ES2379351T3 - Composición que comprende partículas de iscom y microorganismos vivos - Google Patents

Composición que comprende partículas de iscom y microorganismos vivos Download PDF

Info

Publication number
ES2379351T3
ES2379351T3 ES04723123T ES04723123T ES2379351T3 ES 2379351 T3 ES2379351 T3 ES 2379351T3 ES 04723123 T ES04723123 T ES 04723123T ES 04723123 T ES04723123 T ES 04723123T ES 2379351 T3 ES2379351 T3 ES 2379351T3
Authority
ES
Spain
Prior art keywords
iscom
vaccine
virus
ferret
live
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES04723123T
Other languages
English (en)
Spanish (es)
Inventor
Bror Morein
Karin Lövgren Bengtsson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Isconova AB
Original Assignee
Isconova AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=20290755&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2379351(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Isconova AB filed Critical Isconova AB
Application granted granted Critical
Publication of ES2379351T3 publication Critical patent/ES2379351T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/145Orthomyxoviridae, e.g. influenza virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/155Paramyxoviridae, e.g. parainfluenza virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5252Virus inactivated (killed)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55577Saponins; Quil A; QS21; ISCOMS
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/70Multivalent vaccine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/16011Orthomyxoviridae
    • C12N2760/16111Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/18011Paramyxoviridae
    • C12N2760/18611Respirovirus, e.g. Bovine, human parainfluenza 1,3
    • C12N2760/18634Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
ES04723123T 2003-03-24 2004-03-24 Composición que comprende partículas de iscom y microorganismos vivos Expired - Lifetime ES2379351T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE0300795 2003-03-24
SE0300795A SE0300795D0 (sv) 2003-03-24 2003-03-24 Composition comprising iscom particles and live micro-organisms
PCT/SE2004/000451 WO2004084941A1 (en) 2003-03-24 2004-03-24 Composition comprising iscom particles and live micro-organisms

Publications (1)

Publication Number Publication Date
ES2379351T3 true ES2379351T3 (es) 2012-04-25

Family

ID=20290755

Family Applications (1)

Application Number Title Priority Date Filing Date
ES04723123T Expired - Lifetime ES2379351T3 (es) 2003-03-24 2004-03-24 Composición que comprende partículas de iscom y microorganismos vivos

Country Status (11)

Country Link
US (5) US7838019B2 (de)
EP (1) EP1635867B1 (de)
AT (1) ATE544471T1 (de)
AU (1) AU2004224487B2 (de)
BR (1) BRPI0408587A (de)
CA (1) CA2519806C (de)
ES (1) ES2379351T3 (de)
NZ (1) NZ542328A (de)
SE (1) SE0300795D0 (de)
WO (1) WO2004084941A1 (de)
ZA (1) ZA200506988B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0300795D0 (sv) 2003-03-24 2003-03-24 Isconova Ab Composition comprising iscom particles and live micro-organisms
DK1838341T3 (da) 2005-01-20 2013-11-04 Isconova Ab Vaccinesammensætning omfattende et fibronectin bindende protein eller et fibronectinbindende peptid
US7682619B2 (en) 2006-04-06 2010-03-23 Cornell Research Foundation, Inc. Canine influenza virus
WO2011005183A1 (en) * 2009-07-10 2011-01-13 Isconova Ab New composition
GB201016471D0 (en) * 2010-09-30 2010-11-17 Isis Innovation Viral vector immunogenic compositions
CN105555306B (zh) 2013-09-19 2019-12-03 诺瓦瓦克斯股份有限公司 免疫原性中东呼吸综合征冠状病毒(MERS-CoV)组合物和方法
EP3954700A1 (de) 2015-07-16 2022-02-16 Nuritas Limited Anti-inflammatorische peptide aus reisproteinen (oryza sativa) und ihre verwendung
EP3117831A1 (de) 2015-07-16 2017-01-18 Nuritas Limited Peptide zur verwendung bei der förderung des glucosetransports in skelettmuskeln
EP3117830A1 (de) 2015-07-16 2017-01-18 Nuritas Limited Antibakterielle peptide und verwendungen davon
EP3118216A1 (de) 2015-07-16 2017-01-18 Nuritas Limited Zellwachstum und proliferation fördernde peptide und verwendungen davon
EP3118215A1 (de) 2015-07-16 2017-01-18 Nuritas Limited Entzündungshemmende peptide und verwendungen davon
WO2018014936A1 (en) 2016-07-18 2018-01-25 Nuritas Limited Topical compositions
AU2017373651B2 (en) 2016-12-05 2022-03-10 Nuritas Limited Compositions comprising peptide wkdeagkplvk
EP3329905A1 (de) 2016-12-05 2018-06-06 Nuritas Limited Topische kosmetische zusammensetzungen enhaltend ein oligopeptid gegen die hautalterung
WO2019238962A1 (en) 2018-06-14 2019-12-19 University College Cork - National University Of Ireland, Cork Peptide for disease treatment

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2039229T3 (es) * 1986-01-14 1993-09-16 De Staat Der Nederlanden Vertegenwoordigd Door De Minister Van Welzijn, Volksgezondheid En Cultuur Procedimiento para la preparacion de complejos inmunogenicos y composiciones farmaceuticas que contienen estos complejos.
NZ230747A (en) * 1988-09-30 1992-05-26 Bror Morein Immunomodulating matrix comprising a complex of at least one lipid and at least one saponin; certain glycosylated triterpenoid saponins derived from quillaja saponaria molina
GB8919819D0 (en) 1989-09-01 1989-10-18 Coopers Animal Health Complexes having adjuvant activity
NL9002314A (nl) 1990-10-23 1992-05-18 Nederlanden Staat Immunogene complexen, in het bijzonder iscoms.
GB9320668D0 (en) * 1993-10-07 1993-11-24 Secr Defence Liposomes containing particulare materials
JPH10508182A (ja) * 1994-03-09 1998-08-18 パシフィック バイオテク インターナショナル,インコーポレーテッド 活性化ウイルス
AUPM873294A0 (en) * 1994-10-12 1994-11-03 Csl Limited Saponin preparations and use thereof in iscoms
US5676354A (en) * 1995-07-14 1997-10-14 Fuji Photo Film Co., Ltd. Sheet film pack
US5753235A (en) * 1996-02-15 1998-05-19 Heska Corporation Recombinant canine herpesviruses
DE69704011T2 (de) * 1996-10-09 2001-06-07 Akzo Nobel Nv Europäische Vakzinstämme des Fortplanzungs-Atmungs-Syndromsvirus des Sweins (PRRSV)
CA2500911A1 (en) 2002-10-02 2004-04-15 Nordic Vaccine Technology A/S Composition for vaccination
SE0300795D0 (sv) 2003-03-24 2003-03-24 Isconova Ab Composition comprising iscom particles and live micro-organisms

Also Published As

Publication number Publication date
ATE544471T1 (de) 2012-02-15
US20110081378A1 (en) 2011-04-07
US20180369369A1 (en) 2018-12-27
US9901634B2 (en) 2018-02-27
US7838019B2 (en) 2010-11-23
CA2519806C (en) 2012-06-19
US20080095795A1 (en) 2008-04-24
US10813994B2 (en) 2020-10-27
AU2004224487A1 (en) 2004-10-07
CA2519806A1 (en) 2004-10-07
ZA200506988B (en) 2006-07-26
AU2004224487B2 (en) 2009-08-06
WO2004084941A1 (en) 2004-10-07
BRPI0408587A (pt) 2006-03-21
US20200323979A9 (en) 2020-10-15
SE0300795D0 (sv) 2003-03-24
NZ542328A (en) 2009-10-30
EP1635867A1 (de) 2006-03-22
US9205147B2 (en) 2015-12-08
US20160114034A1 (en) 2016-04-28
EP1635867B1 (de) 2012-02-08
US20140120131A1 (en) 2014-05-01

Similar Documents

Publication Publication Date Title
US10813994B2 (en) Composition comprising iscom particles and live micro-organisms
AU2005230708B2 (en) Microfluidized oil-in-water emulsions and vaccine compositions
ES2728949T3 (es) Composiciones adyuvantes novedosas
ES2398235T3 (es) Emulsiones de aceite en agua microfluidizadas y composiciones de vacunas
ES2331952T3 (es) Fraccion de quil a con baja toxicidad y su uso.
JP4636877B2 (ja) 免疫刺激複合体の調製及びその使用
JP6975132B2 (ja) リポソームアジュバント組成物