ES2191022T3 - Utilizacion de derivados de la tetrahidropiridina para la preparacion de medicamentos cardioprotectores. - Google Patents

Utilizacion de derivados de la tetrahidropiridina para la preparacion de medicamentos cardioprotectores.

Info

Publication number
ES2191022T3
ES2191022T3 ES94400597T ES94400597T ES2191022T3 ES 2191022 T3 ES2191022 T3 ES 2191022T3 ES 94400597 T ES94400597 T ES 94400597T ES 94400597 T ES94400597 T ES 94400597T ES 2191022 T3 ES2191022 T3 ES 2191022T3
Authority
ES
Spain
Prior art keywords
preparation
cardioprotecting
tetrahydropiridine
medicines
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94400597T
Other languages
English (en)
Inventor
Allan Stewart Manning
Pierre Paul Chatelain
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Sanofi Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Synthelabo SA filed Critical Sanofi Synthelabo SA
Application granted granted Critical
Publication of ES2191022T3 publication Critical patent/ES2191022T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A LA UTILIZACION DE UNA 1-[2NAFTILETIL]-4-(3-TRIFLUOROMETILFENIL)-1,2,3,6-TETRAHIDROPIRIDINA DE FORMULA (I) O DE SUS SALES DE ADICION CON ACIDOS FARMACEUTICAMENTE ACEPTABLES, PARA LA PREPARACION DE MEDICAMENTOS CARDIOPROTECTORES.
ES94400597T 1993-03-18 1994-03-18 Utilizacion de derivados de la tetrahidropiridina para la preparacion de medicamentos cardioprotectores. Expired - Lifetime ES2191022T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9303149A FR2702656B1 (fr) 1993-03-18 1993-03-18 Utilisation de derives de la tetrahydropyridine pour la preparation de medicaments cardioprotecteurs.

Publications (1)

Publication Number Publication Date
ES2191022T3 true ES2191022T3 (es) 2003-09-01

Family

ID=9445120

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94400597T Expired - Lifetime ES2191022T3 (es) 1993-03-18 1994-03-18 Utilizacion de derivados de la tetrahidropiridina para la preparacion de medicamentos cardioprotectores.

Country Status (9)

Country Link
US (1) US5378709A (es)
EP (1) EP0615755B1 (es)
JP (1) JP2650847B2 (es)
AT (1) ATE230991T1 (es)
DE (1) DE69432000T2 (es)
DK (1) DK0615755T3 (es)
ES (1) ES2191022T3 (es)
FR (1) FR2702656B1 (es)
SG (1) SG48784A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5891465A (en) * 1996-05-14 1999-04-06 Biozone Laboratories, Inc. Delivery of biologically active material in a liposomal formulation for administration into the mouth
FR2772614B1 (fr) 1997-12-24 2000-03-10 Sanofi Sa Solution aqueuse a base de chlorhydrate de 1- [ 2-(2-naphtyl)ethyl]-4- (3-trifluoromethylphenyl) -1,2,3,6-tetrahydropyridine et composition pharmaceutique buvable en contenant
MXPA03003401A (es) * 2000-10-16 2004-06-30 Neopharm Inc Formulacion liposomica de mitoxantrona.
US20090076048A1 (en) * 2007-09-19 2009-03-19 Protia, Llc Deuterium-enriched xaliproden

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2639226B1 (fr) * 1988-11-18 1993-11-05 Sanofi Utilisation de trifluoromethylphenyltetrahydropyridines pour la preparation de medicaments destines a combattre les troubles anxio-depressifs
FR2650505B1 (fr) * 1989-08-07 1994-06-03 Midy Spa Utilisation de trifluoromethylphenyltetrahydropyridines pour la preparation de medicaments destines a combattre les troubles de la motricite intestinale
GB8919661D0 (en) * 1989-08-31 1989-10-11 Univ Alberta Superoxide dismutase-catalase conjugates
FR2662355B1 (fr) * 1990-05-22 1994-11-10 Sanofi Sa Utilisation de la 1-[2-(2-naphtyl)ethyl]-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine pour la preparation de medicaments destines au traitement de troubles cerebraux et neuronaux.
FR2672213B1 (fr) * 1991-02-05 1995-03-10 Sanofi Sa Utilisation de derives 4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridiniques comme capteurs de radicaux libres.

Also Published As

Publication number Publication date
DE69432000D1 (de) 2003-02-20
SG48784A1 (en) 1998-05-18
DK0615755T3 (da) 2003-03-17
US5378709A (en) 1995-01-03
EP0615755B1 (fr) 2003-01-15
JP2650847B2 (ja) 1997-09-10
FR2702656B1 (fr) 1995-06-16
EP0615755A1 (fr) 1994-09-21
ATE230991T1 (de) 2003-02-15
DE69432000T2 (de) 2003-09-04
FR2702656A1 (fr) 1994-09-23
JPH06340628A (ja) 1994-12-13

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