ES2195122T3 - Inhibidores de metaloproteinasa. - Google Patents

Inhibidores de metaloproteinasa.

Info

Publication number
ES2195122T3
ES2195122T3 ES97912351T ES97912351T ES2195122T3 ES 2195122 T3 ES2195122 T3 ES 2195122T3 ES 97912351 T ES97912351 T ES 97912351T ES 97912351 T ES97912351 T ES 97912351T ES 2195122 T3 ES2195122 T3 ES 2195122T3
Authority
ES
Spain
Prior art keywords
metaloproteinase inhibitors
metaloproteinase
inhibitors
succinamide
carbamoyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97912351T
Other languages
English (en)
Spanish (es)
Inventor
Raymond Paul Beckett
Mark Whittaker
Andrew Miller
Fionna Mitchell Martin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vernalis R&D Ltd
Original Assignee
British Biotech Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by British Biotech Pharmaceuticals Ltd filed Critical British Biotech Pharmaceuticals Ltd
Application granted granted Critical
Publication of ES2195122T3 publication Critical patent/ES2195122T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/75Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4402Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Lubricants (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Saccharide Compounds (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ES97912351T 1997-11-13 1997-11-13 Inhibidores de metaloproteinasa. Expired - Lifetime ES2195122T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/GB1997/003132 WO1999025693A1 (en) 1997-11-13 1997-11-13 Metalloproteinase inhibitors

Publications (1)

Publication Number Publication Date
ES2195122T3 true ES2195122T3 (es) 2003-12-01

Family

ID=10807699

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97912351T Expired - Lifetime ES2195122T3 (es) 1997-11-13 1997-11-13 Inhibidores de metaloproteinasa.

Country Status (21)

Country Link
EP (1) EP1030842B1 (US06559137-20030506-C00039.png)
JP (1) JP2001523666A (US06559137-20030506-C00039.png)
KR (1) KR100485479B1 (US06559137-20030506-C00039.png)
AT (1) ATE236126T1 (US06559137-20030506-C00039.png)
AU (1) AU740420B2 (US06559137-20030506-C00039.png)
BR (1) BR9714934A (US06559137-20030506-C00039.png)
CA (1) CA2310593C (US06559137-20030506-C00039.png)
DE (1) DE69720554T2 (US06559137-20030506-C00039.png)
DK (1) DK1030842T3 (US06559137-20030506-C00039.png)
ES (1) ES2195122T3 (US06559137-20030506-C00039.png)
GB (1) GB2333524A (US06559137-20030506-C00039.png)
HU (1) HUP0002811A3 (US06559137-20030506-C00039.png)
IL (1) IL135210A0 (US06559137-20030506-C00039.png)
NO (1) NO315702B1 (US06559137-20030506-C00039.png)
NZ (1) NZ503642A (US06559137-20030506-C00039.png)
PL (1) PL189542B1 (US06559137-20030506-C00039.png)
PT (1) PT1030842E (US06559137-20030506-C00039.png)
RU (1) RU2198164C2 (US06559137-20030506-C00039.png)
TR (1) TR200001353T2 (US06559137-20030506-C00039.png)
TW (1) TW474919B (US06559137-20030506-C00039.png)
WO (1) WO1999025693A1 (US06559137-20030506-C00039.png)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20030701A1 (es) 2001-12-20 2003-08-21 Schering Corp Compuestos para el tratamiento de trastornos inflamatorios

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1049651C (zh) * 1994-01-20 2000-02-23 英国生物技术药物有限公司 金属蛋白酶抑制剂
WO1997003966A1 (en) * 1995-07-19 1997-02-06 British Biotech Pharmaceuticals Limited N-(amino acid) substituted succinic acid amide derivatives as metalloproteinase inhibitors

Also Published As

Publication number Publication date
NO315702B1 (no) 2003-10-13
GB2333524A (en) 1999-07-28
DK1030842T3 (da) 2003-07-28
BR9714934A (pt) 2000-10-03
EP1030842B1 (en) 2003-04-02
CA2310593C (en) 2007-05-08
AU4958497A (en) 1999-06-07
RU2198164C2 (ru) 2003-02-10
NZ503642A (en) 2001-10-26
HUP0002811A2 (hu) 2001-01-29
PT1030842E (pt) 2003-07-31
ATE236126T1 (de) 2003-04-15
IL135210A0 (en) 2001-05-20
EP1030842A1 (en) 2000-08-30
NO20002480L (no) 2000-05-12
DE69720554D1 (de) 2003-05-08
JP2001523666A (ja) 2001-11-27
CA2310593A1 (en) 1999-05-27
KR100485479B1 (ko) 2005-04-27
TW474919B (en) 2002-02-01
KR20010031879A (ko) 2001-04-16
TR200001353T2 (tr) 2000-10-23
AU740420B2 (en) 2001-11-01
HUP0002811A3 (en) 2002-11-28
PL340494A1 (en) 2001-02-12
DE69720554T2 (de) 2004-01-08
PL189542B1 (pl) 2005-08-31
WO1999025693A1 (en) 1999-05-27
GB9816317D0 (en) 1998-09-23
NO20002480D0 (no) 2000-05-12

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