ES2319469T3 - Metodo analitico y aparato para el mismo. - Google Patents

Metodo analitico y aparato para el mismo. Download PDF

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Publication number
ES2319469T3
ES2319469T3 ES98942856T ES98942856T ES2319469T3 ES 2319469 T3 ES2319469 T3 ES 2319469T3 ES 98942856 T ES98942856 T ES 98942856T ES 98942856 T ES98942856 T ES 98942856T ES 2319469 T3 ES2319469 T3 ES 2319469T3
Authority
ES
Spain
Prior art keywords
test
mixture
gradient
stream
pka
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES98942856T
Other languages
English (en)
Spanish (es)
Inventor
Christopher David Bevan
Alan Peter Hill
Derek Peter Reynolds
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of ES2319469T3 publication Critical patent/ES2319469T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N31/00—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods
    • G01N31/16—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods using titration
    • G01N31/166—Continuous titration of flowing liquids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/78—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
    • G01N21/79—Photometric titration
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/0068—Means for controlling the apparatus of the process
    • B01J2219/00702—Processes involving means for analysing and characterising the products
    • B01J2219/00707—Processes involving means for analysing and characterising the products separated from the reactor apparatus

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plasma & Fusion (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
ES98942856T 1997-09-09 1998-09-09 Metodo analitico y aparato para el mismo. Expired - Lifetime ES2319469T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9719142 1997-09-09
GBGB9719142.3A GB9719142D0 (en) 1997-09-09 1997-09-09 Analytical method and apparatus therefor

Publications (1)

Publication Number Publication Date
ES2319469T3 true ES2319469T3 (es) 2009-05-07

Family

ID=10818787

Family Applications (1)

Application Number Title Priority Date Filing Date
ES98942856T Expired - Lifetime ES2319469T3 (es) 1997-09-09 1998-09-09 Metodo analitico y aparato para el mismo.

Country Status (12)

Country Link
US (1) US6913930B2 (enExample)
EP (1) EP1012599B1 (enExample)
JP (1) JP2001516054A (enExample)
CN (1) CN1157600C (enExample)
AT (1) ATE420350T1 (enExample)
AU (1) AU742335B2 (enExample)
CA (1) CA2303205C (enExample)
DE (1) DE69840450D1 (enExample)
ES (1) ES2319469T3 (enExample)
GB (1) GB9719142D0 (enExample)
HU (1) HUP0004774A3 (enExample)
WO (1) WO1999013328A1 (enExample)

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* Cited by examiner, † Cited by third party
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EP1250587A1 (en) 2000-01-28 2002-10-23 Pion, Inc. MEASUREMENT OF SOLUBILITY-pH PROFILES
CA2525880C (en) * 2003-05-16 2011-10-11 Cryobiophysica, Inc. External gradient chromatofocusing
US7926024B2 (en) * 2004-06-14 2011-04-12 Hyperformix, Inc. Method and apparatus for managing complex processes
WO2007087433A2 (en) * 2006-01-26 2007-08-02 University Of Montana Titration method using a tracer to quantify the titrant
JP2007263632A (ja) * 2006-03-28 2007-10-11 Miura Co Ltd キレート剤の測定方法およびキレート剤の測定キット
EP2061571A4 (en) * 2006-08-29 2012-06-06 Cryobiophysica Inc INDEPENDENT, SIMULTANEOUS, MULTI-COMPONENT MULTI-GRADIENT SYSTEM FOR LIQUID CHROMATOGRAPHY
JP5151904B2 (ja) * 2008-10-23 2013-02-27 株式会社三菱化学アナリテック 電位差滴定方法および電位差滴定装置
US8382974B2 (en) * 2009-08-18 2013-02-26 Ceramatec, Inc. Sensor to measure a concentration of alkali alcoholate
US8706426B2 (en) 2010-04-16 2014-04-22 University Of Central Florida Research Foundation, Inc. Systems and methods for identifying classes of substances
WO2012011074A2 (en) 2010-07-22 2012-01-26 Hach Company Lab-on-a-chip for alkalinity analysis
US9321851B2 (en) * 2011-03-07 2016-04-26 Hercules Incorporated Water soluble polymer powder formulation having improved dispersing properties
JP5681548B2 (ja) * 2011-03-31 2015-03-11 日本光電工業株式会社 培地溶液のｐＨ計測方法及びｐＨ計測装置
US9180449B2 (en) 2012-06-12 2015-11-10 Hach Company Mobile water analysis
USD768872S1 (en) 2012-12-12 2016-10-11 Hach Company Cuvette for a water analysis instrument
US8921113B2 (en) 2012-12-21 2014-12-30 Dionex Corporation Buffer kit and method of generating a linear pH gradient
CN105301174B (zh) * 2014-07-16 2017-07-18 中国科学院苏州纳米技术与纳米仿生研究所 用于微流控芯片的试剂滴定方法及装置、微流控芯片
KR20160081669A (ko) * 2014-12-31 2016-07-08 삼성전자주식회사 반응 장치, 검사 장치 및 검사 방법
CN105115918A (zh) * 2015-08-12 2015-12-02 泉州装备制造研究所 基于吸收光谱的pH值快速在线检测装置及方法
US10871475B2 (en) * 2017-02-21 2020-12-22 Becs Technology, Inc. Automated titration in a recirculating fluid system
US11231360B2 (en) 2017-06-29 2022-01-25 Hydrite Chemical Co. Automatic titration device
US11397171B2 (en) * 2017-09-18 2022-07-26 Ecolab Usa Inc. Adaptive range flow titration systems and methods with sample conditioning
BR112020020717B1 (pt) * 2018-04-09 2023-10-24 Ecolab Usa Inc Sistema de titulação automatizado, e, método para quantificar uma concentração de analito alvo em uma corrente de amostra
US11397170B2 (en) * 2018-04-16 2022-07-26 Ecolab Usa Inc. Repetition time interval adjustment in adaptive range titration systems and methods
CN110161164A (zh) * 2019-04-16 2019-08-23 大连诚泽检测有限公司 一种流动式化学计量点测定装置及其应用
US11022585B2 (en) 2019-06-09 2021-06-01 Dionex Corporation Methods and systems for optimizing buffer conditions with liquid chromatography
DE102019120415A1 (de) 2019-07-29 2021-02-04 Endress+Hauser Conducta Gmbh+Co. Kg Verfahren zur Bestimmung einer chemischen Aufnahmekapazität eines Prozessmediums in einer Messstelle sowie Messstelle zur Bestimmung einer chemischen Aufnahmekapazität eines Prozessmediums
EP3901621B1 (de) * 2020-04-22 2022-05-04 Safechem Europe GmbH Vorrichtung und verfahren zur bestimmung von flüssigkeitsspezifischen parametern und/oder bestandteilen
CN116440724A (zh) * 2023-04-19 2023-07-18 四川中测标物科技有限公司 一种基于临界流技术的浓度连续可调的稀释装置
CN119619398B (zh) * 2024-12-18 2025-10-14 湖北百杰瑞新材料股份有限公司 测定磷酸二氢锂纯度的方法

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3484170A (en) 1966-04-14 1969-12-16 Technicon Corp Automatic analysis method and apparatus
US3732164A (en) * 1971-08-30 1973-05-08 Administrator Of The Environme Nitrogen removal from waste water by breakpoint chlorination
HU174711B (hu) 1976-04-20 1980-03-28 Egyt Gyogyszervegyeszeti Gyar Sposob i ustrojstvo analiza prob zhidkostej
HUT61104A (en) 1987-03-11 1992-11-30 Gyoergy Horvai Method for potenciometric detecting concentration of a component in a liquid sample
JPS6478164A (en) * 1987-09-19 1989-03-23 Nihon Parkerizing Automatic analysis apparatus for phosphate chemical conversion bath liquid
US4810331A (en) 1987-10-13 1989-03-07 The Clorox Company Surfactant sensing electrode for potentiometric titrations
US5149661A (en) * 1988-06-08 1992-09-22 Sarasep, Inc. Fluid analysis with particulate reagent suspension
US5192509A (en) * 1991-08-22 1993-03-09 Halliburton Company Apparatus for automatic titration
US5447612A (en) * 1993-02-01 1995-09-05 Protein Technologies, Inc. Buffering system and its use in electrophoretic processes

Also Published As

Publication number Publication date
AU9083498A (en) 1999-03-29
GB9719142D0 (en) 1997-11-12
AU742335B2 (en) 2001-12-20
EP1012599A1 (en) 2000-06-28
ATE420350T1 (de) 2009-01-15
HUP0004774A2 (hu) 2001-06-28
EP1012599B1 (en) 2009-01-07
CN1157600C (zh) 2004-07-14
WO1999013328A1 (en) 1999-03-18
CA2303205C (en) 2010-06-01
DE69840450D1 (de) 2009-02-26
HUP0004774A3 (en) 2003-11-28
US6913930B2 (en) 2005-07-05
HK1026479A1 (en) 2000-12-15
CN1278331A (zh) 2000-12-27
CA2303205A1 (en) 1999-03-18
JP2001516054A (ja) 2001-09-25
US20040023405A1 (en) 2004-02-05

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