ES2313978T3 - Proteinas urocortina y sus usos. - Google Patents
Proteinas urocortina y sus usos. Download PDFInfo
- Publication number
- ES2313978T3 ES2313978T3 ES01963759T ES01963759T ES2313978T3 ES 2313978 T3 ES2313978 T3 ES 2313978T3 ES 01963759 T ES01963759 T ES 01963759T ES 01963759 T ES01963759 T ES 01963759T ES 2313978 T3 ES2313978 T3 ES 2313978T3
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- Prior art keywords
- peptide
- urocortin
- seq
- crf
- dna
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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- 201000003995 melancholia Diseases 0.000 description 1
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- 229930182817 methionine Natural products 0.000 description 1
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- PYWVYCXTNDRMGF-UHFFFAOYSA-N rhodamine B Chemical compound [Cl-].C=12C=CC(=[N+](CC)CC)C=C2OC2=CC(N(CC)CC)=CC=C2C=1C1=CC=CC=C1C(O)=O PYWVYCXTNDRMGF-UHFFFAOYSA-N 0.000 description 1
- 239000002336 ribonucleotide Substances 0.000 description 1
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- UQDJGEHQDNVPGU-UHFFFAOYSA-N serine phosphoethanolamine Chemical compound [NH3+]CCOP([O-])(=O)OCC([NH3+])C([O-])=O UQDJGEHQDNVPGU-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/57509—Corticotropin releasing factor [CRF] (Urotensin)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
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- Psychiatry (AREA)
- Molecular Biology (AREA)
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- Endocrinology (AREA)
- Cardiology (AREA)
- Biochemistry (AREA)
- Diabetes (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Wood Science & Technology (AREA)
- Pain & Pain Management (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hospice & Palliative Care (AREA)
- Heart & Thoracic Surgery (AREA)
- General Engineering & Computer Science (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Biotechnology (AREA)
- Child & Adolescent Psychology (AREA)
- Physics & Mathematics (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22325500P | 2000-08-04 | 2000-08-04 | |
| US223255P | 2000-08-04 | ||
| US27396901P | 2001-03-07 | 2001-03-07 | |
| US273969P | 2001-03-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2313978T3 true ES2313978T3 (es) | 2009-03-16 |
Family
ID=26917597
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES01963759T Expired - Lifetime ES2313978T3 (es) | 2000-08-04 | 2001-07-31 | Proteinas urocortina y sus usos. |
Country Status (16)
| Country | Link |
|---|---|
| US (4) | US6838274B2 (enExample) |
| EP (1) | EP1305334B1 (enExample) |
| JP (1) | JP4873825B2 (enExample) |
| KR (1) | KR100879232B1 (enExample) |
| CN (1) | CN1484650B (enExample) |
| AT (1) | ATE408622T1 (enExample) |
| AU (2) | AU2001284683B2 (enExample) |
| CA (1) | CA2418144C (enExample) |
| CY (1) | CY1110424T1 (enExample) |
| DE (1) | DE60135850D1 (enExample) |
| DK (1) | DK1305334T3 (enExample) |
| ES (1) | ES2313978T3 (enExample) |
| IL (2) | IL154102A0 (enExample) |
| PT (1) | PT1305334E (enExample) |
| RU (1) | RU2278871C2 (enExample) |
| WO (1) | WO2002012307A1 (enExample) |
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|---|---|---|---|---|
| IL154102A0 (en) * | 2000-08-04 | 2003-07-31 | Res Dev Foundation | Urocortin proteins and uses thereof |
| US20020082409A1 (en) | 2000-10-26 | 2002-06-27 | Hsu Sheau Yu | Stresscopins and their uses |
| US6670140B2 (en) * | 2001-03-06 | 2003-12-30 | The Procter & Gamble Company | Methods for identifying compounds for regulating muscle mass or function using corticotropin releasing factor receptors |
| AU2002306853B2 (en) | 2001-03-15 | 2006-07-06 | Research Development Foundation | Urocortin-III and uses thereof |
| US7192923B2 (en) | 2002-01-16 | 2007-03-20 | The Procter & Gamble Company | Corticotropin releasing factor 2 receptor agonists |
| WO2008047241A2 (en) * | 2006-10-16 | 2008-04-24 | Conjuchem Biotechnologies Inc. | Modified corticotropin releasing factor peptides and uses thereof |
| EP2522351B1 (en) | 2007-06-13 | 2017-09-06 | Research Development Foundation | Treatment and prevention of tauopathies and amyloid beta amyloidosis by modulating CRF receptor signaling |
| EP2187924A2 (en) * | 2007-09-11 | 2010-05-26 | Mondobiotech Laboratories AG | Use of a peptide as a therapeutic agent |
| WO2009033807A2 (en) * | 2007-09-11 | 2009-03-19 | Mondobiotech Laboratories Ag | Therapeutic uses of b-type natriuretic peptide and human growth hormone 1-43 |
| WO2011025905A1 (en) | 2009-08-28 | 2011-03-03 | Research Development Foundation | Urocortin 2 analogs and uses thereof |
| WO2013063046A1 (en) | 2011-10-24 | 2013-05-02 | Research Development Foundation | Methods for increasing insulin secretion by co-stimulation of corticotropin-releasing factor receptors |
| KR102107482B1 (ko) | 2012-02-14 | 2020-05-08 | 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 | 심혈관 질환 및 다른 증상에 대한 파라크린 유전자의 전신 전달 및 조절 발현 |
| JOP20170153A1 (ar) * | 2016-07-15 | 2019-01-30 | Lilly Co Eli | نظائر urocortin-2 جديدة معدلة بحمض دهني لعلاج داء السكري وأمراض الكلى المزمنة |
| WO2020176807A1 (en) | 2019-02-27 | 2020-09-03 | Vanderbilt University | Methods of treating trigeminal nerve pain |
| CN110826145B (zh) * | 2019-09-09 | 2020-08-28 | 西安工业大学 | 基于超启发式马氏链进化的汽车多参数运行工况设计方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2223792A1 (en) | 1995-06-13 | 1997-01-03 | The Salk Institute For Biological Studies | Urocortin peptides |
| IL154102A0 (en) * | 2000-08-04 | 2003-07-31 | Res Dev Foundation | Urocortin proteins and uses thereof |
| US20020082409A1 (en) | 2000-10-26 | 2002-06-27 | Hsu Sheau Yu | Stresscopins and their uses |
| US6670140B2 (en) * | 2001-03-06 | 2003-12-30 | The Procter & Gamble Company | Methods for identifying compounds for regulating muscle mass or function using corticotropin releasing factor receptors |
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2001
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- 2001-07-31 AT AT01963759T patent/ATE408622T1/de active
- 2001-07-31 CN CN018157831A patent/CN1484650B/zh not_active Expired - Fee Related
- 2001-07-31 JP JP2002518278A patent/JP4873825B2/ja not_active Expired - Fee Related
- 2001-07-31 EP EP01963759A patent/EP1305334B1/en not_active Expired - Lifetime
- 2001-07-31 PT PT01963759T patent/PT1305334E/pt unknown
- 2001-07-31 AU AU2001284683A patent/AU2001284683B2/en not_active Ceased
- 2001-07-31 KR KR1020037001559A patent/KR100879232B1/ko not_active Expired - Fee Related
- 2001-07-31 AU AU8468301A patent/AU8468301A/xx active Pending
- 2001-07-31 DK DK01963759T patent/DK1305334T3/da active
- 2001-07-31 RU RU2003105897/13A patent/RU2278871C2/ru not_active IP Right Cessation
- 2001-07-31 US US09/919,473 patent/US6838274B2/en not_active Expired - Lifetime
- 2001-07-31 DE DE60135850T patent/DE60135850D1/de not_active Expired - Lifetime
- 2001-07-31 CA CA2418144A patent/CA2418144C/en not_active Expired - Fee Related
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- 2001-07-31 ES ES01963759T patent/ES2313978T3/es not_active Expired - Lifetime
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2003
- 2003-01-23 IL IL154102A patent/IL154102A/en not_active IP Right Cessation
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2007
- 2007-04-05 US US11/784,317 patent/US7638607B2/en not_active Expired - Fee Related
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2008
- 2008-12-17 CY CY20081101461T patent/CY1110424T1/el unknown
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2009
- 2009-12-07 US US12/632,715 patent/US8044025B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN1484650A (zh) | 2004-03-24 |
| US7223846B2 (en) | 2007-05-29 |
| KR20030074589A (ko) | 2003-09-19 |
| CA2418144C (en) | 2013-06-18 |
| CY1110424T1 (el) | 2015-04-29 |
| EP1305334A1 (en) | 2003-05-02 |
| IL154102A (en) | 2010-12-30 |
| US7638607B2 (en) | 2009-12-29 |
| US20020127221A1 (en) | 2002-09-12 |
| US8044025B2 (en) | 2011-10-25 |
| PT1305334E (pt) | 2008-12-30 |
| US20070191592A1 (en) | 2007-08-16 |
| US6838274B2 (en) | 2005-01-04 |
| AU2001284683B2 (en) | 2006-04-27 |
| DK1305334T3 (da) | 2009-02-02 |
| ATE408622T1 (de) | 2008-10-15 |
| JP4873825B2 (ja) | 2012-02-08 |
| CN1484650B (zh) | 2012-12-12 |
| DE60135850D1 (de) | 2008-10-30 |
| RU2003105897A (ru) | 2005-01-20 |
| US20050191650A1 (en) | 2005-09-01 |
| EP1305334B1 (en) | 2008-09-17 |
| CA2418144A1 (en) | 2002-02-14 |
| EP1305334A4 (en) | 2005-03-23 |
| KR100879232B1 (ko) | 2009-01-20 |
| IL154102A0 (en) | 2003-07-31 |
| AU8468301A (en) | 2002-02-18 |
| WO2002012307A1 (en) | 2002-02-14 |
| RU2278871C2 (ru) | 2006-06-27 |
| US20100168021A1 (en) | 2010-07-01 |
| JP2004505640A (ja) | 2004-02-26 |
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