ES2200678B1 - Uso de la proteina mal como marcador tumoral. - Google Patents
Uso de la proteina mal como marcador tumoral.Info
- Publication number
- ES2200678B1 ES2200678B1 ES200200615A ES200200615A ES2200678B1 ES 2200678 B1 ES2200678 B1 ES 2200678B1 ES 200200615 A ES200200615 A ES 200200615A ES 200200615 A ES200200615 A ES 200200615A ES 2200678 B1 ES2200678 B1 ES 2200678B1
- Authority
- ES
- Spain
- Prior art keywords
- protein
- marker
- tumor marker
- bad protein
- bad
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
- G01N33/57492—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds localized on the membrane of tumor or cancer cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57438—Specifically defined cancers of liver, pancreas or kidney
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/577—Immunoassay; Biospecific binding assay; Materials therefor involving monoclonal antibodies binding reaction mechanisms characterised by the use of monoclonal antibodies; monoclonal antibodies per se are classified with their corresponding antigens
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Cell Biology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Organic Chemistry (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Veterinary Medicine (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Toxicology (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Uso de la proteína MAL como marcador tumoral. La invención presente presenta la utilización de la proteína mal como un nuevo marcador y diana molecular en tumores epiteliales y otras patologías humanas. En concreto forma parte de la presente invención el uso de la detección de la proteína MAL como marcador con fines diagnósticos o pronósticos para tumores u otras patologías que afecten a células epiteliales, linfocitos T, mastocitos, células formadora de mielina o otros tipos celulares que normalmente expresen la proteína MAL.
Priority Applications (11)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES200200615A ES2200678B1 (es) | 2002-03-14 | 2002-03-14 | Uso de la proteina mal como marcador tumoral. |
EP03712142A EP1930728A1 (en) | 2002-03-14 | 2003-03-14 | Use of the mal protein as a tumour marker |
MXPA04008962A MXPA04008962A (es) | 2002-03-14 | 2003-03-14 | Uso de la proteina mal como marcador tumoral. |
AU2003216926A AU2003216926A1 (en) | 2002-03-14 | 2003-03-14 | Use of the mal protein as a tumour marker |
IL16357803A IL163578A0 (en) | 2002-03-14 | 2003-03-14 | Use of the mal protein as a tumour marker |
JP2003575121A JP2005520135A (ja) | 2002-03-14 | 2003-03-14 | 腫瘍マーカーとしてのmalタンパク質の使用 |
KR10-2004-7014489A KR20040105771A (ko) | 2002-03-14 | 2003-03-14 | Mal 단백질을 종양 표지자로 사용하는 방법 |
PCT/ES2003/000119 WO2003076948A1 (es) | 2002-03-14 | 2003-03-14 | Uso de la proteina mal como marcador tumoral |
CNA038057565A CN1643380A (zh) | 2002-03-14 | 2003-03-14 | 将mal蛋白作为肿瘤标记的应用 |
RU2004129773/15A RU2004129773A (ru) | 2002-03-14 | 2003-03-14 | Использование белка mal в качестве опухолевого маркера |
CA002476767A CA2476767A1 (en) | 2002-03-14 | 2003-03-14 | Use of the mal protein as a tumour marker |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES200200615A ES2200678B1 (es) | 2002-03-14 | 2002-03-14 | Uso de la proteina mal como marcador tumoral. |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2200678A1 ES2200678A1 (es) | 2004-03-01 |
ES2200678B1 true ES2200678B1 (es) | 2005-06-01 |
Family
ID=27799028
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES200200615A Expired - Fee Related ES2200678B1 (es) | 2002-03-14 | 2002-03-14 | Uso de la proteina mal como marcador tumoral. |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP1930728A1 (es) |
JP (1) | JP2005520135A (es) |
KR (1) | KR20040105771A (es) |
CN (1) | CN1643380A (es) |
AU (1) | AU2003216926A1 (es) |
CA (1) | CA2476767A1 (es) |
ES (1) | ES2200678B1 (es) |
IL (1) | IL163578A0 (es) |
MX (1) | MXPA04008962A (es) |
RU (1) | RU2004129773A (es) |
WO (1) | WO2003076948A1 (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111295394B (zh) | 2017-08-11 | 2024-06-11 | 豪夫迈·罗氏有限公司 | 抗cd8抗体及其用途 |
JP2022517917A (ja) * | 2018-12-28 | 2022-03-11 | ネオゼンティーシー コーポレーション | Malが発現された幹細胞様メモリーt細胞を有効成分として含む免疫増強又は抗癌活性促進用の組成物 |
EP3903805A4 (en) * | 2018-12-28 | 2022-09-14 | Neogentc Corp. (Convergence Innovation Building, Asan Institute for Life Sciences, Pungnap-dong) | COMPOSITION OF OR ENHANCEMENT OF ANTI-CANCER OR IMMUNOSTIMULATING ACTIVITY COMPRISING A MAL-EXPRESSED STEM CELL-LIKE MEMORY T CELL AS AN ACTIVE INGREDIENT |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2003532383A (ja) * | 2000-01-18 | 2003-11-05 | ヒューマン ジノーム サイエンシーズ, インコーポレイテッド | ヒトポリヌクレオチド、ポリペプチド、および抗体 |
-
2002
- 2002-03-14 ES ES200200615A patent/ES2200678B1/es not_active Expired - Fee Related
-
2003
- 2003-03-14 MX MXPA04008962A patent/MXPA04008962A/es not_active Application Discontinuation
- 2003-03-14 CN CNA038057565A patent/CN1643380A/zh active Pending
- 2003-03-14 EP EP03712142A patent/EP1930728A1/en not_active Withdrawn
- 2003-03-14 IL IL16357803A patent/IL163578A0/xx unknown
- 2003-03-14 AU AU2003216926A patent/AU2003216926A1/en not_active Abandoned
- 2003-03-14 KR KR10-2004-7014489A patent/KR20040105771A/ko not_active Application Discontinuation
- 2003-03-14 CA CA002476767A patent/CA2476767A1/en not_active Abandoned
- 2003-03-14 WO PCT/ES2003/000119 patent/WO2003076948A1/es active Application Filing
- 2003-03-14 JP JP2003575121A patent/JP2005520135A/ja active Pending
- 2003-03-14 RU RU2004129773/15A patent/RU2004129773A/ru not_active Application Discontinuation
Non-Patent Citations (4)
Also Published As
Publication number | Publication date |
---|---|
KR20040105771A (ko) | 2004-12-16 |
IL163578A0 (en) | 2005-12-18 |
RU2004129773A (ru) | 2005-05-10 |
CA2476767A1 (en) | 2003-09-18 |
AU2003216926A1 (en) | 2003-09-22 |
JP2005520135A (ja) | 2005-07-07 |
CN1643380A (zh) | 2005-07-20 |
EP1930728A1 (en) | 2008-06-11 |
ES2200678A1 (es) | 2004-03-01 |
MXPA04008962A (es) | 2005-06-03 |
WO2003076948A1 (es) | 2003-09-18 |
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Legal Events
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Date of ref document: 20040301 Kind code of ref document: A1 |
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