylation ratio as alzheimer's disease-specific molecular biomarkers (adsmb) |
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| ES2477284T3 true ES2477284T3 (es) | 2014-07-16 |
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| Application Number | Title | Priority Date | Filing Date |
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| ES10011289.5T Active ES2596881T3 (es) | 2005-10-11 | 2006-09-25 | Kit para el diagnóstico de la Enfermedad de Alzheimer |
| ES10012836.2T Active ES2477284T3 (es) | 2005-10-11 | 2006-09-25 | Método de monitorización de la progresión de la enfermedad de Alzheimer por medición de un biomarcador |
| ES06825096T Active ES2323813T3 (es) | 2005-10-11 | 2006-09-25 | Alteraciones especificas de la enfermedad de alzheimer de la proporcion de fosforilacion erk1/erk2 - biomarcadores moleculares especificos de la enfermedad de alzheimer (adsmb). |
| ES10011288.7T Active ES2588376T3 (es) | 2005-10-11 | 2006-09-25 | Procedimientos para la identificación de tratamientos de la enfermedad de Alzheimer |
| ES08020258T Active ES2412268T3 (es) | 2005-10-11 | 2006-09-25 | Alteraciones específicas de la Enfermedad de Alzheimer de la relación de fosforilación ERK1/ERK2 como biomarcadores moleculares específicos de la Enfermedad de Alzheimer (ADSMB) |
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| ES10011289.5T Active ES2596881T3 (es) | 2005-10-11 | 2006-09-25 | Kit para el diagnóstico de la Enfermedad de Alzheimer |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES06825096T Active ES2323813T3 (es) | 2005-10-11 | 2006-09-25 | Alteraciones especificas de la enfermedad de alzheimer de la proporcion de fosforilacion erk1/erk2 - biomarcadores moleculares especificos de la enfermedad de alzheimer (adsmb). |
| ES10011288.7T Active ES2588376T3 (es) | 2005-10-11 | 2006-09-25 | Procedimientos para la identificación de tratamientos de la enfermedad de Alzheimer |
| ES08020258T Active ES2412268T3 (es) | 2005-10-11 | 2006-09-25 | Alteraciones específicas de la Enfermedad de Alzheimer de la relación de fosforilación ERK1/ERK2 como biomarcadores moleculares específicos de la Enfermedad de Alzheimer (ADSMB) |
Country Status (10)
| Country | Link |
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| US (1) | US20180024146A1 (enExample) |
| EP (5) | EP2322936A1 (enExample) |
| JP (1) | JP4908514B2 (enExample) |
| KR (2) | KR20140002073A (enExample) |
| AT (1) | ATE431558T1 (enExample) |
| CA (1) | CA2625300C (enExample) |
| DE (1) | DE602006006855D1 (enExample) |
| ES (5) | ES2596881T3 (enExample) |
| TW (2) | TW201413246A (enExample) |
| WO (1) | WO2007044094A1 (enExample) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1385531B1 (en) | 2001-02-27 | 2008-05-07 | Blanchette Rockefeller Neurosciences Institute | Alzheimer's disease diagnosis based on mitogen-activated protein kinase phosphorylation |
| US6825229B2 (en) | 2002-03-07 | 2004-11-30 | Blanchette Rockefeller Neurosciences Institute | Methods for Alzheimer's Disease treatment and cognitive enhancement |
| US20050065205A1 (en) | 2002-03-07 | 2005-03-24 | Daniel Alkon | Methods for Alzheimer's disease treatment and cognitive enhance |
| TW201207390A (en) | 2004-05-18 | 2012-02-16 | Brni Neurosciences Inst | Method for screening agent for antidepressant activity |
| US7595167B2 (en) | 2005-10-11 | 2009-09-29 | Blanchette Rockefeller Neurosciences Institute | Alzheimer's disease-specific alterations of the Erk1/Erk2 phosphorylation ratio |
| US20090029873A1 (en) | 2005-10-11 | 2009-01-29 | Blanchette Rockefeller Neurosciences Institute | Alzheimer's Disease-Specific Alterations of the Erk1/Erk2 Phosphorylation Ratio-Alzheimer's Disease-Specific Molecular Biomarkers (Adsmb) |
| JP2009544753A (ja) * | 2006-07-28 | 2009-12-17 | ブランシェット・ロックフェラー・ニューロサイエンスィズ・インスティテュート | 細胞成長、シナプスリモデリング及び長期記憶の固定を刺激する方法 |
| EP2121000B1 (en) | 2007-02-09 | 2015-09-23 | Blanchette Rockefeller Neurosciences, Institute | Therapeutic effects of bryostatins, bryologs, and other related substances on head trauma-induced memory impairment and brain injury |
| WO2010014588A1 (en) | 2008-07-28 | 2010-02-04 | Blanchette Rockefeller Neurosciences Institute | Stimulus-elicited genomic profile markers of alzheimer's disease |
| US8163800B2 (en) | 2008-07-28 | 2012-04-24 | Blanchette Rockefeller Neurosciences Institute | PKC-activating compounds for the treatment of neurodegenerative diseases |
| KR20110057188A (ko) * | 2008-08-27 | 2011-05-31 | 하. 룬트벡 아크티에 셀스카브 | 바이오마커 프로파일 측정 시스템 및 방법 |
| JP6013184B2 (ja) * | 2009-10-02 | 2016-10-25 | ブランシェット・ロックフェラー・ニューロサイエンスィズ・インスティテュート | アルツハイマー病末梢細胞におけるｐｋｃアイソザイムプロセッシングの異常変化 |
| CA2776501C (en) | 2009-10-02 | 2022-04-19 | Blanchette Rockefeller Neurosciences Institute | Fibroblast growth patterns for diagnosis of alzheimer's disease |
| EP2707693B1 (en) * | 2011-05-12 | 2016-10-12 | Florin V. Chirila | Peripheral diagnostic methods for screening alzheimer's disease using beta amyloid and intercellular communication |
| WO2013071281A1 (en) | 2011-11-13 | 2013-05-16 | Blanchette Rockefeller Neurosciences Institute | Esters of dcpla and methods of treatment using the same |
| KR101351978B1 (ko) * | 2012-10-30 | 2014-01-16 | 주식회사 코씨드바이오팜 | 참치 안구 파쇄물을 유효성분으로 포함하는 관절염 예방 또는 치료용 약제학적 조성물 및 식품 조성물 |
| EP3090261B8 (en) * | 2014-01-03 | 2019-06-26 | The West Virginia University Board of Governors on behalf of West Virginia University | Convergence of aggregation rate with validated peripheral diagnostics for alzheimer's disease |
| WO2018183703A1 (en) | 2017-03-31 | 2018-10-04 | NeuroDiagnostics LLC | Lymphocyte-based morphometric test for alzheimer's disease |
| US20220211700A1 (en) * | 2019-05-23 | 2022-07-07 | Indiana University Research And Technology Corporation | Methods for Objective Assessment of Memory, Early Detection of Risk for Alzheimer's Disease, Matching Individuals With Treatments, Monitoring Response to Treatment, and New Methods of Use for Drugs |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
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| JP4374316B2 (ja) * | 1993-01-25 | 2009-12-02 | 武田薬品工業株式会社 | β−アミロイドまたはその誘導体に対する抗体およびその用途 |
| US6107050A (en) | 1993-05-03 | 2000-08-22 | The United States Of America As Represented By The Department Of Health And Human Services | Diagnostic test for alzheimers disease |
| US20030108956A1 (en) * | 1993-05-03 | 2003-06-12 | Alkon Daniel L. | Cell tests for Alzheimer's disease |
| US7427392B1 (en) * | 1994-11-14 | 2008-09-23 | Elan Pharmaceuticals, Inc. | Methods for aiding in the diagnosis of alzheimer's disease by measuring amyloid-β peptide (x-≧41) and tau |
| US20030165481A1 (en) * | 2000-02-24 | 2003-09-04 | Hersh Louis B. | Amyloid peptide inactivating enzyme to treat Alzheimer's disease |
| EP1385531B1 (en) | 2001-02-27 | 2008-05-07 | Blanchette Rockefeller Neurosciences Institute | Alzheimer's disease diagnosis based on mitogen-activated protein kinase phosphorylation |
| US6825229B2 (en) * | 2002-03-07 | 2004-11-30 | Blanchette Rockefeller Neurosciences Institute | Methods for Alzheimer's Disease treatment and cognitive enhancement |
| KR100574017B1 (ko) | 2003-08-11 | 2006-04-26 | 삼성전자주식회사 | 잉크젯 프린터의 잉크 카트리지 |
| US7199386B2 (en) | 2004-07-29 | 2007-04-03 | General Electric Company | System and method for detecting defects in a light-management film |
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2006
- 2006-06-07 WO PCT/US2006/022156 patent/WO2007044094A1/en not_active Ceased
- 2006-09-25 EP EP10011290A patent/EP2322936A1/en not_active Withdrawn
- 2006-09-25 JP JP2008535546A patent/JP4908514B2/ja not_active Expired - Fee Related
- 2006-09-25 EP EP10011288.7A patent/EP2339349B1/en active Active
- 2006-09-25 ES ES10011289.5T patent/ES2596881T3/es active Active
- 2006-09-25 CA CA2625300A patent/CA2625300C/en active Active
- 2006-09-25 EP EP10012836.2A patent/EP2317321B1/en active Active
- 2006-09-25 ES ES10012836.2T patent/ES2477284T3/es active Active
- 2006-09-25 EP EP10011289.5A patent/EP2322934B1/en active Active
- 2006-09-25 DE DE602006006855T patent/DE602006006855D1/de active Active
- 2006-09-25 ES ES06825096T patent/ES2323813T3/es active Active
- 2006-09-25 ES ES10011288.7T patent/ES2588376T3/es active Active
- 2006-09-25 ES ES08020258T patent/ES2412268T3/es active Active
- 2006-09-25 AT AT06825096T patent/ATE431558T1/de not_active IP Right Cessation
- 2006-09-25 KR KR1020137031223A patent/KR20140002073A/ko not_active Withdrawn
- 2006-09-25 EP EP08020258A patent/EP2031398B1/en active Active
- 2006-10-11 TW TW102146766A patent/TW201413246A/zh unknown
- 2006-10-11 TW TW095137389A patent/TWI448688B/zh not_active IP Right Cessation
-
2008
- 2008-05-08 KR KR1020087011105A patent/KR101375552B1/ko not_active Expired - Fee Related
-
2017
- 2017-09-29 US US15/719,714 patent/US20180024146A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| ATE431558T1 (de) | 2009-05-15 |
| ES2596881T3 (es) | 2017-01-12 |
| CA2625300C (en) | 2018-01-02 |
| US20180024146A1 (en) | 2018-01-25 |
| TW201413246A (zh) | 2014-04-01 |
| EP2031398B1 (en) | 2013-02-13 |
| EP2322936A1 (en) | 2011-05-18 |
| KR101375552B1 (ko) | 2014-03-24 |
| KR20140002073A (ko) | 2014-01-07 |
| JP2009511905A (ja) | 2009-03-19 |
| ES2412268T3 (es) | 2013-07-10 |
| CA2625300A1 (en) | 2007-04-26 |
| EP2317321B1 (en) | 2014-04-02 |
| ES2588376T3 (es) | 2016-11-02 |
| EP2322934A1 (en) | 2011-05-18 |
| ES2323813T3 (es) | 2009-07-24 |
| JP4908514B2 (ja) | 2012-04-04 |
| EP2339349B1 (en) | 2016-08-17 |
| TWI448688B (zh) | 2014-08-11 |
| KR20080066785A (ko) | 2008-07-16 |
| EP2317321A1 (en) | 2011-05-04 |
| EP2031398A1 (en) | 2009-03-04 |
| TW200801515A (en) | 2008-01-01 |
| EP2339349A1 (en) | 2011-06-29 |
| EP2322934B1 (en) | 2016-08-31 |
| DE602006006855D1 (de) | 2009-06-25 |
| WO2007044094A1 (en) | 2007-04-19 |
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