CN101688223B - 用于多基因表达的载体 - Google Patents

用于多基因表达的载体 Download PDF

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Publication number
CN101688223B
CN101688223B CN200880016061XA CN200880016061A CN101688223B CN 101688223 B CN101688223 B CN 101688223B CN 200880016061X A CN200880016061X A CN 200880016061XA CN 200880016061 A CN200880016061 A CN 200880016061A CN 101688223 B CN101688223 B CN 101688223B
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hpv
nucleic acid
acid molecule
polypeptide
carrier
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Chinese (zh)
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CN101688223A (zh
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N·西尔韦斯特雷
D·施密特
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Transgene SA
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Transgene SA
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    • C12N15/09—Recombinant DNA-technology
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
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    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
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    • C12N2710/00011—Details
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    • C12N2710/00011—Details
    • C12N2710/20011—Papillomaviridae
    • C12N2710/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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    • C12N2710/00011—Details
    • C12N2710/24011—Poxviridae
    • C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
    • C12N2710/24141—Use of virus, viral particle or viral elements as a vector
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    • C12N2840/00—Vectors comprising a special translation-regulating system
    • C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron

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  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
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  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
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  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mycology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN200880016061XA 2007-05-15 2008-01-29 用于多基因表达的载体 Expired - Fee Related CN101688223B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07360019 2007-05-15
EP07360019.9 2007-05-15
PCT/EP2008/051031 WO2008138648A1 (en) 2007-05-15 2008-01-29 Vectors for multiple gene expression

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CN101688223A CN101688223A (zh) 2010-03-31
CN101688223B true CN101688223B (zh) 2013-07-31

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US (1) US8337859B2 (enExample)
EP (1) EP2162544B1 (enExample)
JP (1) JP5474767B2 (enExample)
KR (1) KR101514473B1 (enExample)
CN (1) CN101688223B (enExample)
AR (1) AR065075A1 (enExample)
AU (1) AU2008250520B2 (enExample)
BR (1) BRPI0810305A2 (enExample)
CA (1) CA2686772C (enExample)
ES (1) ES2416361T3 (enExample)
IL (1) IL201963A (enExample)
MX (1) MX2009012272A (enExample)
PE (1) PE20090483A1 (enExample)
RU (1) RU2462513C2 (enExample)
TW (1) TW200844231A (enExample)
WO (1) WO2008138648A1 (enExample)

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CA2687304A1 (en) 2007-05-15 2008-11-20 Transgene S.A. Signaling peptides
EP2389443B1 (en) 2009-01-23 2018-11-14 Roger Williams Hospital Retroviral vectors encoding multiple highly homologous non-viral polypeptides and the use of same
CA2770075C (en) * 2009-08-07 2021-08-24 Perrine Martin Composition for treating hbv infection
US8795684B2 (en) 2010-04-16 2014-08-05 Charite-Universitaetsmedizin Berlin Agent for use in the topical or local treatment of cervical dysplasias
GB201016471D0 (en) * 2010-09-30 2010-11-17 Isis Innovation Viral vector immunogenic compositions
US9216213B2 (en) * 2011-04-20 2015-12-22 Merial, Inc. Adjuvanted rabies vaccine with improved viscosity profile
CN104159607A (zh) * 2012-01-24 2014-11-19 桑福德研究院/南达科他大学 用于治疗致癌病毒多肽阳性肿瘤的多核苷酸
RU2019107976A (ru) 2013-02-21 2019-08-23 Тёрнстоун Лимитед Партнершип Композиция вакцины
SG11201702857PA (en) * 2014-10-14 2017-05-30 Univ Pennsylvania Recombinant listeria vaccine strains and methods of using the same in cancer immunotherapy
JP2019505512A (ja) 2016-01-08 2019-02-28 バッシボディ アクスイェ セルスカプ 治療用抗癌ネオエピトープワクチン
EP3452087A1 (en) * 2016-05-02 2019-03-13 Janssen Vaccines & Prevention B.V. Therapeutic hpv vaccine combinations
WO2018060288A1 (en) * 2016-09-29 2018-04-05 Glaxosmithkline Biologicals S.A. Compositions and methods of treatment of persistent hpv infection
EP3461497A1 (en) * 2017-09-27 2019-04-03 GlaxoSmithKline Biologicals S.A. Viral antigens
IL283165B2 (en) * 2018-11-21 2024-12-01 Mayo Found Medical Education & Res Adenoviruses and methods for using adenoviruses
WO2021205027A1 (en) 2020-04-09 2021-10-14 Vaccibody As Individualized therapeutic anticancer vaccine
NL2025475B1 (en) * 2020-04-30 2021-11-09 Ribopro B V Rna molecules with decreased immunogenicity and methods for reducing rna immunogenicity
KR20240086779A (ko) * 2022-12-05 2024-06-19 경상국립대학교산학협력단 다중 단백질의 발현을 위한 신규 핵산 구조체

Citations (1)

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US6410298B1 (en) * 1997-11-17 2002-06-25 Aventis Pharma S.A. Adenovirus vectors and method for reducing homologous recombination phenomena

Family Cites Families (8)

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GB9105383D0 (en) * 1991-03-14 1991-05-01 Immunology Ltd An immunotherapeutic for cervical cancer
DE69828284T2 (de) 1997-06-30 2005-12-08 Nippon Kayaku K.K. Naphthyridinderivate oder salze davon
FR2766091A1 (fr) * 1997-07-18 1999-01-22 Transgene Sa Composition antitumorale a base de polypeptide immunogene de localisation cellulaire modifiee
US7001995B1 (en) * 1999-08-25 2006-02-21 Merck & Co., Inc. Synthetic human papillomavirus genes
ES2233437T3 (es) * 1999-08-25 2005-06-16 MERCK & CO., INC. Genes sinteticos del papilomavirus optimizados para expresion en celulas humanas.
EP1427443A4 (en) * 2001-08-23 2006-03-08 Merck & Co Inc VACCINES WITH PAPILLOMA VIRUS E PROTEINS DELIVERED BY A VIRAL VECTOR
UA82479C2 (uk) * 2002-05-16 2008-04-25 Бавариан Нордика А/С Міжгенні регіони як сайти вставки в геном модифікованого вірусу коров'ячої віспи ankara (mva)
CL2008000249A1 (es) * 2007-01-30 2008-05-30 Transgene Sa Uso de una molecula de acido nucleico que codifica al menos un polipeptido e2 del papilomavirus, un vector o una particula virica infecciosa que la comprenda para tratar una infeccion permanente por papilomavirus causada por al menos un papilomavirus

Patent Citations (1)

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Publication number Priority date Publication date Assignee Title
US6410298B1 (en) * 1997-11-17 2002-06-25 Aventis Pharma S.A. Adenovirus vectors and method for reducing homologous recombination phenomena

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AU2008250520A1 (en) 2008-11-20
WO2008138648A1 (en) 2008-11-20
HK1135731A1 (en) 2010-06-11
TW200844231A (en) 2008-11-16
ES2416361T3 (es) 2013-07-31
IL201963A0 (en) 2011-08-01
IL201963A (en) 2013-09-30
EP2162544A1 (en) 2010-03-17
JP5474767B2 (ja) 2014-04-16
US20100303838A1 (en) 2010-12-02
EP2162544B1 (en) 2013-04-17
AU2008250520B2 (en) 2013-10-31
RU2462513C2 (ru) 2012-09-27
PE20090483A1 (es) 2009-05-20
KR101514473B1 (ko) 2015-04-22
JP2010526547A (ja) 2010-08-05
CA2686772A1 (en) 2008-11-20
KR20100019432A (ko) 2010-02-18
CN101688223A (zh) 2010-03-31
CA2686772C (en) 2015-03-24
US8337859B2 (en) 2012-12-25
RU2009144898A (ru) 2011-06-20
MX2009012272A (es) 2009-12-01
AR065075A1 (es) 2009-05-13
BRPI0810305A2 (pt) 2018-07-10

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