ES2308154T3 - Aparato generador de polvo y metodo para producir polvo. - Google Patents
Aparato generador de polvo y metodo para producir polvo. Download PDFInfo
- Publication number
- ES2308154T3 ES2308154T3 ES04714533T ES04714533T ES2308154T3 ES 2308154 T3 ES2308154 T3 ES 2308154T3 ES 04714533 T ES04714533 T ES 04714533T ES 04714533 T ES04714533 T ES 04714533T ES 2308154 T3 ES2308154 T3 ES 2308154T3
- Authority
- ES
- Spain
- Prior art keywords
- reactor
- generating apparatus
- nozzle
- dust generating
- dust
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000843 powder Substances 0.000 title claims abstract description 24
- 238000000034 method Methods 0.000 title claims description 14
- 239000012530 fluid Substances 0.000 claims abstract description 30
- 239000000428 dust Substances 0.000 claims abstract description 17
- 239000003814 drug Substances 0.000 claims abstract description 14
- 238000004519 manufacturing process Methods 0.000 claims abstract description 7
- 239000007788 liquid Substances 0.000 claims description 16
- 238000001035 drying Methods 0.000 claims description 7
- 238000010438 heat treatment Methods 0.000 claims description 7
- 230000015572 biosynthetic process Effects 0.000 claims description 4
- 239000000443 aerosol Substances 0.000 claims description 2
- 239000002245 particle Substances 0.000 description 27
- 229940079593 drug Drugs 0.000 description 11
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 7
- 230000008021 deposition Effects 0.000 description 7
- 239000000243 solution Substances 0.000 description 7
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 6
- 238000009826 distribution Methods 0.000 description 6
- 239000000463 material Substances 0.000 description 6
- 239000000126 substance Substances 0.000 description 6
- 238000000889 atomisation Methods 0.000 description 5
- 239000002904 solvent Substances 0.000 description 5
- 239000007921 spray Substances 0.000 description 4
- 238000005507 spraying Methods 0.000 description 4
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 3
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 3
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
- 238000004581 coalescence Methods 0.000 description 3
- 238000005755 formation reaction Methods 0.000 description 3
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 description 3
- 239000007787 solid Substances 0.000 description 3
- KBPLFHHGFOOTCA-UHFFFAOYSA-N 1-Octanol Chemical compound CCCCCCCCO KBPLFHHGFOOTCA-UHFFFAOYSA-N 0.000 description 2
- LRHPLDYGYMQRHN-UHFFFAOYSA-N N-Butanol Chemical compound CCCCO LRHPLDYGYMQRHN-UHFFFAOYSA-N 0.000 description 2
- IMNFDUFMRHMDMM-UHFFFAOYSA-N N-Heptane Chemical compound CCCCCCC IMNFDUFMRHMDMM-UHFFFAOYSA-N 0.000 description 2
- LQZZUXJYWNFBMV-UHFFFAOYSA-N dodecan-1-ol Chemical compound CCCCCCCCCCCCO LQZZUXJYWNFBMV-UHFFFAOYSA-N 0.000 description 2
- 238000001704 evaporation Methods 0.000 description 2
- 230000008020 evaporation Effects 0.000 description 2
- 229960002848 formoterol Drugs 0.000 description 2
- 230000007721 medicinal effect Effects 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- RYHBNJHYFVUHQT-UHFFFAOYSA-N 1,4-Dioxane Chemical compound C1COCCO1 RYHBNJHYFVUHQT-UHFFFAOYSA-N 0.000 description 1
- VOVIALXJUBGFJZ-KWVAZRHASA-N Budesonide Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@@H]2[C@@H]1[C@@H]1C[C@H]3OC(CCC)O[C@@]3(C(=O)CO)[C@@]1(C)C[C@@H]2O VOVIALXJUBGFJZ-KWVAZRHASA-N 0.000 description 1
- 229910000831 Steel Inorganic materials 0.000 description 1
- 229960004436 budesonide Drugs 0.000 description 1
- 239000000919 ceramic Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 230000005684 electric field Effects 0.000 description 1
- 238000010292 electrical insulation Methods 0.000 description 1
- 238000007590 electrostatic spraying Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- BPZSYCZIITTYBL-UHFFFAOYSA-N formoterol Chemical compound C1=CC(OC)=CC=C1CC(C)NCC(O)C1=CC=C(O)C(NC=O)=C1 BPZSYCZIITTYBL-UHFFFAOYSA-N 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 239000012212 insulator Substances 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 239000007769 metal material Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 230000002940 repellent Effects 0.000 description 1
- 239000005871 repellent Substances 0.000 description 1
- 238000001694 spray drying Methods 0.000 description 1
- 239000010959 steel Substances 0.000 description 1
- 150000003431 steroids Chemical class 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B5/00—Electrostatic spraying apparatus; Spraying apparatus with means for charging the spray electrically; Apparatus for spraying liquids or other fluent materials by other electric means
- B05B5/025—Discharge apparatus, e.g. electrostatic spray guns
- B05B5/0255—Discharge apparatus, e.g. electrostatic spray guns spraying and depositing by electrostatic forces only
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
- B01J2/02—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops
- B01J2/04—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops in a gaseous medium
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B5/00—Electrostatic spraying apparatus; Spraying apparatus with means for charging the spray electrically; Apparatus for spraying liquids or other fluent materials by other electric means
- B05B5/025—Discharge apparatus, e.g. electrostatic spray guns
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
- Processes Of Treating Macromolecular Substances (AREA)
- Glanulating (AREA)
- Electrostatic Spraying Apparatus (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0300514 | 2003-02-26 | ||
| SE0300514A SE0300514D0 (sv) | 2003-02-26 | 2003-02-26 | Powder generating apparatus and methods |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2308154T3 true ES2308154T3 (es) | 2008-12-01 |
Family
ID=20290506
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES04714533T Expired - Lifetime ES2308154T3 (es) | 2003-02-26 | 2004-02-25 | Aparato generador de polvo y metodo para producir polvo. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20060150901A1 (enExample) |
| EP (1) | EP1603665B1 (enExample) |
| JP (1) | JP2006519687A (enExample) |
| AT (1) | ATE399591T1 (enExample) |
| DE (1) | DE602004014742D1 (enExample) |
| ES (1) | ES2308154T3 (enExample) |
| SE (1) | SE0300514D0 (enExample) |
| WO (1) | WO2004076057A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4690418B2 (ja) * | 2004-11-10 | 2011-06-01 | ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン | 多相ナノ粒子 |
| NL1033253C2 (nl) | 2007-01-18 | 2008-07-22 | Stichting Wetsus Ct Of Excellence | Werkwijze en inrichting voor het zuiveren van een vloeistof. |
| GB0713876D0 (en) * | 2007-07-18 | 2007-08-29 | 3M Innovative Properties Co | Manufacture of components for medicinal dispensers |
| WO2012087350A2 (en) * | 2010-12-21 | 2012-06-28 | President And Fellows Of Harvard College | Spray drying techniques |
| EP2665559B1 (en) * | 2011-01-19 | 2018-07-18 | Washington University | Electrohydrodynamic atomization nozzle emitting a liquid sheet |
| TW201540772A (zh) * | 2014-04-24 | 2015-11-01 | 美樺興業股份有限公司 | 高分子粒子及其製備方法 |
| JP6459660B2 (ja) * | 2015-03-12 | 2019-01-30 | 日本ゼオン株式会社 | 造粒装置及び複合粒子の製造方法 |
| CN107028765A (zh) * | 2017-05-05 | 2017-08-11 | 盐城卫生职业技术学院 | 药物加工装置和药物处理装置 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4264641A (en) * | 1977-03-17 | 1981-04-28 | Phrasor Technology Inc. | Electrohydrodynamic spraying to produce ultrafine particles |
| DE3533954A1 (de) * | 1985-09-24 | 1987-03-26 | Agfa Gevaert Ag | Automatisch be- und entladbare roentgenfilmkassette und hierfuer geeignetes roentgenfilmkassettenbe- und -entladegeraet |
| GB8604328D0 (en) * | 1986-02-21 | 1986-03-26 | Ici Plc | Producing spray of droplets of liquid |
| US4748043A (en) * | 1986-08-29 | 1988-05-31 | Minnesota Mining And Manufacturing Company | Electrospray coating process |
| US4762553A (en) * | 1987-04-24 | 1988-08-09 | The United States Of America As Represented By The Secretary Of The Air Force | Method for making rapidly solidified powder |
| GB2206575B (en) * | 1987-07-09 | 1992-01-02 | Glaverbel | Spherulizing furnace and process of manufacturing vitreous beads |
| US5503372A (en) * | 1989-11-27 | 1996-04-02 | Martin Marietta Energy Systems, Inc. | Nozzle for electric dispersion reactor |
| US5015845A (en) * | 1990-06-01 | 1991-05-14 | Vestec Corporation | Electrospray method for mass spectrometry |
| US5344676A (en) * | 1992-10-23 | 1994-09-06 | The Board Of Trustees Of The University Of Illinois | Method and apparatus for producing nanodrops and nanoparticles and thin film deposits therefrom |
| NL1003442C2 (nl) * | 1996-06-27 | 1998-01-07 | Univ Delft Tech | Werkwijze voor het bereiden van een poeder, een met de genoemde werkwijze bereid poeder, een elektrode en een inrichting voor toepassing bij de genoemde werkwijze. |
| US6001336A (en) * | 1996-12-31 | 1999-12-14 | Inhale Therapeutic Systems | Processes for spray drying aqueous suspensions of hydrophobic drugs and compositions thereof |
| US6433154B1 (en) * | 1997-06-12 | 2002-08-13 | Bristol-Myers Squibb Company | Functional receptor/kinase chimera in yeast cells |
| GB2345010B (en) * | 1998-12-17 | 2002-12-31 | Electrosols Ltd | A delivery device |
| CN1400934A (zh) * | 2000-02-18 | 2003-03-05 | 冲激注射技术股份有限公司 | 制造纤维的方法和设备 |
| EP1282470B1 (en) * | 2000-05-16 | 2008-08-20 | Regents Of The University Of Minnesota | High mass throughput particle generation using multiple nozzle spraying |
| KR100394371B1 (ko) * | 2000-09-22 | 2003-08-09 | 주식회사 에이스랩 | 초미세입자를 이용한 정전기 제어장치 |
| SE0101478D0 (sv) * | 2001-04-25 | 2001-04-25 | Astrazeneca Ab | Fluid dispensing apparatus and methods |
-
2003
- 2003-02-26 SE SE0300514A patent/SE0300514D0/xx unknown
-
2004
- 2004-02-25 US US10/546,636 patent/US20060150901A1/en not_active Abandoned
- 2004-02-25 AT AT04714533T patent/ATE399591T1/de not_active IP Right Cessation
- 2004-02-25 EP EP04714533A patent/EP1603665B1/en not_active Expired - Lifetime
- 2004-02-25 DE DE602004014742T patent/DE602004014742D1/de not_active Expired - Fee Related
- 2004-02-25 ES ES04714533T patent/ES2308154T3/es not_active Expired - Lifetime
- 2004-02-25 JP JP2006502813A patent/JP2006519687A/ja active Pending
- 2004-02-25 WO PCT/SE2004/000246 patent/WO2004076057A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| US20060150901A1 (en) | 2006-07-13 |
| EP1603665A1 (en) | 2005-12-14 |
| JP2006519687A (ja) | 2006-08-31 |
| DE602004014742D1 (de) | 2008-08-14 |
| ATE399591T1 (de) | 2008-07-15 |
| SE0300514D0 (sv) | 2003-02-26 |
| EP1603665B1 (en) | 2008-07-02 |
| WO2004076057A1 (en) | 2004-09-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US7849850B2 (en) | Nozzle for handheld pulmonary aerosol delivery device | |
| ES2236531T3 (es) | Dispositivo de atomizacion electrostatico. | |
| JP4677102B2 (ja) | エーロゾル給送装置及びエーロゾル小滴を給送する方法 | |
| Yurteri et al. | Producing pharmaceutical particles via electrospraying with an emphasis on nano and nano structured particles-A review | |
| KR100289783B1 (ko) | 분무장치 | |
| EP2800634B1 (en) | System and method for delivering sprayed particles by electrospraying | |
| US7360724B2 (en) | Electrostatic spray nozzle with internal and external electrodes | |
| ES2308154T3 (es) | Aparato generador de polvo y metodo para producir polvo. | |
| JPH05501676A (ja) | 電子ビームを使用した流動性物質の分散方法及びその装置 | |
| JPS646821B2 (enExample) | ||
| NL2014402B1 (en) | Tailored nano-meso particles. | |
| KR101263591B1 (ko) | 콘젯 모드 정전기 스프레이 장치 | |
| WO2002085530A1 (en) | Fluid dispensing apparatus and methods | |
| CN117983434A (zh) | 静电雾化系统 | |
| HK1203441B (en) | System and method for delivering sprayed particles by electrospraying | |
| ES2239861A1 (es) | Dispositivo y procedimiento para la dispersion electrohidrodinamica de un liquido conductor en un baño dielectrico. | |
| HK1064063B (en) | Electrostatic atomisation device |