ES233470A1 - PROCEDIMIENTO PARA LA PREPARACIoN DE DERIVADOR DE 2-IDROXI-BENZOQUINOLEIZINA - Google Patents

PROCEDIMIENTO PARA LA PREPARACIoN DE DERIVADOR DE 2-IDROXI-BENZOQUINOLEIZINA

Info

Publication number
ES233470A1
ES233470A1 ES0233470A ES233470A ES233470A1 ES 233470 A1 ES233470 A1 ES 233470A1 ES 0233470 A ES0233470 A ES 0233470A ES 233470 A ES233470 A ES 233470A ES 233470 A1 ES233470 A1 ES 233470A1
Authority
ES
Spain
Prior art keywords
hydroxy
benzo
dimethoxy
quinolizine
hexahydro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES0233470A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of ES233470A1 publication Critical patent/ES233470A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/03—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/04—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing a quinolizine ring system condensed with only one six-membered carbocyclic ring, e.g. julolidine
    • C07D455/06—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing a quinolizine ring system condensed with only one six-membered carbocyclic ring, e.g. julolidine containing benzo [a] quinolizine ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Procedimiento para la preparación de derivados de 2-hidroxi-benzoquinoleizinacaracterizado porque se reduce una 2-oxo-benzo[a]quinoleizina de fórmula general **(Ver fórmula)** en la cual R1 y R2 representan hidrógenogrupos hidroxi o alcoxio conjuntamenteun radical alcoilendioxiy R3 representa un grupo alcoílo que puede contener oxígeno bajo forma de función étero un radical alcenilo o aralcoíloy en la cual el anillo isocíclico puede estar parcialmente hidrogenadoyen caso dadose transforma el producto de reducción en una sal.
ES0233470A 1956-02-08 1957-02-07 PROCEDIMIENTO PARA LA PREPARACIoN DE DERIVADOR DE 2-IDROXI-BENZOQUINOLEIZINA Expired ES233470A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH341161T 1956-02-08

Publications (1)

Publication Number Publication Date
ES233470A1 true ES233470A1 (es) 1957-10-16

Family

ID=4505675

Family Applications (1)

Application Number Title Priority Date Filing Date
ES0233470A Expired ES233470A1 (es) 1956-02-08 1957-02-07 PROCEDIMIENTO PARA LA PREPARACIoN DE DERIVADOR DE 2-IDROXI-BENZOQUINOLEIZINA

Country Status (8)

Country Link
AT (1) AT196875B (es)
BE (1) BE554816A (es)
CH (1) CH341161A (es)
DE (1) DE1082912B (es)
DK (1) DK89401C (es)
ES (1) ES233470A1 (es)
FR (1) FR1231641A (es)
GB (1) GB800969A (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU175890B (en) * 1977-06-15 1980-11-28 Chinoin Gyogyszer Es Vegyeszet Process for producing new 1,2,3,4,6,7-hexahydro-11-b-alpha-benzo-square bracket-a-square brecket closed-quinolyzine derivatives
GB2463452A (en) * 2008-09-08 2010-03-17 Cambridge Lab Desmethyl derivatives of tetrabenazine and pharmaceutical compositions thereof
JP2013501810A (ja) 2009-08-12 2013-01-17 ヴァリーント インターナショナル（バルバドス）エスアールエル 医薬組成物
GB201705302D0 (en) 2017-04-01 2017-05-17 Adeptio Pharmaceuticals Ltd Pharmaceutical compositions
GB201705303D0 (en) 2017-04-01 2017-05-17 Adeptio Pharmaceuticals Ltd Pharmaceutical compositions
GB201705306D0 (en) 2017-04-01 2017-05-17 Adeptio Pharmaceuticals Ltd Pharmaceutical compositions
GB201705304D0 (en) 2017-04-01 2017-05-17 Adeptio Pharmaceuticals Ltd Pharmaceutical compositions
JP7250692B2 (ja) * 2017-04-01 2023-04-03 アデプティオ ファーマシューティカルズ リミテッド 運動障害の治療における使用のためのジヒドロテトラベナジン
GB201808464D0 (en) 2018-05-23 2018-07-11 Adeptio Pharmaceuticals Ltd Pharmaceutical compounds for use in treating huntington's disease

Also Published As

Publication number Publication date
FR1231641A (fr) 1960-09-30
CH341161A (de) 1959-09-30
BE554816A (fr) 1960-02-12
DK89401C (da) 1960-07-25
DE1082912B (de) 1960-06-09
AT196875B (de) 1958-03-25
GB800969A (en) 1958-09-03

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