ES2181315T3 - Membranas estratificadas para controlar el regimen de administracion para su utilizacion en dispositivos de electrotransporte. - Google Patents

Membranas estratificadas para controlar el regimen de administracion para su utilizacion en dispositivos de electrotransporte.

Info

Publication number
ES2181315T3
ES2181315T3 ES98963197T ES98963197T ES2181315T3 ES 2181315 T3 ES2181315 T3 ES 2181315T3 ES 98963197 T ES98963197 T ES 98963197T ES 98963197 T ES98963197 T ES 98963197T ES 2181315 T3 ES2181315 T3 ES 2181315T3
Authority
ES
Spain
Prior art keywords
distribution
pore size
membrane
porosity
electrode assembly
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES98963197T
Other languages
English (en)
Inventor
J Richard Gyory
Ronald P Haak
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alza Corp
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Application granted granted Critical
Publication of ES2181315T3 publication Critical patent/ES2181315T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0444—Membrane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0448—Drug reservoir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432—Anode and cathode
    • A61N1/0436—Material of the electrode

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Electrotherapy Devices (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Liquid Crystal (AREA)
  • Non-Mechanical Conveyors (AREA)
  • Medicinal Preparation (AREA)
  • Spinning Methods And Devices For Manufacturing Artificial Fibers (AREA)

Abstract

Dispositivo de electrotransporte (10) para la administración de un agente terapéutico a través de una superficie corporal, que comprende: un conjunto de contraelectrodo; por lo menos un conjunto de electrodo donador que comprende un electrodo (12), un depósito donador (16) que contiene el agente terapéutico y un conjunto de membrana (60) dispuesto entre el depósito donador (16) y la superficie corporal (100); caracterizado porque el dispositivo comprende además una fuente de energía eléctrica (24); un controlador para regular la distribución de energía procedente de dicha fuente de energía eléctrica (24) a dicho conjunto de contraelectrodo y dicho por lo menos un conjunto de electrodo donador; en el que dicho conjunto de membrana (60) comprende: una primera membrana (64) que presenta un primer tamaño medio de poros, una primera porosidad, una primera distribución de tamaños de poros y una primera distribución espacial de poros, estando adherida dicha primera membrana a una segunda membrana (62) que presenta un segundo tamaño medio de poros, una segunda porosidad, una segunda distribución de tamaños de poros y una segunda distribución espacial de poros, en el que dicha primera porosidad es inferior a la segunda porosidad, y en el que el primer tamaño medio de poros, la primera distribución de tamaños de poros, y la primera distribución espacial de poros son sustancialmente iguales al segundo tamaño medio de poros, la segunda distribución de tamaños de poros y la segunda distribución de poros.
ES98963197T 1997-12-18 1998-12-14 Membranas estratificadas para controlar el regimen de administracion para su utilizacion en dispositivos de electrotransporte. Expired - Lifetime ES2181315T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US6804797P 1997-12-18 1997-12-18

Publications (1)

Publication Number Publication Date
ES2181315T3 true ES2181315T3 (es) 2003-02-16

Family

ID=22080088

Family Applications (1)

Application Number Title Priority Date Filing Date
ES98963197T Expired - Lifetime ES2181315T3 (es) 1997-12-18 1998-12-14 Membranas estratificadas para controlar el regimen de administracion para su utilizacion en dispositivos de electrotransporte.

Country Status (11)

Country Link
US (1) US6163720A (es)
EP (1) EP1039949B1 (es)
JP (2) JP4038019B2 (es)
KR (1) KR100584630B1 (es)
CN (1) CN1282262A (es)
AT (1) ATE223244T1 (es)
AU (1) AU1827599A (es)
CA (1) CA2315228C (es)
DE (1) DE69807746T2 (es)
ES (1) ES2181315T3 (es)
WO (1) WO1999030774A1 (es)

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ATE479466T1 (de) * 2001-12-19 2010-09-15 Alza Corp Behältergehäuse mit darin integriertem leitfähigem bereich
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US20070021735A1 (en) * 2005-07-15 2007-01-25 Sai Bhavaraju Dual membrane electro-osmotic fluid delivery device
US8386030B2 (en) 2005-08-08 2013-02-26 Tti Ellebeau, Inc. Iontophoresis device
US20100016781A1 (en) * 2005-08-29 2010-01-21 Mizuo Nakayama Iontophoresis device selecting drug to be administered on the basis of information form sensor
JP4804904B2 (ja) * 2005-12-09 2011-11-02 Ｔｔｉ・エルビュー株式会社 イオントフォレーシス装置包装品
US20080004671A1 (en) * 2006-06-28 2008-01-03 Alza Corporation Vagus nerve stimulation via orally delivered apparatus
US20080009782A1 (en) * 2006-06-28 2008-01-10 Alza Corporation Methods and Devices for Transdermal Electrotransport Delivery of Lofentanil and Carfentanil
US8062783B2 (en) * 2006-12-01 2011-11-22 Tti Ellebeau, Inc. Systems, devices, and methods for powering and/or controlling devices, for instance transdermal delivery devices
US8197844B2 (en) 2007-06-08 2012-06-12 Activatek, Inc. Active electrode for transdermal medicament administration
CA2688184A1 (en) 2007-06-08 2008-12-18 Dexcom, Inc. Integrated medicament delivery device for use with continuous analyte sensor
EP4159114B1 (en) 2007-10-09 2024-04-10 DexCom, Inc. Integrated insulin delivery system with continuous glucose sensor
US8862223B2 (en) 2008-01-18 2014-10-14 Activatek, Inc. Active transdermal medicament patch and circuit board for same
KR101286272B1 (ko) * 2011-07-20 2013-07-15 (재)예수병원유지재단 피복재 및 전기자극기가 구비된 의료기기
AU2014290745A1 (en) 2013-07-19 2015-12-17 Dexcom, Inc. Time averaged basal rate optimizer
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Also Published As

Publication number Publication date
US6163720A (en) 2000-12-19
KR100584630B1 (ko) 2006-05-30
CN1282262A (zh) 2001-01-31
CA2315228A1 (en) 1999-06-24
EP1039949B1 (en) 2002-09-04
DE69807746D1 (de) 2002-10-10
ATE223244T1 (de) 2002-09-15
JP4139844B2 (ja) 2008-08-27
DE69807746T2 (de) 2003-01-02
AU1827599A (en) 1999-07-05
JP2007283118A (ja) 2007-11-01
JP2002508229A (ja) 2002-03-19
KR20010024727A (ko) 2001-03-26
WO1999030774A1 (en) 1999-06-24
CA2315228C (en) 2007-09-18
EP1039949A1 (en) 2000-10-04
JP4038019B2 (ja) 2008-01-23

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