ES2179853T3 - Compuestos de biotina-silanos y matriz de fijacion que contiene estos compuestos. - Google Patents
Compuestos de biotina-silanos y matriz de fijacion que contiene estos compuestos.Info
- Publication number
- ES2179853T3 ES2179853T3 ES95100632T ES95100632T ES2179853T3 ES 2179853 T3 ES2179853 T3 ES 2179853T3 ES 95100632 T ES95100632 T ES 95100632T ES 95100632 T ES95100632 T ES 95100632T ES 2179853 T3 ES2179853 T3 ES 2179853T3
- Authority
- ES
- Spain
- Prior art keywords
- spr
- gps
- iii
- binding
- aoao
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000011159 matrix material Substances 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 title 2
- 238000009739 binding Methods 0.000 abstract 5
- 230000027455 binding Effects 0.000 abstract 4
- 239000012876 carrier material Substances 0.000 abstract 4
- BLRPTPMANUNPDV-UHFFFAOYSA-N Silane Chemical compound [SiH4] BLRPTPMANUNPDV-UHFFFAOYSA-N 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 229910000077 silane Inorganic materials 0.000 abstract 2
- 125000006850 spacer group Chemical group 0.000 abstract 2
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 239000012491 analyte Substances 0.000 abstract 1
- 239000011230 binding agent Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 239000000376 reactant Substances 0.000 abstract 1
- 239000007790 solid phase Substances 0.000 abstract 1
- 230000009870 specific binding Effects 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/34—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
- A61L33/0076—Chemical modification of the substrate
- A61L33/0082—Chemical modification of the substrate by reacting with an organic compound other than heparin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54353—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Public Health (AREA)
- Pathology (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Food Science & Technology (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Surgery (AREA)
- Dermatology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Abstract
LA INVENCION SE REFIERE A UNA MATRIZ DE AGLOMERANTE, CONTENIENDO UN MATERIAL PORTADOR CON UNA SUPERFICIE OXIDICA Y UN REACTIVO DE FASE SOLIDA LIGADO DE FORMA COVALENTE A TRAVES DE GRUPO DE ANCLAJE, QUE DISPONE DE CAPACIDAD DE AGLOMERACION CON AL MENOS UN PARTNER DE REACCION LIBRE, CARACTERIZANDOSE PORQUE EL REACTIVO DE FASE SOLIDA FORMA UNA CAPA DE AGLOMERANTE DILUIDA Y DE FORMA LATERAL ESENCIALMENTE HOMOGENEA EN LA SUPERFICIE DEL MATERIAL PORTADOR, DE MODO QUE LOS GRUPOS DE ANCLAJE SON GRUPOS SILANO Y SE UNEN CON EL REACTIVO DE FASE SOLIDA A TRAVES DE UNA MOLECULA ESPACIADORA.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4401450 | 1994-01-19 | ||
DE4435728A DE4435728A1 (de) | 1994-01-19 | 1994-10-06 | Biotinsilan-Verbindungen und diese Verbindungen enthaltende Bindematrix |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2179853T3 true ES2179853T3 (es) | 2003-02-01 |
Family
ID=25933130
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES95100632T Expired - Lifetime ES2179853T3 (es) | 1994-01-19 | 1995-01-18 | Compuestos de biotina-silanos y matriz de fijacion que contiene estos compuestos. |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP0664452B1 (es) |
JP (1) | JP3214795B2 (es) |
AT (1) | ATE221660T1 (es) |
ES (1) | ES2179853T3 (es) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6472148B1 (en) | 1994-09-26 | 2002-10-29 | President And Fellows Of Harvard College | Molecular recognition at surfaces derivatized with self-assembled monolayers |
US5620850A (en) | 1994-09-26 | 1997-04-15 | President And Fellows Of Harvard College | Molecular recognition at surfaces derivatized with self-assembled monolayers |
US7045285B1 (en) | 1996-11-05 | 2006-05-16 | Clinical Micro Sensors, Inc. | Electronic transfer moieties attached to peptide nucleic acids |
DE19715484A1 (de) | 1997-04-14 | 1998-10-15 | Boehringer Mannheim Gmbh | Verfahren zum Aufbringen von Reagenzspots |
DE19748489A1 (de) | 1997-11-03 | 1999-05-06 | Roche Diagnostics Gmbh | Polyethylenglykol-derivatisierte Biomoleküle und deren Verwendung in heterogenen Nachweisverfahren |
AU2583899A (en) | 1998-02-04 | 1999-08-23 | Invitrogen Corporation | Microarrays and uses therefor |
US6406921B1 (en) * | 1998-07-14 | 2002-06-18 | Zyomyx, Incorporated | Protein arrays for high-throughput screening |
US6753143B2 (en) | 2000-05-01 | 2004-06-22 | Clinical Micro Sensors, Inc. | Target analyte detection using asymmetrical self-assembled monolayers |
DE102006038231A1 (de) * | 2006-08-07 | 2008-02-14 | Biotronik Vi Patent Ag | Implantat aus einem biokorrodierbaren metallischen Werkstoff mit einer Beschichtung aus einer Organosiliziumverbindung |
FR2943344B1 (fr) * | 2009-03-18 | 2011-04-15 | Commissariat Energie Atomique | Nouveaux composes silanes porteurs d'une chaine carbonee cyclique comprenant une fonction alcyne pour fonctionnaliser des supports solides et immobiliser sur ces supports des molecules biologiques |
WO2011089267A1 (en) * | 2010-01-25 | 2011-07-28 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Silylated biomolecules |
CN101845814B (zh) * | 2010-05-18 | 2011-08-17 | 金文成 | 具有自监测功能的复合材料智能锚具及其制备方法 |
JP5751580B2 (ja) * | 2011-04-28 | 2015-07-22 | 国立研究開発法人産業技術総合研究所 | メトキシオリゴエチレングリコール−シラン化合物表面修飾材料 |
CN105061489B (zh) | 2015-08-25 | 2019-03-05 | 深圳市华星光电技术有限公司 | 一种支化型有机硅材料及制备液晶面板的方法 |
JP7104911B2 (ja) * | 2018-01-31 | 2022-07-22 | 国立研究開発法人産業技術総合研究所 | 標的物質検出方法及び導波モードセンサ |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE8200442L (sv) * | 1982-01-27 | 1983-07-28 | Forsvarets Forsknings | Forfarande vid detektion av organiska molekyler, sasom biomolekyler |
JPH01181790A (ja) * | 1988-01-18 | 1989-07-19 | Toray Silicone Co Ltd | 生理活性物質の固定化方法 |
EP0337081A1 (en) * | 1988-03-31 | 1989-10-18 | Bio-Rad Laboratories, Inc. | Biospecific assay using a derivatized glass surface |
DD285099A5 (de) * | 1989-06-20 | 1990-12-05 | Klinikum Berlin Buch,Dd | Verfahren zur aktivierung von polystyren-festkoerperflaechen |
DE4039677A1 (de) * | 1990-12-12 | 1992-06-17 | Boehringer Mannheim Gmbh | Universalbindefilm |
DE4435728A1 (de) * | 1994-01-19 | 1995-07-20 | Boehringer Mannheim Gmbh | Biotinsilan-Verbindungen und diese Verbindungen enthaltende Bindematrix |
-
1995
- 1995-01-18 EP EP95100632A patent/EP0664452B1/de not_active Expired - Lifetime
- 1995-01-18 ES ES95100632T patent/ES2179853T3/es not_active Expired - Lifetime
- 1995-01-18 AT AT95100632T patent/ATE221660T1/de not_active IP Right Cessation
- 1995-01-19 JP JP00677095A patent/JP3214795B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
ATE221660T1 (de) | 2002-08-15 |
JPH07260790A (ja) | 1995-10-13 |
EP0664452B1 (de) | 2002-07-31 |
EP0664452A2 (de) | 1995-07-26 |
EP0664452A3 (de) | 1996-10-23 |
JP3214795B2 (ja) | 2001-10-02 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES2179853T3 (es) | Compuestos de biotina-silanos y matriz de fijacion que contiene estos compuestos. | |
HK1013653A1 (en) | Electroluminescent compounds and intermediates in their synthesis | |
DE58909458D1 (de) | Antigenkonstrukte von "Major Histocompatibility Complex" Klasse I Antigenen mit spezifischen Trägermolekülen, ihre Herstellung und Verwendung. | |
ATE82525T1 (de) | Kieseltraeger. | |
DE68911397T2 (de) | Radiohalogenierte Verbindungen für Markierung von spezifischen Stellen. | |
ATE142340T1 (de) | Universalbindefilm | |
AU4769085A (en) | Carrier material for use in immune determinations | |
DE3777773D1 (de) | Verfahren zur bestimmung von hyaluronsaeure. | |
FI862869A (fi) | Oeverdragna fasta kroppar foer bindande av aemnen med biologisk affinitet, deras framstaellningsfoerfarande och deras anvaendning. | |
DK226986D0 (da) | Radiohalogenerede smaa molekyler til proteinmaerkning | |
DE69221826T2 (de) | Aufgetragene Mikrokugeln | |
EP0289187A3 (en) | Vinyl substituted radiohalogen conjugates for protein labeling | |
DK0789763T3 (da) | ICAM-4-materialer og fremgangsmåder | |
AU647449B2 (en) | Method for the immunological determination of ligands | |
SE8500339L (sv) | Berarbundet histamin, dess framstellning och anvendning |