ES2343246T3 - Formas de dosificacion de compuestos de prostaglandina e estabilizados topicos. - Google Patents
Formas de dosificacion de compuestos de prostaglandina e estabilizados topicos. Download PDFInfo
- Publication number
- ES2343246T3 ES2343246T3 ES03800371T ES03800371T ES2343246T3 ES 2343246 T3 ES2343246 T3 ES 2343246T3 ES 03800371 T ES03800371 T ES 03800371T ES 03800371 T ES03800371 T ES 03800371T ES 2343246 T3 ES2343246 T3 ES 2343246T3
- Authority
- ES
- Spain
- Prior art keywords
- prostaglandin
- dosage form
- compound
- form according
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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- 150000001875 compounds Chemical class 0.000 title claims abstract description 29
- 239000002552 dosage form Substances 0.000 title claims description 19
- -1 PGE compounds Chemical class 0.000 claims abstract description 77
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- 239000003961 penetration enhancing agent Substances 0.000 claims abstract description 17
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- GMVPRGQOIOIIMI-DWKJAMRDSA-N prostaglandin E1 Chemical compound CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(O)=O GMVPRGQOIOIIMI-DWKJAMRDSA-N 0.000 claims description 21
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- 229960000711 alprostadil Drugs 0.000 claims description 19
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- 150000003839 salts Chemical class 0.000 claims description 13
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims description 12
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
- A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Pregnancy & Childbirth (AREA)
- Heart & Thoracic Surgery (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/336,481 US6841574B2 (en) | 2003-01-03 | 2003-01-03 | Topical stabilized prostaglandin E compound dosage forms |
| US336481 | 2003-01-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2343246T3 true ES2343246T3 (es) | 2010-07-27 |
Family
ID=32681022
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES03800371T Expired - Lifetime ES2343246T3 (es) | 2003-01-03 | 2003-12-31 | Formas de dosificacion de compuestos de prostaglandina e estabilizados topicos. |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US6841574B2 (https=) |
| EP (1) | EP1585483B1 (https=) |
| JP (2) | JP2006514068A (https=) |
| KR (2) | KR20050098853A (https=) |
| CN (1) | CN100574763C (https=) |
| AT (1) | ATE468098T1 (https=) |
| AU (1) | AU2003300113B2 (https=) |
| BR (1) | BR0317924A (https=) |
| CA (1) | CA2512015C (https=) |
| DE (1) | DE60332656D1 (https=) |
| DK (1) | DK1585483T3 (https=) |
| ES (1) | ES2343246T3 (https=) |
| IL (1) | IL169425A (https=) |
| PT (1) | PT1585483E (https=) |
| WO (1) | WO2004062632A1 (https=) |
| ZA (1) | ZA200505321B (https=) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050004226A1 (en) * | 1998-12-10 | 2005-01-06 | Nexmed (Holdings), Inc. | Compositions and methods for amelioration of human female sexual dysfunction |
| GB0222522D0 (en) | 2002-09-27 | 2002-11-06 | Controlled Therapeutics Sct | Water-swellable polymers |
| US20050181030A1 (en) * | 2003-01-03 | 2005-08-18 | Mo Y. J. | Topical stabilized prostaglandin E compound dosage forms |
| BRPI0408454A (pt) | 2003-03-21 | 2006-04-04 | Nexmed Holdings Inc | composição tópica, método de tratar a ejaculação precoce, e, uso da composição |
| WO2005051960A2 (en) * | 2003-11-22 | 2005-06-09 | Midwest Research Laboratories, Llc | Hydrocarbyl aminohydrocarbonoates and aminohydrocarbonol hydrocarbonoates as antimicrobial and antiviral agents |
| GB0417401D0 (en) * | 2004-08-05 | 2004-09-08 | Controlled Therapeutics Sct | Stabilised prostaglandin composition |
| CA2610465A1 (en) * | 2005-06-03 | 2006-12-14 | Duramed Pharmaceuticals, Inc. | Pharmaceutical compositions comprising prostanoid-receptor agonists and methods of making and using the same |
| ITMI20051417A1 (it) * | 2005-07-22 | 2007-01-23 | Mipharm S P A | Formulazione topica in forma di gel contenente come ingredienti attivi ciclovit e lidocaina |
| CA2630261A1 (en) * | 2005-12-06 | 2007-06-14 | Monosol Rx, Llc | Topical film compositions for delivery of actives |
| GB0613333D0 (en) | 2006-07-05 | 2006-08-16 | Controlled Therapeutics Sct | Hydrophilic polyurethane compositions |
| GB0613638D0 (en) | 2006-07-08 | 2006-08-16 | Controlled Therapeutics Sct | Polyurethane elastomers |
| US7560489B2 (en) * | 2006-10-11 | 2009-07-14 | Nexmed Holdings, Inc. | Stabilized prostaglandin E composition |
| GB0620685D0 (en) | 2006-10-18 | 2006-11-29 | Controlled Therapeutics Sct | Bioresorbable polymers |
| EP2437684B1 (en) | 2009-06-03 | 2022-06-15 | ForSight Vision5, Inc. | Anterior segment drug delivery |
| WO2012139033A1 (en) | 2011-04-07 | 2012-10-11 | Nexmed Holdings, Inc. | Methods and compositions for treating raynaud's disease |
| EP2755615B1 (en) | 2011-09-14 | 2022-04-06 | Forsight Vision5, Inc. | Ocular insert apparatus |
| DK2911623T3 (da) | 2012-10-26 | 2019-10-28 | Forsight Vision5 Inc | Oftalmisk system til langvarig frigivelse af lægemiddel til øjet |
| US8900625B2 (en) | 2012-12-15 | 2014-12-02 | Nexmed Holdings, Inc. | Antimicrobial compounds and methods of use |
| US20160296532A1 (en) | 2015-04-13 | 2016-10-13 | Forsight Vision5, Inc. | Ocular Insert Composition of a Semi-Crystalline or Crystalline Pharmaceutically Active Agent |
| WO2019142015A1 (es) * | 2018-01-18 | 2019-07-25 | Caicedo Pinto, David Felipe | Composicion farmaceutica para la disfuncion erectil de administracion transdermica via uretral en gotas |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3883576A (en) * | 1971-02-02 | 1975-05-13 | Upjohn Co | Prostaglandin E{HD 3 {B analogs |
| US3826823A (en) * | 1972-09-25 | 1974-07-30 | Syntex Inc | Stabilized prostaglandin preparations |
| US3875300A (en) * | 1972-12-18 | 1975-04-01 | Ortho Pharma Corp | Composition for sustained release of a medicament and method of using same |
| US4136162A (en) * | 1974-07-05 | 1979-01-23 | Schering Aktiengesellschaft | Medicament carriers in the form of film having active substance incorporated therein |
| US5017382A (en) * | 1979-03-21 | 1991-05-21 | National Research Development Corporation | Controlled release compositions (II) |
| JPS5770816A (en) * | 1980-10-17 | 1982-05-01 | Ono Pharmaceut Co Ltd | Multilayered film preparation of prostagladin of prolonged action |
| JPS58134019A (ja) * | 1982-02-05 | 1983-08-10 | Ono Pharmaceut Co Ltd | プロスタグランジン含有持続放出型三層状フイルム製剤及びその製造方法 |
| JPS5948409A (ja) * | 1982-09-10 | 1984-03-19 | Teikoku Seiyaku Kk | 矯正的歯牙移動促進剤 |
| JPS6185315A (ja) * | 1984-10-04 | 1986-04-30 | Teikoku Seiyaku Kk | シ−ト状製剤 |
| IE59361B1 (en) * | 1986-01-24 | 1994-02-09 | Akzo Nv | Pharmaceutical preparation for obtaining a highly viscous hydrogel or suspension |
| US5219885A (en) * | 1987-02-16 | 1993-06-15 | Froelich Juergen | Prostaglandin E1 derivatives as pharmaceutically active agents, and pharmaceutical compositions containing these compounds, especially for transcutaneous administration |
| BR9203277A (pt) * | 1992-08-21 | 1994-03-01 | Cesar Roberto Dias Nahoum | Utilizaccao de drogas eretogenicas e respectivas metodologias de aplicacao |
| US5380760A (en) * | 1993-11-19 | 1995-01-10 | Minnesota Mining And Manufacturing Company | Transdermal prostaglandin composition |
| SE503432C2 (sv) * | 1995-05-05 | 1996-06-10 | Perstorp Ab | Omläggningsset |
| US6593369B2 (en) * | 1997-10-20 | 2003-07-15 | Vivus, Inc. | Methods, compositions, and kits for enhancing female sexual desire and responsiveness |
| US20020004529A1 (en) * | 1997-10-20 | 2002-01-10 | Gary W. Neal | Methods, compositions, and kits for enhancing female sexual desire and responsiveness |
| US6046244A (en) * | 1997-11-05 | 2000-04-04 | Nexmed Holdings, Inc. | Topical compositions for prostaglandin E1 delivery |
| US6414028B1 (en) * | 1997-11-05 | 2002-07-02 | Nexmed Holdings, Inc. | Topical compositions containing prostaglandin E1 |
| US5942545A (en) * | 1998-06-15 | 1999-08-24 | Macrochem Corporation | Composition and method for treating penile erectile dysfunction |
| JP2002518417A (ja) * | 1998-06-25 | 2002-06-25 | ラヴィファム ラボラトリーズ インコーポレーテッド | 勃起機能不全の治療装具及び方法 |
| US6323241B1 (en) * | 2000-01-10 | 2001-11-27 | Nexmed (Holdings) Inc. | Prostaglandin compositions and methods of treatment for male erectile dysfunction |
| KR100402334B1 (ko) * | 2000-06-23 | 2003-10-22 | 환인제약 주식회사 | 알프로스타딜 외용제 |
-
2003
- 2003-01-03 US US10/336,481 patent/US6841574B2/en not_active Expired - Lifetime
- 2003-12-31 BR BR0317924-9A patent/BR0317924A/pt not_active Application Discontinuation
- 2003-12-31 DK DK03800371.1T patent/DK1585483T3/da active
- 2003-12-31 AT AT03800371T patent/ATE468098T1/de active
- 2003-12-31 DE DE60332656T patent/DE60332656D1/de not_active Expired - Lifetime
- 2003-12-31 ES ES03800371T patent/ES2343246T3/es not_active Expired - Lifetime
- 2003-12-31 KR KR1020057012502A patent/KR20050098853A/ko not_active Withdrawn
- 2003-12-31 JP JP2004566647A patent/JP2006514068A/ja active Pending
- 2003-12-31 CN CN200380110112A patent/CN100574763C/zh not_active Expired - Fee Related
- 2003-12-31 PT PT03800371T patent/PT1585483E/pt unknown
- 2003-12-31 KR KR1020117008180A patent/KR101174788B1/ko not_active Expired - Fee Related
- 2003-12-31 CA CA2512015A patent/CA2512015C/en not_active Expired - Lifetime
- 2003-12-31 WO PCT/US2003/041658 patent/WO2004062632A1/en not_active Ceased
- 2003-12-31 AU AU2003300113A patent/AU2003300113B2/en not_active Expired
- 2003-12-31 EP EP03800371A patent/EP1585483B1/en not_active Expired - Lifetime
-
2005
- 2005-06-27 IL IL169425A patent/IL169425A/en unknown
- 2005-06-30 ZA ZA200505321A patent/ZA200505321B/en unknown
-
2011
- 2011-09-14 JP JP2011200752A patent/JP5395138B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ZA200505321B (en) | 2006-04-26 |
| PT1585483E (pt) | 2010-06-17 |
| DE60332656D1 (de) | 2010-07-01 |
| AU2003300113B2 (en) | 2010-03-11 |
| CN100574763C (zh) | 2009-12-30 |
| KR101174788B1 (ko) | 2012-08-20 |
| US20040131664A1 (en) | 2004-07-08 |
| EP1585483A4 (en) | 2006-04-19 |
| JP2006514068A (ja) | 2006-04-27 |
| AU2003300113A1 (en) | 2004-08-10 |
| JP5395138B2 (ja) | 2014-01-22 |
| BR0317924A (pt) | 2005-11-29 |
| CA2512015A1 (en) | 2004-07-29 |
| KR20050098853A (ko) | 2005-10-12 |
| EP1585483B1 (en) | 2010-05-19 |
| DK1585483T3 (da) | 2010-07-19 |
| ATE468098T1 (de) | 2010-06-15 |
| HK1090293A1 (zh) | 2006-12-22 |
| WO2004062632A1 (en) | 2004-07-29 |
| CN1756532A (zh) | 2006-04-05 |
| EP1585483A1 (en) | 2005-10-19 |
| JP2012036196A (ja) | 2012-02-23 |
| US6841574B2 (en) | 2005-01-11 |
| CA2512015C (en) | 2011-11-08 |
| KR20110042138A (ko) | 2011-04-22 |
| IL169425A (en) | 2010-11-30 |
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