ES2416361T3 - Vectores para la expresión de múltiples genes - Google Patents
Vectores para la expresión de múltiples genes Download PDFInfo
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- ES2416361T3 ES2416361T3 ES08708348T ES08708348T ES2416361T3 ES 2416361 T3 ES2416361 T3 ES 2416361T3 ES 08708348 T ES08708348 T ES 08708348T ES 08708348 T ES08708348 T ES 08708348T ES 2416361 T3 ES2416361 T3 ES 2416361T3
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
- C12N15/863—Poxviral vectors, e.g. entomopoxvirus
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- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
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- A61K39/00—Medicinal preparations containing antigens or antibodies
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- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/24011—Poxviridae
- C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
- C12N2710/24141—Use of virus, viral particle or viral elements as a vector
- C12N2710/24143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- C12N2840/00—Vectors comprising a special translation-regulating system
- C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron
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- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
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- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Wood Science & Technology (AREA)
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- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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Applications Claiming Priority (3)
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| EP07360019 | 2007-05-15 | ||
| EP07360019 | 2007-05-15 | ||
| PCT/EP2008/051031 WO2008138648A1 (en) | 2007-05-15 | 2008-01-29 | Vectors for multiple gene expression |
Publications (1)
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| ES2416361T3 true ES2416361T3 (es) | 2013-07-31 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES08708348T Active ES2416361T3 (es) | 2007-05-15 | 2008-01-29 | Vectores para la expresión de múltiples genes |
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| Country | Link |
|---|---|
| US (1) | US8337859B2 (enExample) |
| EP (1) | EP2162544B1 (enExample) |
| JP (1) | JP5474767B2 (enExample) |
| KR (1) | KR101514473B1 (enExample) |
| CN (1) | CN101688223B (enExample) |
| AR (1) | AR065075A1 (enExample) |
| AU (1) | AU2008250520B2 (enExample) |
| BR (1) | BRPI0810305A2 (enExample) |
| CA (1) | CA2686772C (enExample) |
| ES (1) | ES2416361T3 (enExample) |
| IL (1) | IL201963A (enExample) |
| MX (1) | MX2009012272A (enExample) |
| PE (1) | PE20090483A1 (enExample) |
| RU (1) | RU2462513C2 (enExample) |
| TW (1) | TW200844231A (enExample) |
| WO (1) | WO2008138648A1 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CA2687304A1 (en) | 2007-05-15 | 2008-11-20 | Transgene S.A. | Signaling peptides |
| EP2389443B1 (en) | 2009-01-23 | 2018-11-14 | Roger Williams Hospital | Retroviral vectors encoding multiple highly homologous non-viral polypeptides and the use of same |
| CA2770075C (en) * | 2009-08-07 | 2021-08-24 | Perrine Martin | Composition for treating hbv infection |
| US8795684B2 (en) | 2010-04-16 | 2014-08-05 | Charite-Universitaetsmedizin Berlin | Agent for use in the topical or local treatment of cervical dysplasias |
| GB201016471D0 (en) * | 2010-09-30 | 2010-11-17 | Isis Innovation | Viral vector immunogenic compositions |
| US9216213B2 (en) * | 2011-04-20 | 2015-12-22 | Merial, Inc. | Adjuvanted rabies vaccine with improved viscosity profile |
| CN104159607A (zh) * | 2012-01-24 | 2014-11-19 | 桑福德研究院/南达科他大学 | 用于治疗致癌病毒多肽阳性肿瘤的多核苷酸 |
| RU2019107976A (ru) | 2013-02-21 | 2019-08-23 | Тёрнстоун Лимитед Партнершип | Композиция вакцины |
| SG11201702857PA (en) * | 2014-10-14 | 2017-05-30 | Univ Pennsylvania | Recombinant listeria vaccine strains and methods of using the same in cancer immunotherapy |
| JP2019505512A (ja) | 2016-01-08 | 2019-02-28 | バッシボディ アクスイェ セルスカプ | 治療用抗癌ネオエピトープワクチン |
| EP3452087A1 (en) * | 2016-05-02 | 2019-03-13 | Janssen Vaccines & Prevention B.V. | Therapeutic hpv vaccine combinations |
| WO2018060288A1 (en) * | 2016-09-29 | 2018-04-05 | Glaxosmithkline Biologicals S.A. | Compositions and methods of treatment of persistent hpv infection |
| EP3461497A1 (en) * | 2017-09-27 | 2019-04-03 | GlaxoSmithKline Biologicals S.A. | Viral antigens |
| IL283165B2 (en) * | 2018-11-21 | 2024-12-01 | Mayo Found Medical Education & Res | Adenoviruses and methods for using adenoviruses |
| WO2021205027A1 (en) | 2020-04-09 | 2021-10-14 | Vaccibody As | Individualized therapeutic anticancer vaccine |
| NL2025475B1 (en) * | 2020-04-30 | 2021-11-09 | Ribopro B V | Rna molecules with decreased immunogenicity and methods for reducing rna immunogenicity |
| KR20240086779A (ko) * | 2022-12-05 | 2024-06-19 | 경상국립대학교산학협력단 | 다중 단백질의 발현을 위한 신규 핵산 구조체 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9105383D0 (en) * | 1991-03-14 | 1991-05-01 | Immunology Ltd | An immunotherapeutic for cervical cancer |
| DE69828284T2 (de) | 1997-06-30 | 2005-12-08 | Nippon Kayaku K.K. | Naphthyridinderivate oder salze davon |
| FR2766091A1 (fr) * | 1997-07-18 | 1999-01-22 | Transgene Sa | Composition antitumorale a base de polypeptide immunogene de localisation cellulaire modifiee |
| FR2774699B1 (fr) * | 1997-11-17 | 2003-10-03 | Rhone Poulenc Rorer Sa | Methode de reduction des evenements de recombinaison homologue |
| US7001995B1 (en) * | 1999-08-25 | 2006-02-21 | Merck & Co., Inc. | Synthetic human papillomavirus genes |
| ES2233437T3 (es) * | 1999-08-25 | 2005-06-16 | MERCK & CO., INC. | Genes sinteticos del papilomavirus optimizados para expresion en celulas humanas. |
| EP1427443A4 (en) * | 2001-08-23 | 2006-03-08 | Merck & Co Inc | VACCINES WITH PAPILLOMA VIRUS E PROTEINS DELIVERED BY A VIRAL VECTOR |
| UA82479C2 (uk) * | 2002-05-16 | 2008-04-25 | Бавариан Нордика А/С | Міжгенні регіони як сайти вставки в геном модифікованого вірусу коров'ячої віспи ankara (mva) |
| CL2008000249A1 (es) * | 2007-01-30 | 2008-05-30 | Transgene Sa | Uso de una molecula de acido nucleico que codifica al menos un polipeptido e2 del papilomavirus, un vector o una particula virica infecciosa que la comprenda para tratar una infeccion permanente por papilomavirus causada por al menos un papilomavirus |
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2008
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- 2008-01-29 EP EP08708348.1A patent/EP2162544B1/en not_active Not-in-force
- 2008-01-29 MX MX2009012272A patent/MX2009012272A/es active IP Right Grant
- 2008-01-29 PE PE2008000210A patent/PE20090483A1/es not_active Application Discontinuation
- 2008-01-29 AR ARP080100356A patent/AR065075A1/es not_active Application Discontinuation
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- 2008-01-29 RU RU2009144898/10A patent/RU2462513C2/ru active
- 2008-01-29 CN CN200880016061XA patent/CN101688223B/zh not_active Expired - Fee Related
- 2008-01-29 BR BRPI0810305A patent/BRPI0810305A2/pt not_active Application Discontinuation
- 2008-01-29 TW TW097103228A patent/TW200844231A/zh unknown
- 2008-01-29 AU AU2008250520A patent/AU2008250520B2/en not_active Ceased
- 2008-01-29 US US12/599,971 patent/US8337859B2/en not_active Expired - Fee Related
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2009
- 2009-11-05 IL IL201963A patent/IL201963A/en active IP Right Grant
Also Published As
| Publication number | Publication date |
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| AU2008250520A1 (en) | 2008-11-20 |
| WO2008138648A1 (en) | 2008-11-20 |
| HK1135731A1 (en) | 2010-06-11 |
| TW200844231A (en) | 2008-11-16 |
| CN101688223B (zh) | 2013-07-31 |
| IL201963A0 (en) | 2011-08-01 |
| IL201963A (en) | 2013-09-30 |
| EP2162544A1 (en) | 2010-03-17 |
| JP5474767B2 (ja) | 2014-04-16 |
| US20100303838A1 (en) | 2010-12-02 |
| EP2162544B1 (en) | 2013-04-17 |
| AU2008250520B2 (en) | 2013-10-31 |
| RU2462513C2 (ru) | 2012-09-27 |
| PE20090483A1 (es) | 2009-05-20 |
| KR101514473B1 (ko) | 2015-04-22 |
| JP2010526547A (ja) | 2010-08-05 |
| CA2686772A1 (en) | 2008-11-20 |
| KR20100019432A (ko) | 2010-02-18 |
| CN101688223A (zh) | 2010-03-31 |
| CA2686772C (en) | 2015-03-24 |
| US8337859B2 (en) | 2012-12-25 |
| RU2009144898A (ru) | 2011-06-20 |
| MX2009012272A (es) | 2009-12-01 |
| AR065075A1 (es) | 2009-05-13 |
| BRPI0810305A2 (pt) | 2018-07-10 |
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