ES2182042T3 - Procedimiento de preparacion de un preparado farmaceutico multiparticular de liberacion controlada plurisecuencial. - Google Patents
Procedimiento de preparacion de un preparado farmaceutico multiparticular de liberacion controlada plurisecuencial.Info
- Publication number
- ES2182042T3 ES2182042T3 ES97911313T ES97911313T ES2182042T3 ES 2182042 T3 ES2182042 T3 ES 2182042T3 ES 97911313 T ES97911313 T ES 97911313T ES 97911313 T ES97911313 T ES 97911313T ES 2182042 T3 ES2182042 T3 ES 2182042T3
- Authority
- ES
- Spain
- Prior art keywords
- pharmaceutical form
- procedure
- preparation
- prepared
- multiparticular
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
- Y10T428/2991—Coated
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
LA INVENCION SE REFIERE A UN PROCEDIMIENTO DE PREPARACION DE UNA FORMA FARMACEUTICA MULTIPARTICULAR CON LIBERACION CONTROLADA PLURISECUENCIAL DEL TIPO DE LAS QUE PERMITEN GARANTIZAR EN EL ORGANISMO DEL PACIENTE UNA CONCENTRACION SUFICIENTE DE UNO O VARIOS PRINCIPIOS ACTIVOS POR UNA O DOS ADMINISTRACIONES EN 24 HORAS. DICHO PROCEDIMIENTO SE CARACTERIZA PORQUE LA FORMA FARMACEUTICA DEL TIPO EN CUESTION, QUE COMPRENDE AL MENOS DOS POBLACIONES DE PARTICULAS DISTINTAS POR SU REVESTIMIENTO, SE PREPARA, PREFERENTEMENTE DE MODO CONTINUO, EN EL INTERIOR DE UNA SOLA INSTALACION DE REVESTIMIENTO A PARTIR DE VARIOS ESFEROIDES MEDICAMENTOSOS SIMILARES Y DE UNO O VARIOS PRODUCTOS DE REVESTIMIENTO, ESTANDO LOS ESFEROIDES MEDICAMENTOSOS DIVIDIDOS EN TANTAS FRACCIONES COMO POBLACIONES DEBEN HABER EN LA FORMA FARMACEUTICA QUE HAY QUE PREPARAR, SIENDO LAS FRACCIONES DE ESFEROIDES MEDICAMENTOSOS ASI OBTENIDAS INTRODUCIDAS SUCESIVAMENTE EN LA UNICA INSTALACION DE REVESTIMIENTO PARA SER SOMETIDAS, SALVO OPCIONALMENTE LA ULTIMA, A UN TRATAMIENTO DE REVESTIMIENTO MEDIANTE TANTAS FRACCIONES DE UNO O DEL OTRO DE DICHOS PRODUCTOS DE REVESTIMIENTO, EFECTUANDOSE EL REVESTIMIENTO DE UNA FRACCION DADA DE ESFEROIDES MEDICAMENTOSOS EN PRESENCIA DE LOS ESFEROIDES MEDICAMENTOSOS DE LA O DE LAS FRACCIONES ANTERIORES QUE YA HAN SIDO SOMETIDAS A UN TRATAMIENTO DE REVESTIMIENTO. LOS ESFEROIDES MEDICAMENTOSOS ASI TRATADOS CONSTITUYEN UN CONJUNTO QUE SE CONFORMA A CONTINUACION PARA CONSTITUIR LA FORMA FARMACEUTICA BUSCADA.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9612818A FR2754710B1 (fr) | 1996-10-22 | 1996-10-22 | Procede de preparation d'une forme pharmaceutique multiparticulaire a liberation controlee plurisequentielle |
US08/757,060 US5958460A (en) | 1996-10-22 | 1996-11-26 | Preparation process for a multiparticulate pharmaceutical form with plurality of sequences of controlled release |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2182042T3 true ES2182042T3 (es) | 2003-03-01 |
Family
ID=26233058
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES97911313T Expired - Lifetime ES2182042T3 (es) | 1996-10-22 | 1997-10-21 | Procedimiento de preparacion de un preparado farmaceutico multiparticular de liberacion controlada plurisecuencial. |
Country Status (9)
Country | Link |
---|---|
US (1) | US5958460A (es) |
EP (1) | EP0949912B1 (es) |
JP (1) | JP4160122B2 (es) |
AU (1) | AU4873497A (es) |
DE (1) | DE69715667T2 (es) |
ES (1) | ES2182042T3 (es) |
FR (1) | FR2754710B1 (es) |
HK (1) | HK1023072A1 (es) |
WO (1) | WO1998017261A1 (es) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2778848B1 (fr) * | 1998-05-20 | 2001-11-23 | Prographarm Lab | Forme pharmaceutique multiparticulaire a liberation programmee et pulsee et son procede de preparation |
PT1126826E (pt) * | 1998-11-02 | 2008-11-25 | Elan Pharma Int Ltd | Composição de metilfenidato de libertação modificada multiparticulada |
US6039979A (en) * | 1999-01-13 | 2000-03-21 | Laboratoires Prographarm | Multiparticulate pharmaceutical form with programmed and pulsed release and process for its preparation |
ATE367153T1 (de) * | 1999-05-20 | 2007-08-15 | Elan Corp Plc | Multipartikuläre arzneizusammensetzungen mit gesteuerter wirkstoffabgabe enthaltend selektive inhibitoren der serotoninwiederaufnahme |
US10179130B2 (en) | 1999-10-29 | 2019-01-15 | Purdue Pharma L.P. | Controlled release hydrocodone formulations |
EP1623703B1 (en) | 1999-10-29 | 2011-10-05 | Euro-Celtique S.A. | Controlled release hydrocodone formulations |
HU230686B1 (en) | 2000-10-30 | 2017-08-28 | Euro Celtique Sa | Controlled release hydrocodone compositions |
ATE346590T1 (de) * | 2001-07-26 | 2006-12-15 | Ethypharm Sa | Umgehüllte allylamine oder benzylamine enthaltende granulate, verfahren zur herstellung und in der mundhöhle dispergierbare tabletten enthaltend die umgehüllten granulate |
FR2861990B1 (fr) * | 2003-11-10 | 2006-02-10 | Nouveaux Produits Pharma | Comprimes faiblement doses a reseau de polymeres |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4917899A (en) * | 1983-12-22 | 1990-04-17 | Elan Corporation Plc | Controlled absorption diltiazem formulation |
DK154963C (da) * | 1986-07-08 | 1989-06-26 | Danochemo As | Fremgangsmaade til fremstilling af pulverformet, fritflydende tocoferylsuccinat |
DK173505B1 (da) * | 1987-02-20 | 2001-01-15 | Pharmatec Internat S R L | Fremgangsmåde til fremstilling af en diltiazempellet med langsom afgivelse og anvendelse af således fremstillede pelleter t |
FR2623714B1 (fr) * | 1987-11-26 | 1990-04-20 | Ethypharm Sa | Forme a liberation prolongee du diltiazem, et son medicament ainsi obtenu |
ZA923474B (en) * | 1991-05-20 | 1993-01-27 | Marion Merrell Dow Inc | Diltiazem formulation |
-
1996
- 1996-10-22 FR FR9612818A patent/FR2754710B1/fr not_active Expired - Lifetime
- 1996-11-26 US US08/757,060 patent/US5958460A/en not_active Expired - Lifetime
-
1997
- 1997-10-21 AU AU48734/97A patent/AU4873497A/en not_active Abandoned
- 1997-10-21 JP JP51904798A patent/JP4160122B2/ja not_active Expired - Fee Related
- 1997-10-21 ES ES97911313T patent/ES2182042T3/es not_active Expired - Lifetime
- 1997-10-21 DE DE69715667T patent/DE69715667T2/de not_active Expired - Lifetime
- 1997-10-21 EP EP97911313A patent/EP0949912B1/fr not_active Expired - Lifetime
- 1997-10-21 WO PCT/FR1997/001889 patent/WO1998017261A1/fr active IP Right Grant
-
2000
- 2000-04-19 HK HK00102373A patent/HK1023072A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
FR2754710B1 (fr) | 1998-12-31 |
FR2754710A1 (fr) | 1998-04-24 |
JP4160122B2 (ja) | 2008-10-01 |
JP2001503398A (ja) | 2001-03-13 |
EP0949912A1 (fr) | 1999-10-20 |
EP0949912B1 (fr) | 2002-09-18 |
US5958460A (en) | 1999-09-28 |
WO1998017261A1 (fr) | 1998-04-30 |
AU4873497A (en) | 1998-05-15 |
HK1023072A1 (en) | 2000-09-01 |
DE69715667T2 (de) | 2003-05-22 |
DE69715667D1 (de) | 2002-10-24 |
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