CY1112334T1 - Ομολογα πολυπεπτιδια il-17 και θεραπευτικες χρησεις αυτων - Google Patents
Ομολογα πολυπεπτιδια il-17 και θεραπευτικες χρησεις αυτωνInfo
- Publication number
- CY1112334T1 CY1112334T1 CY20111100948T CY111100948T CY1112334T1 CY 1112334 T1 CY1112334 T1 CY 1112334T1 CY 20111100948 T CY20111100948 T CY 20111100948T CY 111100948 T CY111100948 T CY 111100948T CY 1112334 T1 CY1112334 T1 CY 1112334T1
- Authority
- CY
- Cyprus
- Prior art keywords
- polypeptides
- present
- homologous
- therapeutic uses
- nucleic acid
- Prior art date
Links
- 230000001225 therapeutic effect Effects 0.000 title 1
- 229920001184 polypeptide Polymers 0.000 abstract 7
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 7
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 7
- 150000007523 nucleic acids Chemical class 0.000 abstract 2
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 239000013598 vector Substances 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
- C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pulmonology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Dermatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Neurosurgery (AREA)
- Gastroenterology & Hepatology (AREA)
- Obesity (AREA)
- Biophysics (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Endocrinology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Rheumatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Transplantation (AREA)
- Cardiology (AREA)
Applications Claiming Priority (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17209699P | 1999-12-23 | 1999-12-23 | |
| US17548100P | 2000-01-11 | 2000-01-11 | |
| US19100700P | 2000-03-21 | 2000-03-21 | |
| US21380700P | 2000-06-22 | 2000-06-22 | |
| US64484800A | 2000-08-22 | 2000-08-22 | |
| US24283700P | 2000-10-24 | 2000-10-24 | |
| US25364600P | 2000-11-28 | 2000-11-28 | |
| EP07016900A EP1897944B1 (en) | 1999-12-23 | 2000-12-20 | IL-17 homologous polypeptides and therapeutic uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1112334T1 true CY1112334T1 (el) | 2015-12-09 |
Family
ID=40140243
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20111100948T CY1112334T1 (el) | 1999-12-23 | 2011-10-04 | Ομολογα πολυπεπτιδια il-17 και θεραπευτικες χρησεις αυτων |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP1240325B1 (OSRAM) |
| JP (10) | JP5070117B2 (OSRAM) |
| AT (5) | ATE444361T1 (OSRAM) |
| AU (1) | AU2590901A (OSRAM) |
| CA (1) | CA2391374A1 (OSRAM) |
| CY (1) | CY1112334T1 (OSRAM) |
| DK (1) | DK1240325T3 (OSRAM) |
| ES (7) | ES2333772T3 (OSRAM) |
| PT (4) | PT1240325E (OSRAM) |
| WO (1) | WO2001046420A2 (OSRAM) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6562578B1 (en) | 1999-01-11 | 2003-05-13 | Schering Corporation | IL-17-like cytokine binding compounds and antibodies |
| CA2328496C (en) | 1998-05-15 | 2016-01-05 | Genentech, Inc. | Il-17 homologous polypeptides and therapeutic uses thereof |
| US7771719B1 (en) | 2000-01-11 | 2010-08-10 | Genentech, Inc. | Pharmaceutical compositions, kits, and therapeutic uses of antagonist antibodies to IL-17E |
| EP1259253A2 (en) * | 2000-02-29 | 2002-11-27 | ZymoGenetics, Inc. | Methods for promoting production of myelin by schwann cells |
| US7718397B2 (en) | 2000-03-21 | 2010-05-18 | Genentech, Inc. | Nucleic acids encoding receptor for IL-17 homologous polypeptides and uses thereof |
| EP1274450B1 (en) * | 2000-04-18 | 2008-12-10 | Schering Corporation | Medical uses of agonsist and antagonists of IL-174 |
| WO2001090358A2 (en) * | 2000-05-24 | 2001-11-29 | Schering Corporation | Mammalian receptor proteins; related reagents and methods |
| US20030096969A1 (en) | 2000-06-02 | 2003-05-22 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| WO2002008259A2 (en) * | 2000-07-26 | 2002-01-31 | Zymogenetics, Inc. | Human cytokine receptor |
| EP1529843A3 (en) * | 2000-08-11 | 2005-06-08 | Eli Lilly & Company | Novel secreted proteins and their uses |
| DE60125563T2 (de) * | 2000-10-13 | 2007-10-04 | Eli Lilly And Co., Indianapolis | Verfahren zur verwendung eines humanen il-17 verwandten polypeptids zur behandlung von krankheiten |
| WO2002038764A2 (en) * | 2000-11-10 | 2002-05-16 | The Regents Of The University Of California | Il-17 receptor-like protein, uses thereof, and modulation of catabolic activity of il-17 cytokines on bone and cartilage |
| US20070160576A1 (en) | 2001-06-05 | 2007-07-12 | Genentech, Inc. | IL-17A/F heterologous polypeptides and therapeutic uses thereof |
| CA2842429A1 (en) * | 2001-10-19 | 2003-05-01 | Genentech, Inc. | Compositions and methods for the diagnosis and treatment of inflammatory bowel disorders |
| US20060281146A1 (en) * | 2002-09-11 | 2006-12-14 | Genetech, Inc. | Novel compositions and methods for the treatment of immune related diseases |
| WO2004047728A2 (en) * | 2002-11-26 | 2004-06-10 | Genentech, Inc. | Compositions and methods for the treatment of immune related diseases |
| AU2004293369A1 (en) * | 2003-03-03 | 2005-06-09 | Genentech, Inc. | Compositions and methods for the treatment of systemic lupus erythematosis |
| AU2004259638C1 (en) | 2003-07-08 | 2018-12-20 | Novartis Pharma Ag | IL-17 A/F heterologous polypeptides and therapeutic uses thereof |
| JP4833850B2 (ja) | 2003-11-21 | 2011-12-07 | ユセベ ファルマ ソシエテ アノニム | Il−17活性阻害による多発性硬化症を治療するための方法 |
| AU2005241020B2 (en) * | 2004-05-03 | 2008-07-10 | Merck Sharp & Dohme Corp. | Use of IL-17 expression to predict skin inflammation; methods of treatment |
| US20050287593A1 (en) | 2004-05-03 | 2005-12-29 | Schering Corporation | Use of cytokine expression to predict skin inflammation; methods of treatment |
| BRPI0511952A (pt) | 2004-06-10 | 2008-01-29 | Zymogenetics Inc | receptor solúvel isolado, anticorpo ou fragmento de anticorpo, e, métodos de reduzir inflamação induzida por il-17a ou induzida por il-17f, de tratar um mamìfero afetado com uma doença inflamatória, e uma condição patológica em um indivìduo associada com atividade de zcytor14 |
| DE602005013805D1 (de) * | 2004-09-21 | 2009-05-20 | Merck Serono Sa Coinsins | Verwendung von il-17f zur behandlung und/oder prävention von neurologischen erkrankungen |
| CA2616831A1 (en) * | 2005-08-04 | 2007-02-15 | Zymogenetics, Inc. | Treatment of wounds using il-17b |
| US20070249533A1 (en) | 2005-09-28 | 2007-10-25 | Levin Steven D | Il-17a and il-17f antagonists and methods of using the same |
| US7622116B2 (en) | 2006-02-10 | 2009-11-24 | Zymogenetics, Inc. | Method of treating inflammation using soluble IL-17RCX4 |
| EP2091968A2 (en) | 2006-10-26 | 2009-08-26 | Novo Nordisk A/S | Il-21 variants |
| WO2008073653A2 (en) * | 2006-11-08 | 2008-06-19 | Zymogenetics, Inc. | Il- 17b for use in wound healing |
| US7790676B2 (en) | 2007-03-28 | 2010-09-07 | Zymogenetics, Inc. | Soluble IL-17RA/RC fusion proteins |
| SG10201608871XA (en) | 2008-05-05 | 2016-12-29 | Novimmune Sa | Anti-il-17a/il-17f cross-reactive antibodies and methods of use thereof |
| US8790642B2 (en) | 2008-08-29 | 2014-07-29 | Genentech, Inc. | Cross-reactive and bispecific anti-IL-17A/F antibodies |
| WO2010103038A1 (en) | 2009-03-11 | 2010-09-16 | Novo Nordisk A/S | Interleukin-21 variants having antagonistic binding to the il-21 receptor |
| SG174891A1 (en) | 2009-04-01 | 2011-11-28 | Genentech Inc | Treatment of insulin-resistant disorders |
| GB0905972D0 (en) * | 2009-04-06 | 2009-05-20 | Medical Res Council | Antibodies against IL-17BR |
| CA2759848C (en) | 2009-05-05 | 2018-12-04 | Novimmune S.A. | Anti-il-17f antibodies and methods of use thereof |
| WO2010142551A2 (en) * | 2009-06-12 | 2010-12-16 | Ablynx N.V. | Single variable domain (vhh) antibodies to cytokines of the il-17 receptor family |
| WO2012098113A1 (en) | 2011-01-17 | 2012-07-26 | Novo Nordisk A/S | Il-21 ligands |
| UA117218C2 (uk) | 2011-05-05 | 2018-07-10 | Мерк Патент Гмбх | Поліпептид, спрямований проти il-17a, il-17f та/або il17-a/f |
| HRP20180776T1 (hr) * | 2011-10-19 | 2018-08-10 | Morphosys Ag | Antagonisti il17c za liječenje upalnih poremećaja |
| JP6236948B2 (ja) * | 2013-07-17 | 2017-11-29 | 東ソー株式会社 | 抗体精製用溶出液および当該溶出液を用いた抗体精製方法 |
| KR20150050921A (ko) * | 2013-11-01 | 2015-05-11 | 현대중공업 주식회사 | 폐열 회수용 연관식 보일러 |
| WO2016070062A2 (en) | 2014-10-31 | 2016-05-06 | Genentech, Inc. | Anti-il-17a and il-17f cross reactive antibody variants and compositions comprising and methods of making and using same |
| EP3250927B1 (en) | 2015-01-28 | 2020-02-19 | H. Hoffnabb-La Roche Ag | Gene expression markers and treatment of multiple sclerosis |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000073452A2 (en) * | 1999-06-02 | 2000-12-07 | Genentech, Inc. | Compositions and methods for the treatment of immune related diseases |
| NZ306653A (en) * | 1995-03-23 | 1999-03-29 | Immunex Corp | Isolated dna il-17 receptors |
| WO2000070050A1 (en) * | 1999-05-14 | 2000-11-23 | Genentech, Inc. | Compositions and methods for the treatment of immune related diseases |
| NZ500885A (en) * | 1997-04-25 | 2001-06-29 | Zymogenetics Inc | Cytokine-like factor 7 (zcyto7) expressed in spinal cord reveals that zcyto7 plays a role in the maintenance of spinal cord involving either glial cells or neurons |
| AU8571198A (en) * | 1997-07-16 | 1999-02-10 | Human Genome Sciences, Inc. | Interleukin-20 |
| US6482923B1 (en) * | 1997-09-17 | 2002-11-19 | Human Genome Sciences, Inc. | Interleukin 17-like receptor protein |
| US6635443B1 (en) * | 1997-09-17 | 2003-10-21 | Human Genome Sciences, Inc. | Polynucleotides encoding a novel interleukin receptor termed interleukin-17 receptor-like protein |
| AU2004799A (en) * | 1997-12-19 | 1999-07-12 | Millennium Biotherapeutics, Inc. | Novel embryo-derived interleukin related factor molecules and uses therefor |
| PT1490386E (pt) * | 1998-03-10 | 2008-11-24 | Genentech Inc | Novos polipéptidos e ácidos nucleicos que os codificam |
| CA2328496C (en) * | 1998-05-15 | 2016-01-05 | Genentech, Inc. | Il-17 homologous polypeptides and therapeutic uses thereof |
| CN1357042A (zh) * | 1999-01-11 | 2002-07-03 | 先灵公司 | 白介素-17相关哺乳动物细胞因子、编码其的多核苷酸、应用 |
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2000
- 2000-12-20 AT AT00989401T patent/ATE444361T1/de active
- 2000-12-20 WO PCT/US2000/034956 patent/WO2001046420A2/en not_active Ceased
- 2000-12-20 AT AT07016903T patent/ATE541931T1/de active
- 2000-12-20 PT PT00989401T patent/PT1240325E/pt unknown
- 2000-12-20 ES ES00989401T patent/ES2333772T3/es not_active Expired - Lifetime
- 2000-12-20 AT AT07016899T patent/ATE537258T1/de active
- 2000-12-20 DK DK00989401.5T patent/DK1240325T3/da active
- 2000-12-20 PT PT07016903T patent/PT1897947E/pt unknown
- 2000-12-20 ES ES10009491.1T patent/ES2458349T3/es not_active Expired - Lifetime
- 2000-12-20 AU AU25909/01A patent/AU2590901A/en not_active Abandoned
- 2000-12-20 ES ES09009972.2T patent/ES2506665T3/es not_active Expired - Lifetime
- 2000-12-20 CA CA002391374A patent/CA2391374A1/en not_active Withdrawn
- 2000-12-20 AT AT07016900T patent/ATE519847T1/de active
- 2000-12-20 ES ES07016902T patent/ES2388748T3/es not_active Expired - Lifetime
- 2000-12-20 PT PT07016900T patent/PT1897944E/pt unknown
- 2000-12-20 ES ES07016899T patent/ES2379101T3/es not_active Expired - Lifetime
- 2000-12-20 PT PT07016901T patent/PT1897945E/pt unknown
- 2000-12-20 ES ES07016901T patent/ES2380958T3/es not_active Expired - Lifetime
- 2000-12-20 EP EP00989401A patent/EP1240325B1/en not_active Expired - Lifetime
- 2000-12-20 AT AT07016901T patent/ATE541930T1/de active
- 2000-12-20 ES ES07016903T patent/ES2380812T3/es not_active Expired - Lifetime
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2008
- 2008-04-21 JP JP2008109843A patent/JP5070117B2/ja not_active Expired - Fee Related
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2009
- 2009-02-04 JP JP2009023863A patent/JP2009159968A/ja active Pending
- 2009-07-22 JP JP2009171169A patent/JP5258691B2/ja not_active Expired - Lifetime
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2010
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2011
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2012
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