ES2278414T3 - Sistemas y metodos para obtener celulas mononucleares mediante recirculacion de paquetes de globulos rojos. - Google Patents
Sistemas y metodos para obtener celulas mononucleares mediante recirculacion de paquetes de globulos rojos. Download PDFInfo
- Publication number
- ES2278414T3 ES2278414T3 ES98934139T ES98934139T ES2278414T3 ES 2278414 T3 ES2278414 T3 ES 2278414T3 ES 98934139 T ES98934139 T ES 98934139T ES 98934139 T ES98934139 T ES 98934139T ES 2278414 T3 ES2278414 T3 ES 2278414T3
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- Spain
- Prior art keywords
- chamber
- interface
- during
- red blood
- controller
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 210000005087 mononuclear cell Anatomy 0.000 title claims abstract description 33
- 238000000034 method Methods 0.000 title claims description 63
- 210000004369 blood Anatomy 0.000 claims abstract description 90
- 239000008280 blood Substances 0.000 claims abstract description 90
- 230000032258 transport Effects 0.000 claims abstract description 38
- 210000003743 erythrocyte Anatomy 0.000 claims abstract description 36
- 238000000926 separation method Methods 0.000 claims abstract description 30
- 238000012545 processing Methods 0.000 claims description 103
- 239000000470 constituent Substances 0.000 claims description 15
- 230000008030 elimination Effects 0.000 claims description 12
- 238000003379 elimination reaction Methods 0.000 claims description 12
- 210000004027 cell Anatomy 0.000 claims description 8
- 230000004044 response Effects 0.000 claims description 4
- 210000002381 plasma Anatomy 0.000 abstract description 29
- 238000001514 detection method Methods 0.000 abstract description 6
- 238000005119 centrifugation Methods 0.000 abstract description 3
- 210000004623 platelet-rich plasma Anatomy 0.000 description 87
- 239000012530 fluid Substances 0.000 description 65
- 210000001772 blood platelet Anatomy 0.000 description 27
- 238000005534 hematocrit Methods 0.000 description 27
- 230000003287 optical effect Effects 0.000 description 25
- 238000005086 pumping Methods 0.000 description 24
- 238000003306 harvesting Methods 0.000 description 21
- 239000007788 liquid Substances 0.000 description 20
- 238000004140 cleaning Methods 0.000 description 13
- 230000037452 priming Effects 0.000 description 13
- 239000000725 suspension Substances 0.000 description 13
- 238000009825 accumulation Methods 0.000 description 11
- 230000002572 peristaltic effect Effects 0.000 description 9
- 230000007704 transition Effects 0.000 description 9
- 210000003714 granulocyte Anatomy 0.000 description 6
- 230000005540 biological transmission Effects 0.000 description 5
- 230000008569 process Effects 0.000 description 5
- 230000003134 recirculating effect Effects 0.000 description 5
- 238000010790 dilution Methods 0.000 description 4
- 239000012895 dilution Substances 0.000 description 4
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 3
- 239000003146 anticoagulant agent Substances 0.000 description 3
- 229940127219 anticoagulant drug Drugs 0.000 description 3
- 230000004888 barrier function Effects 0.000 description 3
- 210000000601 blood cell Anatomy 0.000 description 3
- 238000004364 calculation method Methods 0.000 description 3
- 238000004891 communication Methods 0.000 description 3
- 230000012953 feeding on blood of other organism Effects 0.000 description 3
- 230000007246 mechanism Effects 0.000 description 3
- 238000011144 upstream manufacturing Methods 0.000 description 3
- 230000001133 acceleration Effects 0.000 description 2
- 238000011072 cell harvest Methods 0.000 description 2
- 230000008878 coupling Effects 0.000 description 2
- 238000010168 coupling process Methods 0.000 description 2
- 238000005859 coupling reaction Methods 0.000 description 2
- 238000005520 cutting process Methods 0.000 description 2
- 230000006870 function Effects 0.000 description 2
- 230000004941 influx Effects 0.000 description 2
- 238000001802 infusion Methods 0.000 description 2
- 210000004698 lymphocyte Anatomy 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 210000001616 monocyte Anatomy 0.000 description 2
- 229920003023 plastic Polymers 0.000 description 2
- 238000007781 pre-processing Methods 0.000 description 2
- 239000002699 waste material Substances 0.000 description 2
- 241000557626 Corvus corax Species 0.000 description 1
- 241001343277 Entada Species 0.000 description 1
- 102000001554 Hemoglobins Human genes 0.000 description 1
- 108010054147 Hemoglobins Proteins 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 230000001413 cellular effect Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 229920002457 flexible plastic Polymers 0.000 description 1
- 238000007667 floating Methods 0.000 description 1
- 230000014509 gene expression Effects 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 210000000265 leukocyte Anatomy 0.000 description 1
- 238000012417 linear regression Methods 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 238000004062 sedimentation Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D21/00—Separation of suspended solid particles from liquids by sedimentation
- B01D21/30—Control equipment
- B01D21/302—Active control mechanisms with external energy, e.g. with solenoid valve
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3601—Extra-corporeal circuits in which the blood fluid passes more than once through the treatment unit
- A61M1/3603—Extra-corporeal circuits in which the blood fluid passes more than once through the treatment unit in the same direction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
- A61M1/3622—Extra-corporeal blood circuits with a cassette forming partially or totally the blood circuit
- A61M1/36222—Details related to the interface between cassette and machine
- A61M1/362227—Details related to the interface between cassette and machine the interface providing means for actuating on functional elements of the cassette, e.g. plungers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
- A61M1/3622—Extra-corporeal blood circuits with a cassette forming partially or totally the blood circuit
- A61M1/36225—Extra-corporeal blood circuits with a cassette forming partially or totally the blood circuit with blood pumping means or components thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
- A61M1/3622—Extra-corporeal blood circuits with a cassette forming partially or totally the blood circuit
- A61M1/36226—Constructional details of cassettes, e.g. specific details on material or shape
- A61M1/362261—Constructional details of cassettes, e.g. specific details on material or shape at least one cassette surface or portion thereof being flexible, e.g. the cassette having a rigid base portion with preformed channels and being covered with a foil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
- A61M1/3622—Extra-corporeal blood circuits with a cassette forming partially or totally the blood circuit
- A61M1/36226—Constructional details of cassettes, e.g. specific details on material or shape
- A61M1/362265—Details of valves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
- A61M1/3622—Extra-corporeal blood circuits with a cassette forming partially or totally the blood circuit
- A61M1/36226—Constructional details of cassettes, e.g. specific details on material or shape
- A61M1/362266—Means for adding solutions or substances to the blood
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
- A61M1/3696—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D21/00—Separation of suspended solid particles from liquids by sedimentation
- B01D21/26—Separation of sediment aided by centrifugal force or centripetal force
- B01D21/262—Separation of sediment aided by centrifugal force or centripetal force by using a centrifuge
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
- B04B—CENTRIFUGES
- B04B13/00—Control arrangements specially designed for centrifuges; Programme control of centrifuges
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
- B04B—CENTRIFUGES
- B04B5/00—Other centrifuges
- B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
- B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2221/00—Applications of separation devices
- B01D2221/10—Separation devices for use in medical, pharmaceutical or laboratory applications, e.g. separating amalgam from dental treatment residues
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
- B04B—CENTRIFUGES
- B04B5/00—Other centrifuges
- B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
- B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
- B04B2005/045—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation having annular separation channels
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
- B04B—CENTRIFUGES
- B04B13/00—Control arrangements specially designed for centrifuges; Programme control of centrifuges
- B04B2013/006—Interface detection or monitoring of separated components
Landscapes
- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Public Health (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- External Artificial Organs (AREA)
- Centrifugal Separators (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/886,780 US5980760A (en) | 1997-07-01 | 1997-07-01 | System and methods for harvesting mononuclear cells by recirculation of packed red blood cells |
| US886780 | 1997-07-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2278414T3 true ES2278414T3 (es) | 2007-08-01 |
Family
ID=25389755
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES98934139T Expired - Lifetime ES2278414T3 (es) | 1997-07-01 | 1998-06-22 | Sistemas y metodos para obtener celulas mononucleares mediante recirculacion de paquetes de globulos rojos. |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5980760A (enExample) |
| EP (1) | EP1003609B1 (enExample) |
| JP (1) | JP4076588B2 (enExample) |
| CN (1) | CN1113702C (enExample) |
| BR (1) | BR9810649A (enExample) |
| CA (1) | CA2293298A1 (enExample) |
| DE (1) | DE69836586T2 (enExample) |
| ES (1) | ES2278414T3 (enExample) |
| WO (1) | WO1999001225A1 (enExample) |
Families Citing this family (69)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5958250A (en) * | 1995-06-07 | 1999-09-28 | Baxter International Inc. | Blood processing systems and methods which optically derive the volume of platelets contained in a plasma constituent |
| US6312607B1 (en) | 1995-06-07 | 2001-11-06 | Baxter International Inc. | Blood processing systems and methods which optically monitor incremental platelet volumes in a plasma constituent |
| US6254784B1 (en) * | 1997-10-30 | 2001-07-03 | Baxter International Inc. | Optical interface detection system for centrifugal blood processing |
| JP3196838B2 (ja) * | 1998-09-11 | 2001-08-06 | ヘモネティクス・コーポレーション | アフェレーシス装置及び血液製剤の製造方法 |
| US6524231B1 (en) | 1999-09-03 | 2003-02-25 | Baxter International Inc. | Blood separation chamber with constricted interior channel and recessed passage |
| US6315707B1 (en) | 1999-09-03 | 2001-11-13 | Baxter International Inc. | Systems and methods for seperating blood in a rotating field |
| US6294094B1 (en) | 1999-09-03 | 2001-09-25 | Baxter International Inc. | Systems and methods for sensing red blood cell hematocrit |
| US6348156B1 (en) | 1999-09-03 | 2002-02-19 | Baxter International Inc. | Blood processing systems and methods with sensors to detect contamination due to presence of cellular components or dilution due to presence of plasma |
| US6322488B1 (en) * | 1999-09-03 | 2001-11-27 | Baxter International Inc. | Blood separation chamber with preformed blood flow passages and centralized connection to external tubing |
| US6860846B2 (en) * | 1999-09-03 | 2005-03-01 | Baxter International Inc. | Blood processing systems and methods with umbilicus-driven blood processing chambers |
| US6284142B1 (en) | 1999-09-03 | 2001-09-04 | Baxter International Inc. | Sensing systems and methods for differentiating between different cellular blood species during extracorporeal blood separation or processing |
| US7011761B2 (en) * | 1999-09-03 | 2006-03-14 | Baxter International Inc. | Red blood cell processing systems and methods which control red blood cell hematocrit |
| US20020077241A1 (en) * | 1999-09-03 | 2002-06-20 | Baxter International Inc. | Blood processing systems and methods with quick attachment of a blood separation chamber to a centrifuge rotor |
| US6730054B2 (en) * | 1999-10-16 | 2004-05-04 | Baxter International Inc. | Blood collection systems and methods that derive estimated effects upon the donor's blood volume and hematocrit |
| US6466879B1 (en) * | 2000-07-13 | 2002-10-15 | Baxter International Inc. | Systems and methods for monitoring introduction of a processing fluid during a fluid processing procedure |
| US6706008B2 (en) | 2001-03-06 | 2004-03-16 | Baxter International Inc. | Automated system and method for withdrawing compounds from blood |
| US6808503B2 (en) | 2001-03-06 | 2004-10-26 | Baxter International Inc. | Automated system and method for pre-surgical blood donation and fluid replacement |
| US6582386B2 (en) | 2001-03-06 | 2003-06-24 | Baxter International Inc. | Multi-purpose, automated blood and fluid processing systems and methods |
| US6884228B2 (en) | 2001-03-06 | 2005-04-26 | Baxter International Inc. | Automated system adaptable for use with different fluid circuits |
| US6890291B2 (en) | 2001-06-25 | 2005-05-10 | Mission Medical, Inc. | Integrated automatic blood collection and processing unit |
| US6878105B2 (en) | 2001-08-16 | 2005-04-12 | Baxter International Inc. | Red blood cell processing systems and methods with deliberate under spill of red blood cells |
| JP3997890B2 (ja) * | 2001-11-13 | 2007-10-24 | 松下電器産業株式会社 | 送信方法及び送信装置 |
| US7479123B2 (en) | 2002-03-04 | 2009-01-20 | Therakos, Inc. | Method for collecting a desired blood component and performing a photopheresis treatment |
| US7186230B2 (en) * | 2002-03-04 | 2007-03-06 | Therakos, Inc | Method and apparatus for the continuous separation of biological fluids into components |
| US7211037B2 (en) | 2002-03-04 | 2007-05-01 | Therakos, Inc. | Apparatus for the continuous separation of biological fluids into components and method of using same |
| WO2003089926A2 (en) | 2002-04-19 | 2003-10-30 | Mission Medical, Inc. | Integrated automatic blood processing unit |
| US6982038B2 (en) | 2002-06-14 | 2006-01-03 | Medtronic, Inc. | Centrifuge system utilizing disposable components and automated processing of blood to collect platelet rich plasma |
| US6849039B2 (en) * | 2002-10-24 | 2005-02-01 | Baxter International Inc. | Blood processing systems and methods for collecting plasma free or essentially free of cellular blood components |
| US7297272B2 (en) * | 2002-10-24 | 2007-11-20 | Fenwal, Inc. | Separation apparatus and method |
| US7476209B2 (en) | 2004-12-21 | 2009-01-13 | Therakos, Inc. | Method and apparatus for collecting a blood component and performing a photopheresis treatment |
| US8628489B2 (en) | 2008-04-14 | 2014-01-14 | Haemonetics Corporation | Three-line apheresis system and method |
| US8454548B2 (en) | 2008-04-14 | 2013-06-04 | Haemonetics Corporation | System and method for plasma reduced platelet collection |
| US8702637B2 (en) | 2008-04-14 | 2014-04-22 | Haemonetics Corporation | System and method for optimized apheresis draw and return |
| US8834402B2 (en) | 2009-03-12 | 2014-09-16 | Haemonetics Corporation | System and method for the re-anticoagulation of platelet rich plasma |
| FI123500B (fi) | 2009-09-25 | 2013-06-14 | Metso Paper Inc | Järjestely kuiturainan kiinnirullaimen yhteydessä |
| JP5490966B2 (ja) | 2010-11-05 | 2014-05-14 | ヘモネティクス・コーポレーション | 自動化された血小板洗浄のためのシステムおよび方法 |
| US20220031925A1 (en) | 2010-11-19 | 2022-02-03 | Dsm Ip Assets B.V. | Centrifuge |
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| US9302042B2 (en) | 2010-12-30 | 2016-04-05 | Haemonetics Corporation | System and method for collecting platelets and anticipating plasma return |
| US11386993B2 (en) | 2011-05-18 | 2022-07-12 | Fenwal, Inc. | Plasma collection with remote programming |
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| CN111494743B (zh) | 2012-09-04 | 2023-08-22 | 汾沃有限公司 | 血液处理系统和在血液处理系统内监测流体的方法 |
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| US11383015B2 (en) * | 2016-01-11 | 2022-07-12 | Fenwal, Inc. | System and method for plasma purification prior to mononuclear cell collection |
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| CN106890373A (zh) * | 2017-02-10 | 2017-06-27 | 广州上诺生物技术有限公司 | 一种用于数字化管理血浆过滤白细胞的方法及系统 |
| EP3372259B1 (en) | 2017-03-07 | 2022-11-23 | Fenwal, Inc. | System and methods for separating blood under conditions of reduced plasma clarity |
| US10792416B2 (en) | 2017-05-30 | 2020-10-06 | Haemonetics Corporation | System and method for collecting plasma |
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| US10561784B2 (en) | 2017-05-31 | 2020-02-18 | Fenwal, Inc. | Stationary optical monitoring system for blood processing system |
| EP3501562B1 (en) | 2017-12-22 | 2025-02-05 | Fenwal, Inc. | Convertible fluid processing assemblies |
| CA3088016A1 (en) | 2018-01-22 | 2019-07-25 | Scinogy Products Pty Ltd | System, method and controller for recovery of concentrated particles suspended in fluid |
| EP3553498B1 (en) | 2018-04-13 | 2021-06-02 | Fenwal, Inc. | Optical detection and measurement of hematocrit and free hemoglobin concentration |
| US12033750B2 (en) | 2018-05-21 | 2024-07-09 | Fenwal, Inc. | Plasma collection |
| CN112105403B (zh) | 2018-05-21 | 2022-08-09 | 汾沃有限公司 | 用于对血浆采集体积进行优化的系统和方法 |
| US11412967B2 (en) | 2018-05-21 | 2022-08-16 | Fenwal, Inc. | Systems and methods for plasma collection |
| US10890524B2 (en) | 2018-06-05 | 2021-01-12 | Fenwal, Inc. | Discerning between the presence of red blood cells and free hemoglobin in a biological fluid |
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-
1997
- 1997-07-01 US US08/886,780 patent/US5980760A/en not_active Expired - Lifetime
-
1998
- 1998-06-22 CA CA002293298A patent/CA2293298A1/en not_active Abandoned
- 1998-06-22 ES ES98934139T patent/ES2278414T3/es not_active Expired - Lifetime
- 1998-06-22 WO PCT/US1998/012172 patent/WO1999001225A1/en not_active Ceased
- 1998-06-22 JP JP50866599A patent/JP4076588B2/ja not_active Expired - Fee Related
- 1998-06-22 BR BR9810649-0A patent/BR9810649A/pt not_active IP Right Cessation
- 1998-06-22 DE DE69836586T patent/DE69836586T2/de not_active Expired - Lifetime
- 1998-06-22 EP EP98934139A patent/EP1003609B1/en not_active Expired - Lifetime
- 1998-06-22 CN CN98806828A patent/CN1113702C/zh not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US5980760A (en) | 1999-11-09 |
| DE69836586D1 (de) | 2007-01-18 |
| WO1999001225A1 (en) | 1999-01-14 |
| CN1268075A (zh) | 2000-09-27 |
| EP1003609B1 (en) | 2006-12-06 |
| CN1113702C (zh) | 2003-07-09 |
| EP1003609A1 (en) | 2000-05-31 |
| CA2293298A1 (en) | 1999-01-14 |
| DE69836586T2 (de) | 2007-09-13 |
| JP4076588B2 (ja) | 2008-04-16 |
| EP1003609A4 (en) | 2004-12-15 |
| BR9810649A (pt) | 2000-10-03 |
| JP2002511785A (ja) | 2002-04-16 |
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