ES2185669T3 - Mutantes supresores de las bacterias de acido lactico y su utilizacion como marcadores selectivos y como medios de contencion en las bacterias de acido lactico. - Google Patents

Mutantes supresores de las bacterias de acido lactico y su utilizacion como marcadores selectivos y como medios de contencion en las bacterias de acido lactico.

Info

Publication number
ES2185669T3
ES2185669T3 ES94929490T ES94929490T ES2185669T3 ES 2185669 T3 ES2185669 T3 ES 2185669T3 ES 94929490 T ES94929490 T ES 94929490T ES 94929490 T ES94929490 T ES 94929490T ES 2185669 T3 ES2185669 T3 ES 2185669T3
Authority
ES
Spain
Prior art keywords
lactic acid
acid bacteria
mutants
suppressors
containment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94929490T
Other languages
English (en)
Inventor
Francoise Dickely
Eric Johansen
Dan Nilsson
Egon Bech Hansen
Per Stroeman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chr Hansen AS
Original Assignee
Chr Hansen AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chr Hansen AS filed Critical Chr Hansen AS
Application granted granted Critical
Publication of ES2185669T3 publication Critical patent/ES2185669T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C12N15/68—Stabilisation of the vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/746—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for lactic acid bacteria (Streptococcus; Lactococcus; Lactobacillus; Pediococcus; Enterococcus; Leuconostoc; Propionibacterium; Bifidobacterium; Sporolactobacillus)

Landscapes

  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

SE PRESENTA MUTANTES DE BACTERIAS DEL ACIDO LACTICO O DE PLASMIDOS CAPACES DE REPLICARSE EN BACTERIAS DE ACIDO LACTICO, QUE COMPRENDEN GENES QUE CODIFICAN EL SUPRESOR DE LA MUTACION SIN SENTIDO, EL USO DE TALES GENES SUPRESORES PARA CONFINAR UNA REPLICACION A UNA BACTERIA ESPECIFICA DEL ACIDO LACTICO O A UNA BACTERIA DEL ACIDO LACTICO QUE CRECE EN UN MEDIO AMBIENTE PARTICULAR Y PARA CONTROLAR EL NUMERO DE CELULAS BACTERIANAS DEL ACIDO LACTICO EN UN MEDIO AMBIENTE EN PARTICULAR.
ES94929490T 1993-10-08 1994-10-07 Mutantes supresores de las bacterias de acido lactico y su utilizacion como marcadores selectivos y como medios de contencion en las bacterias de acido lactico. Expired - Lifetime ES2185669T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13339093A 1993-10-08 1993-10-08
US08/242,098 US5691185A (en) 1993-10-08 1994-05-13 Lactic acid bacterial suppressor mutants and their use as selective markers and as means of containment in lactic acid bacteria

Publications (1)

Publication Number Publication Date
ES2185669T3 true ES2185669T3 (es) 2003-05-01

Family

ID=26831333

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94929490T Expired - Lifetime ES2185669T3 (es) 1993-10-08 1994-10-07 Mutantes supresores de las bacterias de acido lactico y su utilizacion como marcadores selectivos y como medios de contencion en las bacterias de acido lactico.

Country Status (10)

Country Link
US (2) US5691185A (es)
EP (1) EP0722503B1 (es)
AT (1) ATE227774T1 (es)
AU (1) AU684556B2 (es)
CA (1) CA2160166C (es)
DE (1) DE69431727T2 (es)
DK (1) DK0722503T3 (es)
ES (1) ES2185669T3 (es)
NZ (1) NZ274481A (es)
WO (1) WO1995010621A1 (es)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7358083B1 (en) 1998-04-21 2008-04-15 Chr. Hansen A/S Food-grade cloning vector and their use in lactic acid bacteria
WO1999054488A1 (en) * 1998-04-21 1999-10-28 Chr. Hansen A/S Food-grade cloning vector and their use in lactic acid bacteria
FR2778921B1 (fr) * 1998-05-22 2001-05-11 Gervais Danone Sa Souches mutantes de lactobacillus bulgaricus depourvues d'activite beta-galactosidase
WO2000001799A2 (en) 1998-07-03 2000-01-13 Chr. Hansen A/S Method of preventing bacteriophage infection of bacterial cultures
US7892585B1 (en) * 1998-07-03 2011-02-22 Chr Hansen A/S Method of preventing bacteriophage infection of bacterial cultures
US6787348B1 (en) * 1998-08-26 2004-09-07 Chr. Hansen Liquid starter cultures having improved storage stability and use thereof
IL130303A0 (en) 1999-06-03 2000-06-01 M G Novobiotech Ltd A bacterial strain processed plant extracts and probiotic compositions for human and veterinary use
US7780961B2 (en) 2001-05-03 2010-08-24 Actogenix N.V. Self-containing Lactococcus strain
US7101565B2 (en) 2002-02-05 2006-09-05 Corpak Medsystems, Inc. Probiotic/prebiotic composition and delivery method
AU2003250250B2 (en) 2002-06-19 2008-02-14 Intrexon Actobiotics Nv Methods and means to promote gut absorption
WO2005052151A1 (en) * 2003-11-19 2005-06-09 Dow Global Technologies Inc. Improved protein expression systems
JP5410759B2 (ja) 2005-11-29 2014-02-05 アクトジェニックス・エヌブイ 抗原に対する粘膜寛容の誘導
EP1869983A1 (en) * 2006-06-23 2007-12-26 Chr. Hansen A/S Low post-acidifying lactic acid bacteria
EP2125010B1 (en) 2007-01-25 2014-06-04 Actogenix N.V. Treatment of immune disease by mucosal delivery of antigens using genetically modified lactobacillus
AU2010247938B2 (en) 2009-05-11 2016-02-18 Pelican Technology Holdings, Inc. Production of recombinant proteins utilizing non-antibiotic selection methods and the incorporation of non-natural amino acids therein
ES2778727T3 (es) 2014-08-25 2020-08-11 Geneweave Biosciences Inc Partículas de transducción no replicativas y sistemas indicadores basados en partículas de transducción
US11008602B2 (en) 2017-12-20 2021-05-18 Roche Molecular Systems, Inc. Non-replicative transduction particles and transduction particle-based reporter systems
DE18305781T1 (de) 2018-06-20 2020-09-17 Eligo Bioscience Bakterielles freisetzungsvehikel, verfahren zur herstellung und verwendungen davon
US11746352B2 (en) 2019-12-30 2023-09-05 Eligo Bioscience Microbiome modulation of a host by delivery of DNA payloads with minimized spread
US12098372B2 (en) 2019-12-30 2024-09-24 Eligo Bioscience Microbiome modulation of a host by delivery of DNA payloads with minimized spread
WO2022144381A1 (en) 2020-12-30 2022-07-07 Eligo Bioscience Microbiome modulation of a host by delivery of dna payloads with minimized spread
JP2024520940A (ja) 2021-05-12 2024-05-27 エリゴ・バイオサイエンス 産生細菌細胞及び産生方法におけるその使用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4687737A (en) * 1982-11-12 1987-08-18 Massachusetts Institute Of Technology Mammalian suppressor genes
JPS6486875A (en) * 1987-09-29 1989-03-31 Hoechst Japan Plasmid vector containing streptomycin-sensitive gene
NL8801529A (nl) * 1988-06-15 1990-01-02 Nl Zuivelonderzoek Inst Werkwijze voor het selecteren en stabiel handhaven van recombinant dna in melkzuurbacterien.

Also Published As

Publication number Publication date
DE69431727D1 (de) 2002-12-19
AU684556B2 (en) 1997-12-18
ATE227774T1 (de) 2002-11-15
WO1995010621A1 (en) 1995-04-20
EP0722503A1 (en) 1996-07-24
US5691185A (en) 1997-11-25
AU7852994A (en) 1995-05-04
CA2160166A1 (en) 1995-04-20
DE69431727T2 (de) 2003-08-14
NZ274481A (en) 1996-12-20
DK0722503T3 (da) 2003-02-24
EP0722503B1 (en) 2002-11-13
CA2160166C (en) 2003-05-20
US5866385A (en) 1999-02-02

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