ES2174094T3 - Utilizacion de diaminas aliciclicas como inmunomoduladores. - Google Patents
Utilizacion de diaminas aliciclicas como inmunomoduladores.Info
- Publication number
- ES2174094T3 ES2174094T3 ES96927741T ES96927741T ES2174094T3 ES 2174094 T3 ES2174094 T3 ES 2174094T3 ES 96927741 T ES96927741 T ES 96927741T ES 96927741 T ES96927741 T ES 96927741T ES 2174094 T3 ES2174094 T3 ES 2174094T3
- Authority
- ES
- Spain
- Prior art keywords
- benzyl
- group
- substituted
- trihalomethyl
- aliciclic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
- A61P33/12—Schistosomicides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Tropical Medicine & Parasitology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Emergency Medicine (AREA)
- Virology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Hematology (AREA)
- AIDS & HIV (AREA)
- Molecular Biology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Plural Heterocyclic Compounds (AREA)
- Saccharide Compounds (AREA)
Abstract
UTILIZACION DE UN COMPUESTO QUE RESPONDE A LA FORMULA DE ESTRUCTURA GENERAL (I): R EPRESENTA UN RADICAL DIVALENTE QUE RESPONDE A LAS FORMULAS (II A V); EL SIMBOLO K REPRESENTA UN GRUPO METILENO O, CUANDO EL SIMBOLO Q ESTA REPRESENTADO POR LA FORMULA (II), UNA VALENCIA DE ENLACE. EL SIMBOLO R ES UN RADICAL ELEGIDO EN EL GRUPO FORMADO POR LOS RADICALES SIGUIENTES: BENCILO, BENCILO SUSTITUIDO POR UN HALOGENO O POR GRUPOS TRIHALOMETILO, BENCIL TRIHALOMETIL SUSTITUIDO, INDANILO, ALQUILO, CICLOALQUILO, CICLOALQUILALQUILO, ALCENILO, CICLOALCENILALQUILO, BICICLOALQUILO, BICICLOALCENILALQUILO, BICICLOALQUILALQUILO Y SUS SALES DE ADICION CON ACIDOS MINERALES U ORGANICOS; PREPARACION DE UN MEDICAMENTO DESTINADO A CORREGIR LA EXPRESION DE LOS GENES DE LAS CITOQUINAS Y/O DE SU RECEPTOR EN CASO DE DISFUNCION VINCULADA CON UNA PATOLOGIA DE ORIGEN EXOGENO O ENDOGENO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9509459A FR2737409B1 (fr) | 1995-08-03 | 1995-08-03 | Nouvelles utilisations de diamines alticycliques |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2174094T3 true ES2174094T3 (es) | 2002-11-01 |
Family
ID=9481683
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES96927741T Expired - Lifetime ES2174094T3 (es) | 1995-08-03 | 1996-08-02 | Utilizacion de diaminas aliciclicas como inmunomoduladores. |
Country Status (13)
Country | Link |
---|---|
US (1) | US6228890B1 (es) |
EP (1) | EP0841909B1 (es) |
JP (1) | JP4037450B2 (es) |
CN (1) | CN1121214C (es) |
AT (1) | ATE214273T1 (es) |
AU (1) | AU6745096A (es) |
BR (1) | BR9610077A (es) |
CA (1) | CA2228689A1 (es) |
DE (1) | DE69619827T2 (es) |
ES (1) | ES2174094T3 (es) |
FR (1) | FR2737409B1 (es) |
PT (1) | PT841909E (es) |
WO (1) | WO1997005859A2 (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2003286701B2 (en) * | 2002-10-30 | 2008-12-18 | Merck Sharp & Dohme Corp. | Tetrahydropyranyl cyclopentyl benzylamide modulators of chemokine receptor activity |
CN112691094B (zh) * | 2019-10-22 | 2022-09-23 | 中国科学院分子细胞科学卓越创新中心 | 防治病毒的新型化合物及其应用 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3202712A (en) * | 1963-02-05 | 1965-08-24 | American Home Prod | 1-cyclohexene-4-bis (omicron-chlorobenzylaminomethyl) and derivatives |
US3244750A (en) * | 1963-12-06 | 1966-04-05 | American Home Prod | Nu, nu'-disubstituted-aliphatic-bis-aminomethyl-cyclohexane derivatives |
FR1387971A (fr) * | 1962-12-21 | 1965-02-05 | Ayerst Mckenna & Harrison | Nouvelles diamines alicycliques et leur procédé de préparation |
US4060639A (en) * | 1976-05-14 | 1977-11-29 | Merck & Co., Inc. | Broad spectrum antibacterial compositions containing tris-(hydroxymethyl)-aminoethane and dicycloaliphatic-alkyl polyamines |
US5116823A (en) * | 1990-02-27 | 1992-05-26 | Roger Williams General Hospital | Drug combinations containing AZT |
-
1995
- 1995-08-03 FR FR9509459A patent/FR2737409B1/fr not_active Expired - Fee Related
-
1996
- 1996-08-02 US US09/011,145 patent/US6228890B1/en not_active Expired - Lifetime
- 1996-08-02 DE DE69619827T patent/DE69619827T2/de not_active Expired - Lifetime
- 1996-08-02 WO PCT/FR1996/001242 patent/WO1997005859A2/fr active IP Right Grant
- 1996-08-02 JP JP50817797A patent/JP4037450B2/ja not_active Expired - Fee Related
- 1996-08-02 EP EP96927741A patent/EP0841909B1/fr not_active Expired - Lifetime
- 1996-08-02 BR BR9610077A patent/BR9610077A/pt not_active Application Discontinuation
- 1996-08-02 CA CA002228689A patent/CA2228689A1/fr not_active Abandoned
- 1996-08-02 AU AU67450/96A patent/AU6745096A/en not_active Abandoned
- 1996-08-02 PT PT96927741T patent/PT841909E/pt unknown
- 1996-08-02 AT AT96927741T patent/ATE214273T1/de active
- 1996-08-02 CN CN96196531A patent/CN1121214C/zh not_active Expired - Fee Related
- 1996-08-02 ES ES96927741T patent/ES2174094T3/es not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
PT841909E (pt) | 2002-08-30 |
EP0841909A2 (fr) | 1998-05-20 |
BR9610077A (pt) | 1999-03-02 |
ATE214273T1 (de) | 2002-03-15 |
AU6745096A (en) | 1997-03-05 |
FR2737409A1 (fr) | 1997-02-07 |
CN1193910A (zh) | 1998-09-23 |
EP0841909B1 (fr) | 2002-03-13 |
CA2228689A1 (fr) | 1997-02-20 |
US6228890B1 (en) | 2001-05-08 |
JP4037450B2 (ja) | 2008-01-23 |
FR2737409B1 (fr) | 1997-10-24 |
JPH11510803A (ja) | 1999-09-21 |
DE69619827T2 (de) | 2002-11-07 |
WO1997005859A3 (fr) | 1997-03-27 |
DE69619827D1 (de) | 2002-04-18 |
WO1997005859A2 (fr) | 1997-02-20 |
CN1121214C (zh) | 2003-09-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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