ES2190605T3 - Peptido con afinidad hacia el factor de coagulacion viii. - Google Patents
Peptido con afinidad hacia el factor de coagulacion viii.Info
- Publication number
- ES2190605T3 ES2190605T3 ES98946452T ES98946452T ES2190605T3 ES 2190605 T3 ES2190605 T3 ES 2190605T3 ES 98946452 T ES98946452 T ES 98946452T ES 98946452 T ES98946452 T ES 98946452T ES 2190605 T3 ES2190605 T3 ES 2190605T3
- Authority
- ES
- Spain
- Prior art keywords
- peptide
- affinity
- factor viii
- coagulation factor
- dodecapeptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
Abstract
Péptido con la estructura R1 ¿ X ¿ R3 en la cual son R1 = NH2 o un péptido, R2 = COOH o un péptido y X = al menos un tripéptido, en especial un hepta- hasta dodeca-péptido, que establece una unión por afinidad con Factor VIII.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19740310A DE19740310A1 (de) | 1997-09-13 | 1997-09-13 | Peptid mit Affinität zu Gerinnungsfaktor VIII |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2190605T3 true ES2190605T3 (es) | 2003-08-01 |
Family
ID=7842252
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES98946452T Expired - Lifetime ES2190605T3 (es) | 1997-09-13 | 1998-09-12 | Peptido con afinidad hacia el factor de coagulacion viii. |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP1012175B1 (es) |
CN (1) | CN1203088C (es) |
AT (1) | ATE230758T1 (es) |
BR (1) | BR9812435A (es) |
DE (2) | DE19740310A1 (es) |
DK (1) | DK1012175T3 (es) |
ES (1) | ES2190605T3 (es) |
HK (1) | HK1026436A1 (es) |
WO (1) | WO1999014232A1 (es) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AUPR638801A0 (en) * | 2001-07-13 | 2001-08-09 | Life Therapeutics Limited | Factor viii separation |
AU2011253661B2 (en) * | 2005-04-26 | 2013-06-13 | Boehringer Ingelheim Rcv Gmbh & Co Kg | Production of recombinant proteins by autoproteolytic cleavage of a fusion protein |
US8163890B2 (en) * | 2005-04-26 | 2012-04-24 | Sandoz Ag | Production of recombinant proteins by autoproteolytic cleavage of a fusion protein |
GB0508435D0 (en) * | 2005-04-26 | 2005-06-01 | Sandoz Ag | Organic compounds |
US20090215025A1 (en) | 2005-12-07 | 2009-08-27 | Technische Universitat Munchen | Small peptidic and peptido-mimetic affinity ligands for factor viii and factor viii-like proteins |
WO2010005293A1 (en) * | 2008-06-16 | 2010-01-14 | Chiralix B.V. | Peptidylarginine deiminase (pad) inhibitors |
CN101303356B (zh) * | 2008-06-20 | 2012-07-18 | 许贤豪 | 一种筛选适用于检测和纯化凝血第八因子的单克隆抗体的方法 |
CN103506080A (zh) * | 2012-06-19 | 2014-01-15 | 汪志友 | 一种用于分离纯化凝血因子viii的介质及其制备方法 |
CN106046148B (zh) * | 2016-06-27 | 2019-08-23 | 新乡医学院 | 一种利用肽配基亲和纯化凝血因子viii的方法 |
CN110448719B (zh) * | 2019-06-28 | 2020-05-22 | 浙江大学 | 一种促进凝血的丝素-多肽电纺膜及其制备方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1988007507A1 (en) * | 1987-04-03 | 1988-10-06 | Hermann Hofmann | Process for composting organic material and device for carrying out this process |
US5043429B1 (en) * | 1987-05-01 | 1997-10-14 | Scripps Research Inst | Protein fragments containing factor VIII binding domain of von willebrand factor |
US5200510A (en) * | 1987-06-16 | 1993-04-06 | Zymogenetics, Inc. | Method for purifying factor viii:c, von willebrand factor and complexes thereof |
DE19521313A1 (de) * | 1995-06-12 | 1996-12-19 | Max Planck Inst Fuer Physiolog | Verfahren zur affinitätschromatographischen Aufreinigung von Faktor VIII |
FR2748028B1 (fr) * | 1996-04-30 | 1998-08-14 | Lab Francais Du Fractionnement | Peptides derives du facteur von willebrand et leur utilisation comme anticoagulant |
-
1997
- 1997-09-13 DE DE19740310A patent/DE19740310A1/de not_active Withdrawn
-
1998
- 1998-09-12 DK DK98946452T patent/DK1012175T3/da active
- 1998-09-12 DE DE59806878T patent/DE59806878D1/de not_active Revoked
- 1998-09-12 AT AT98946452T patent/ATE230758T1/de not_active IP Right Cessation
- 1998-09-12 BR BR9812435-8A patent/BR9812435A/pt not_active IP Right Cessation
- 1998-09-12 EP EP98946452A patent/EP1012175B1/de not_active Revoked
- 1998-09-12 CN CNB98811089XA patent/CN1203088C/zh not_active Expired - Fee Related
- 1998-09-12 WO PCT/EP1998/005822 patent/WO1999014232A1/de not_active Application Discontinuation
- 1998-09-12 ES ES98946452T patent/ES2190605T3/es not_active Expired - Lifetime
-
2000
- 2000-09-12 HK HK00105761A patent/HK1026436A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DK1012175T3 (da) | 2003-04-28 |
DE19740310A1 (de) | 1999-04-01 |
CN1278829A (zh) | 2001-01-03 |
CN1203088C (zh) | 2005-05-25 |
WO1999014232A1 (de) | 1999-03-25 |
ATE230758T1 (de) | 2003-01-15 |
BR9812435A (pt) | 2000-09-26 |
HK1026436A1 (en) | 2000-12-15 |
EP1012175B1 (de) | 2003-01-08 |
EP1012175A1 (de) | 2000-06-28 |
DE59806878D1 (de) | 2003-02-13 |
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