ES2333772T3 - Polipeptidos homologos de il-17 y il-17r y sus utilizaciones terapeuticas. - Google Patents
Polipeptidos homologos de il-17 y il-17r y sus utilizaciones terapeuticas. Download PDFInfo
- Publication number
- ES2333772T3 ES2333772T3 ES00989401T ES00989401T ES2333772T3 ES 2333772 T3 ES2333772 T3 ES 2333772T3 ES 00989401 T ES00989401 T ES 00989401T ES 00989401 T ES00989401 T ES 00989401T ES 2333772 T3 ES2333772 T3 ES 2333772T3
- Authority
- ES
- Spain
- Prior art keywords
- polypeptide
- cell
- pro10272
- amino acid
- pro5801
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P17/06—Antipsoriatics
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- A61P37/02—Immunomodulators
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
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- A—HUMAN NECESSITIES
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- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
- C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Neurosurgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Obesity (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Rheumatology (AREA)
- Biochemistry (AREA)
- Endocrinology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Molecular Biology (AREA)
- Nutrition Science (AREA)
- Cardiology (AREA)
Applications Claiming Priority (28)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17209699P | 1999-12-23 | 1999-12-23 | |
| US172096P | 1999-12-23 | ||
| PCT/US1999/031274 WO2000053752A2 (en) | 1999-03-08 | 1999-12-30 | Promotion or inhibition of angiogenesis and cardiovascularization |
| WOUS99/31274 | 1999-12-30 | ||
| US17548100P | 2000-01-11 | 2000-01-11 | |
| US175481P | 2000-01-11 | ||
| WOUS00/04341 | 2000-02-18 | ||
| PCT/US2000/004341 WO2000053756A2 (en) | 1999-03-08 | 2000-02-18 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| WOUS00/05841 | 2000-03-02 | ||
| US19100700P | 2000-03-21 | 2000-03-21 | |
| WOUS00/07532 | 2000-03-21 | ||
| PCT/US2000/007532 WO2000070050A1 (en) | 1999-05-14 | 2000-03-21 | Compositions and methods for the treatment of immune related diseases |
| US191007P | 2000-03-21 | ||
| PCT/US2000/015264 WO2000073452A2 (en) | 1999-06-02 | 2000-06-02 | Compositions and methods for the treatment of immune related diseases |
| WOUS00/15264 | 2000-06-02 | ||
| US21380700P | 2000-06-22 | 2000-06-22 | |
| US213807P | 2000-06-22 | ||
| US64484800A | 2000-08-22 | 2000-08-22 | |
| US644848 | 2000-08-22 | ||
| PCT/US2000/023328 WO2001016318A2 (en) | 1999-09-01 | 2000-08-24 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| WOUS00/23328 | 2000-08-24 | ||
| US24283700P | 2000-10-24 | 2000-10-24 | |
| US242837P | 2000-10-24 | ||
| WOUS00/30873 | 2000-11-10 | ||
| PCT/US2000/030873 WO2001040465A2 (en) | 1999-11-30 | 2000-11-10 | Compositions and methods for the treatment of immune related diseases |
| US25364600P | 2000-11-28 | 2000-11-28 | |
| US253646P | 2000-11-28 | ||
| WOUS00/32678 | 2000-12-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2333772T3 true ES2333772T3 (es) | 2010-03-01 |
Family
ID=40140243
Family Applications (7)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES09009972.2T Expired - Lifetime ES2506665T3 (es) | 1999-12-23 | 2000-12-20 | Polipéptidos homólogos IL-17 e IL-17R y usos terapéuticos de los mismos |
| ES07016903T Expired - Lifetime ES2380812T3 (es) | 1999-12-23 | 2000-12-20 | Polipéptidos homólogos a IL-17 y usos terapéuticos de los mismos |
| ES00989401T Expired - Lifetime ES2333772T3 (es) | 1999-12-23 | 2000-12-20 | Polipeptidos homologos de il-17 y il-17r y sus utilizaciones terapeuticas. |
| ES10009491.1T Expired - Lifetime ES2458349T3 (es) | 1999-12-23 | 2000-12-20 | Polipéptidos homólogos IL-17 y usos terapéuticos de los mismos |
| ES07016899T Expired - Lifetime ES2379101T3 (es) | 1999-12-23 | 2000-12-20 | Polipéptidos homólogos IL-17 y usos terapéuticos de los mismos |
| ES07016901T Expired - Lifetime ES2380958T3 (es) | 1999-12-23 | 2000-12-20 | Polipéptidos homólogos IL-17 y utilizaciones terapéuticas de los mismos |
| ES07016902T Expired - Lifetime ES2388748T3 (es) | 1999-12-23 | 2000-12-20 | Polipéptidos homólogos a IL-17 y usos terapéuticos de los mismos |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES09009972.2T Expired - Lifetime ES2506665T3 (es) | 1999-12-23 | 2000-12-20 | Polipéptidos homólogos IL-17 e IL-17R y usos terapéuticos de los mismos |
| ES07016903T Expired - Lifetime ES2380812T3 (es) | 1999-12-23 | 2000-12-20 | Polipéptidos homólogos a IL-17 y usos terapéuticos de los mismos |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES10009491.1T Expired - Lifetime ES2458349T3 (es) | 1999-12-23 | 2000-12-20 | Polipéptidos homólogos IL-17 y usos terapéuticos de los mismos |
| ES07016899T Expired - Lifetime ES2379101T3 (es) | 1999-12-23 | 2000-12-20 | Polipéptidos homólogos IL-17 y usos terapéuticos de los mismos |
| ES07016901T Expired - Lifetime ES2380958T3 (es) | 1999-12-23 | 2000-12-20 | Polipéptidos homólogos IL-17 y utilizaciones terapéuticas de los mismos |
| ES07016902T Expired - Lifetime ES2388748T3 (es) | 1999-12-23 | 2000-12-20 | Polipéptidos homólogos a IL-17 y usos terapéuticos de los mismos |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP1240325B1 (OSRAM) |
| JP (10) | JP5070117B2 (OSRAM) |
| AT (5) | ATE519847T1 (OSRAM) |
| AU (1) | AU2590901A (OSRAM) |
| CA (1) | CA2391374A1 (OSRAM) |
| CY (1) | CY1112334T1 (OSRAM) |
| DK (1) | DK1240325T3 (OSRAM) |
| ES (7) | ES2506665T3 (OSRAM) |
| PT (4) | PT1897944E (OSRAM) |
| WO (1) | WO2001046420A2 (OSRAM) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6562578B1 (en) | 1999-01-11 | 2003-05-13 | Schering Corporation | IL-17-like cytokine binding compounds and antibodies |
| JP3577586B2 (ja) | 1998-05-15 | 2004-10-13 | ジェネンテック・インコーポレーテッド | Il−17相同的ポリペプチドとその治療用途 |
| US7771719B1 (en) | 2000-01-11 | 2010-08-10 | Genentech, Inc. | Pharmaceutical compositions, kits, and therapeutic uses of antagonist antibodies to IL-17E |
| EP1259253A2 (en) * | 2000-02-29 | 2002-11-27 | ZymoGenetics, Inc. | Methods for promoting production of myelin by schwann cells |
| US7718397B2 (en) | 2000-03-21 | 2010-05-18 | Genentech, Inc. | Nucleic acids encoding receptor for IL-17 homologous polypeptides and uses thereof |
| SI1274450T1 (sl) * | 2000-04-18 | 2009-04-30 | Schering Corp | Medicinske uporabe agonistov in antagonistov IL-174 |
| US20030092881A1 (en) * | 2000-05-24 | 2003-05-15 | Gorman Daniel M. | Mammalian receptor proteins; related reagents and methods |
| US20030096969A1 (en) | 2000-06-02 | 2003-05-22 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| WO2002008259A2 (en) * | 2000-07-26 | 2002-01-31 | Zymogenetics, Inc. | Human cytokine receptor |
| EP1529843A3 (en) * | 2000-08-11 | 2005-06-08 | Eli Lilly & Company | Novel secreted proteins and their uses |
| AU2001296229A1 (en) * | 2000-10-13 | 2002-04-29 | Eli Lilly And Company | Methods of using a human il-17-related polypeptide to treat disease |
| US20040171109A1 (en) * | 2000-11-10 | 2004-09-02 | Dominik Haudenschild | IL-17 receptor-like protein, uses thereof, and modulation of catabolic activity of il-17 cytokines on bone and cartilage |
| US20070160576A1 (en) | 2001-06-05 | 2007-07-12 | Genentech, Inc. | IL-17A/F heterologous polypeptides and therapeutic uses thereof |
| AU2002351505B2 (en) * | 2001-10-19 | 2008-04-03 | Genentech, Inc. | Compositions and methods for the diagnosis and treatment of inflammatory bowel disorders |
| EP1562587A4 (en) * | 2002-09-11 | 2006-07-19 | Genentech Inc | COMPOSITIONS AND METHODS FOR THE TREATMENT OF DISEASES OF THE IMMUNE SYSTEM |
| EP2314676A1 (en) * | 2002-11-26 | 2011-04-27 | Genentech, Inc. | Compositions and methods for the treatment of immune related diseases |
| WO2005051988A2 (en) * | 2003-03-03 | 2005-06-09 | Genentech, Inc. | Compositions and methods for the treatment of systemic lupus erythematosis |
| EP2784084B2 (en) * | 2003-07-08 | 2023-10-04 | Novartis Pharma AG | Antagonist antibodies to IL-17A/F heterologous polypeptides |
| ATE395083T1 (de) | 2003-11-21 | 2008-05-15 | Ucb Pharma Sa | Verfahren zur behandlung von multipler sklerose durch hemmung der il-17-aktivität |
| US7501247B2 (en) | 2004-05-03 | 2009-03-10 | Schering Corporation | Method of treating skin inflammation |
| US20050287593A1 (en) | 2004-05-03 | 2005-12-29 | Schering Corporation | Use of cytokine expression to predict skin inflammation; methods of treatment |
| CN101001871A (zh) | 2004-06-10 | 2007-07-18 | 津莫吉尼蒂克斯公司 | 可溶性ZcytoR14、抗ZcytoR14抗体和结合伴侣以及在炎症中的使用方法 |
| JP2008513415A (ja) * | 2004-09-21 | 2008-05-01 | アプライド リサーチ システムズ エーアールエス ホールディング ナームロゼ フェンノートシャップ | 神経疾患の治療および予防のためのil−17fの使用 |
| US20070053872A1 (en) * | 2005-08-04 | 2007-03-08 | Moore Emma E | Treatment of wounds using il-17b |
| US20070249533A1 (en) | 2005-09-28 | 2007-10-25 | Levin Steven D | Il-17a and il-17f antagonists and methods of using the same |
| ATE467640T1 (de) | 2006-02-10 | 2010-05-15 | Zymogenetics Inc | Lösliches il-17rcx4 und verfahren zu dessen anwendung bei entzündungen |
| AU2007310777A1 (en) | 2006-10-26 | 2008-05-02 | Novo Nordisk A/S | IL-21 variants |
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| CN102458437B (zh) | 2009-05-05 | 2015-06-10 | 诺维莫尼公司 | 抗il-17f抗体及其使用方法 |
| WO2010142551A2 (en) * | 2009-06-12 | 2010-12-16 | Ablynx N.V. | Single variable domain (vhh) antibodies to cytokines of the il-17 receptor family |
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2000
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