ES2192141B1 - Formulaciones acrilicas de curado en frio con activadores derivados de diaminodifenilcarbinol de baja toxicidad. - Google Patents

Formulaciones acrilicas de curado en frio con activadores derivados de diaminodifenilcarbinol de baja toxicidad.

Info

Publication number
ES2192141B1
ES2192141B1 ES200200312A ES200200312A ES2192141B1 ES 2192141 B1 ES2192141 B1 ES 2192141B1 ES 200200312 A ES200200312 A ES 200200312A ES 200200312 A ES200200312 A ES 200200312A ES 2192141 B1 ES2192141 B1 ES 2192141B1
Authority
ES
Spain
Prior art keywords
cement
low toxicity
formulations
acrylic
cold curing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
ES200200312A
Other languages
English (en)
Other versions
ES2192141A1 (es
Inventor
Blanca Vazquez Lasa
Julio San Roman Del Barrio
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Consejo Superior de Investigaciones Cientificas CSIC
Original Assignee
Consejo Superior de Investigaciones Cientificas CSIC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Consejo Superior de Investigaciones Cientificas CSIC filed Critical Consejo Superior de Investigaciones Cientificas CSIC
Priority to ES200200312A priority Critical patent/ES2192141B1/es
Priority to AU2003208725A priority patent/AU2003208725A1/en
Priority to PCT/ES2003/000055 priority patent/WO2003066117A1/es
Publication of ES2192141A1 publication Critical patent/ES2192141A1/es
Application granted granted Critical
Publication of ES2192141B1 publication Critical patent/ES2192141B1/es
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/06—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • A61K6/083—
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00—Preparations for dentistry
    • A61K6/80—Preparations for artificial teeth, for filling teeth or for capping teeth
    • A61K6/884—Preparations for artificial teeth, for filling teeth or for capping teeth comprising natural or synthetic resins
    • A61K6/887—Compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

Landscapes

  • Health & Medical Sciences (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plastic & Reconstructive Surgery (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Surgery (AREA)
  • Materials For Medical Uses (AREA)

Abstract

Formulaciones acrílicas de curado en frío con activadores derivados de diaminodifenilcarbinol de baja toxicidad. La presente invención está relacionada con el desarrollo de formulaciones acrílicas de curado en frío para su uso como composiciones precursoras de cementos óseos de baja toxicidad y buena biocompatibilidad. Los cementos óseos poliméricos se vienen empleando durante las últimas décadas como soportes de liberación controlada de medicamentos y en cirugía ortopédica y traumatología para la fijación de prótesis de articulaciones siendo la función del cemento óseo la inmovilización de la prótesis. Sin embargo, se han descrito ciertas reacciones adversas producidas por el cemento a medio y largo plazo que se relacionan principalmente con la composición química del cemento y/o sus propiedades físicas.
ES200200312A 2002-02-08 2002-02-08 Formulaciones acrilicas de curado en frio con activadores derivados de diaminodifenilcarbinol de baja toxicidad. Expired - Fee Related ES2192141B1 (es)

Priority Applications (3)

Application Number Priority Date Filing Date Title
ES200200312A ES2192141B1 (es) 2002-02-08 2002-02-08 Formulaciones acrilicas de curado en frio con activadores derivados de diaminodifenilcarbinol de baja toxicidad.
AU2003208725A AU2003208725A1 (en) 2002-02-08 2003-01-31 Cold-curing acrylic formulations comprising low toxicity activators derived from diaminodiphenylcarbinol
PCT/ES2003/000055 WO2003066117A1 (es) 2002-02-08 2003-01-31 Formulaciones acrílicas de curado en frío con activadores derivados de diaminodifenilcarbinol de baja toxicidad

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES200200312A ES2192141B1 (es) 2002-02-08 2002-02-08 Formulaciones acrilicas de curado en frio con activadores derivados de diaminodifenilcarbinol de baja toxicidad.

Publications (2)

Publication Number Publication Date
ES2192141A1 ES2192141A1 (es) 2003-09-16
ES2192141B1 true ES2192141B1 (es) 2005-02-16

Family

ID=27675918

Family Applications (1)

Application Number Title Priority Date Filing Date
ES200200312A Expired - Fee Related ES2192141B1 (es) 2002-02-08 2002-02-08 Formulaciones acrilicas de curado en frio con activadores derivados de diaminodifenilcarbinol de baja toxicidad.

Country Status (3)

Country Link
AU (1) AU2003208725A1 (es)
ES (1) ES2192141B1 (es)
WO (1) WO2003066117A1 (es)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110339395A (zh) * 2018-04-03 2019-10-18 暨南大学 一种pmma基的水合骨水泥及其制备方法与应用

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10332680A1 (de) * 2003-07-18 2005-02-17 Biomet Deutschland Gmbh Verwendung von antiseptischen Wirkstoffen in PMMA-Knochenzementen
CN107041970B (zh) * 2016-12-20 2020-12-15 中山大学 一种高无机组分的复合型骨水泥及其制备方法和应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08245329A (ja) * 1995-03-13 1996-09-24 G C:Kk 義歯床用裏装材
GB9928837D0 (en) * 1999-12-06 2000-02-02 Abonetics Ltd Novel bone cement

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DEB, S. et al.: Water absortion characteristics and cytotoxic and biological evaluation of bone cements formulated with a novel activator. J. of Biomedical Materials Research, 1999, Vol. 48, nº 5, páginas 719-725, resumen, tabla I. *
RÉTHY, E. et al.: Sinthetische lineare polimere V. Die-wirkung der tetra alkyldiamino- diaryl-aktivatoren auf die polymerisation der monomer- polymer-mischungen des methyl methacrylates in anwesenheit von benzoylperoxyd. Macromol. Chem., 1958, Vol. 25, páginas 176-185. \\ Y 3-6,9,10 *
VÁZQUEZ, B. et al.: "Application of long chain amine activator in conventional acrylic bone cement". J. of Biomedical Materials Research, 1998, Vol. 43, nº 2, páginas 131-139, resumen, tabla I. *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110339395A (zh) * 2018-04-03 2019-10-18 暨南大学 一种pmma基的水合骨水泥及其制备方法与应用
CN110339395B (zh) * 2018-04-03 2021-09-21 暨南大学 一种pmma基的水合骨水泥及其制备方法与应用

Also Published As

Publication number Publication date
ES2192141A1 (es) 2003-09-16
AU2003208725A1 (en) 2003-09-02
WO2003066117A1 (es) 2003-08-14

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