ES2188336B1 - Aductos de albumina soluble con complejos polihidroxilados (polialcoholicos) de hierro trivalente, metodo de obtencion y preparaciones farmaceuticas y dieteticas que los contienen. - Google Patents

Aductos de albumina soluble con complejos polihidroxilados (polialcoholicos) de hierro trivalente, metodo de obtencion y preparaciones farmaceuticas y dieteticas que los contienen.

Info

Publication number
ES2188336B1
ES2188336B1 ES200002496A ES200002496A ES2188336B1 ES 2188336 B1 ES2188336 B1 ES 2188336B1 ES 200002496 A ES200002496 A ES 200002496A ES 200002496 A ES200002496 A ES 200002496A ES 2188336 B1 ES2188336 B1 ES 2188336B1
Authority
ES
Spain
Prior art keywords
soluble
polyhydroxylated
complexes
trivalent iron
pharmaceutical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
ES200002496A
Other languages
English (en)
Other versions
ES2188336A1 (es
Inventor
Fernando Fussi
Victor Diaz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tedec Meiji Farma SA
Syntex Uruguaya SA
Original Assignee
Tedec Meiji Farma SA
Syntex Uruguaya SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tedec Meiji Farma SA, Syntex Uruguaya SA filed Critical Tedec Meiji Farma SA
Priority to ES200002496A priority Critical patent/ES2188336B1/es
Priority to KR1020010012607A priority patent/KR20020033020A/ko
Publication of ES2188336A1 publication Critical patent/ES2188336A1/es
Application granted granted Critical
Publication of ES2188336B1 publication Critical patent/ES2188336B1/es
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/38—Albumins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Aductos de albúmina soluble con complejos polihidroxilados (polialcohólicos) de hierro trivalente, método de obtención y preparaciones farmacéuticas y dietéticas. El aducto, soluble en agua, comprende un complejo polihidroxilado de hierro trivalente con albúmina soluble y desensibilizada. El compuesto polihidroxilado comprende un compuesto que contiene más de un grupo hidróxido y que es capaz de formar complejos con hierro trivalente. La albúmina ha sido sometida a un tratamiento térmico, alcalino y oxidante para su solubilización sin afectar a su peso molecular. El aducto se obtiene mezclando la solución del complejo férrico con la solución de albúmina tratada. Estos aductos son adecuados para la administración oral de complejos férricos, por lo que son adecuados para el tratamiento de estados carenciales de hierro y/o para el aporte de dicho elemento.
ES200002496A 2000-10-18 2000-10-18 Aductos de albumina soluble con complejos polihidroxilados (polialcoholicos) de hierro trivalente, metodo de obtencion y preparaciones farmaceuticas y dieteticas que los contienen. Expired - Fee Related ES2188336B1 (es)

Priority Applications (2)

Application Number Priority Date Filing Date Title
ES200002496A ES2188336B1 (es) 2000-10-18 2000-10-18 Aductos de albumina soluble con complejos polihidroxilados (polialcoholicos) de hierro trivalente, metodo de obtencion y preparaciones farmaceuticas y dieteticas que los contienen.
KR1020010012607A KR20020033020A (ko) 2000-10-18 2001-03-12 3가철의 폴리히드록실화 착체(폴리알코올)를 가진 가용성알부민의 첨가생성물, 그 취득방법, 그 첨가생성물을포함한 의약조성물 및 식이요법 조성물

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES200002496A ES2188336B1 (es) 2000-10-18 2000-10-18 Aductos de albumina soluble con complejos polihidroxilados (polialcoholicos) de hierro trivalente, metodo de obtencion y preparaciones farmaceuticas y dieteticas que los contienen.

Publications (2)

Publication Number Publication Date
ES2188336A1 ES2188336A1 (es) 2003-06-16
ES2188336B1 true ES2188336B1 (es) 2004-04-01

Family

ID=8495290

Family Applications (1)

Application Number Title Priority Date Filing Date
ES200002496A Expired - Fee Related ES2188336B1 (es) 2000-10-18 2000-10-18 Aductos de albumina soluble con complejos polihidroxilados (polialcoholicos) de hierro trivalente, metodo de obtencion y preparaciones farmaceuticas y dieteticas que los contienen.

Country Status (2)

Country Link
KR (1) KR20020033020A (es)
ES (1) ES2188336B1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2258391B1 (es) * 2004-11-03 2007-12-01 Tedec-Meiji Farma, S.A. Aducto de ovoalbumina soluble con complejos polialcoholicos de hierro trivalente y metodo para su obtencion.
CN114365792A (zh) 2014-11-11 2022-04-19 克莱拉食品公司 用于生成卵清蛋白的方法和组合物
KR20220034848A (ko) 2019-07-11 2022-03-18 클라라 푸드즈 컴퍼니 단백질 조성물 및 이의 섭취 가능한 제품
US10927360B1 (en) 2019-08-07 2021-02-23 Clara Foods Co. Compositions comprising digestive enzymes

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2123432B1 (es) * 1996-10-15 1999-10-01 Syntex Sa Aductos de complejos polihidroxilados de hierro trivalente con albumina soluble, metodo de obtencion y preparaciones farmaceuticas y dieteticas que los contienen.

Also Published As

Publication number Publication date
KR20020033020A (ko) 2002-05-04
ES2188336A1 (es) 2003-06-16

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