ES2169051T3 - Procedimiento y aparato para ensayo inmunologico de aglutinacion indirecta. - Google Patents
Procedimiento y aparato para ensayo inmunologico de aglutinacion indirecta.Info
- Publication number
- ES2169051T3 ES2169051T3 ES94107640T ES94107640T ES2169051T3 ES 2169051 T3 ES2169051 T3 ES 2169051T3 ES 94107640 T ES94107640 T ES 94107640T ES 94107640 T ES94107640 T ES 94107640T ES 2169051 T3 ES2169051 T3 ES 2169051T3
- Authority
- ES
- Spain
- Prior art keywords
- crisol
- aglutination
- pattern
- indirect
- procedure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000000034 method Methods 0.000 title abstract 2
- 238000001556 precipitation Methods 0.000 abstract 3
- 239000002245 particle Substances 0.000 abstract 2
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
- G01N21/82—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a precipitate or turbidity
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54326—Magnetic particles
- G01N33/54333—Modification of conditions of immunological binding reaction, e.g. use of more than one type of particle, use of chemical agents to improve binding, choice of incubation time or application of magnetic field during binding reaction
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
- G01N35/028—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having reaction cells in the form of microtitration plates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/0098—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/805—Optical property
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/806—Electrical property or magnetic property
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/807—Apparatus included in process claim, e.g. physical support structures
- Y10S436/809—Multifield plates or multicontainer arrays
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Plasma & Fusion (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Optical Measuring Cells (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
UN METODO DE INMUNOENSAYO DE AGLUTINACION INCLUYE PERMITIR QUE PARTICULAS DE UN REACTIVO PARA INMUNOENSAYO SE PRECIPITEN EN FONDOS DE AL MENOS UN CRISOL, INCLINANDO EL CRISOL EN UN ANGULO DETERMINADO, PARA FORMAR UN PATRON DE PRECIPITACION, DEBIDO A UN FLUJO DE LAS PARTICULAS EN EL FONDO DEL CRISOL, DEBIDO A UN FLUJO DE PARTICULAS, MOVIENDO RELATIVAMENTE EL CRISOL Y UN SENSOR EN DIRECCION SUSTANCIALMENTE VERTICAL RESPECTO A UNA DIRECCION DE FLUJO DEL PATRON DE PRECIPITACION FORMADO, MIDIENDO LAS LONGITUDES DEL PATRON DE PRECIPITACION FORMADO EN UNA PLURALIDAD DE SECCIONES, DENTRO DEL ALCANCE DEL CRISOL, Y CONSIDERANDO EL SUCESO DE UNA INMUNORREACCION BASADA EN LOS VALORES DE LA LONGITUD MEDIDA DE LOS PATRONES DE PRECIPITACION.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP13908293A JPH06324042A (ja) | 1993-05-17 | 1993-05-17 | 間接凝集免疫測定法及びその装置 |
JP5139076A JP2809047B2 (ja) | 1993-05-17 | 1993-05-17 | 間接凝集免疫測定法及びこれに用いる沈降パターン測定装置 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2169051T3 true ES2169051T3 (es) | 2002-07-01 |
Family
ID=26471979
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES94107640T Expired - Lifetime ES2169051T3 (es) | 1993-05-17 | 1994-05-17 | Procedimiento y aparato para ensayo inmunologico de aglutinacion indirecta. |
Country Status (8)
Country | Link |
---|---|
US (1) | US6124139A (es) |
EP (1) | EP0625708B1 (es) |
KR (1) | KR0166111B1 (es) |
AU (1) | AU686604B2 (es) |
CA (1) | CA2123644C (es) |
DE (1) | DE69429206T2 (es) |
ES (1) | ES2169051T3 (es) |
TW (1) | TW351766B (es) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6046585A (en) * | 1997-11-21 | 2000-04-04 | Quantum Design, Inc. | Method and apparatus for making quantitative measurements of localized accumulations of target particles having magnetic particles bound thereto |
ATE334398T1 (de) * | 2000-09-05 | 2006-08-15 | Tecan Trading Ag | Träger für eine mikrotiterplatte |
US6518747B2 (en) | 2001-02-16 | 2003-02-11 | Quantum Design, Inc. | Method and apparatus for quantitative determination of accumulations of magnetic particles |
US7633398B2 (en) * | 2005-11-19 | 2009-12-15 | Noonan Technologies, Llc | Apparatus and method for measuring precipitation |
EP2394175B1 (en) | 2009-02-09 | 2016-02-03 | caprotec bioanalytics GmbH | Devices, systems and methods for separating magnetic particles |
GB2472252A (en) * | 2009-07-31 | 2011-02-02 | Simon Stafford | Microplate holder for inclining a microplate |
US8815610B2 (en) * | 2010-10-15 | 2014-08-26 | International Business Machines Corporation | Magnetic nanoparticle detection across a membrane |
FR2999012B1 (fr) * | 2012-11-30 | 2017-12-15 | Primadiag S A S | Module d'attraction magnetique, robot comprenant un tel module, et procede d'utilisation sur billes magnetiques d'un tel module ou d'un tel robot |
GB2542329B (en) * | 2015-07-07 | 2020-02-19 | Bee Robotics Ltd | Analysis Apparatus |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB215725A (en) * | 1923-05-07 | 1925-07-31 | Vickers Electrical Co Ltd | Improvements relating to electrical resistors and to the manufacture of the same |
CH588700A5 (es) * | 1975-02-28 | 1977-06-15 | Hoffmann La Roche | |
FI56905C (fi) * | 1978-02-28 | 1980-04-10 | Osmo A Suovaniemi | Foerfarande och anordning foer automatisk maetning av agglutinationsprov t ex i spektrofotometer adsoptionsfotometer fluorometer eller nefelometer |
JPS5933856B2 (ja) * | 1979-10-09 | 1984-08-18 | オリンパス光学工業株式会社 | 凝集反応測定方法およびそれに用いる反応容器 |
JPS61501162A (ja) * | 1983-11-21 | 1986-06-12 | ラブシステムズ オイ | 凝集反応結果の決定方法 |
JPS61228355A (ja) * | 1985-04-03 | 1986-10-11 | Green Cross Corp:The | 凝集反応の自動検出方法及び装置 |
DE3889261D1 (de) * | 1987-07-31 | 1994-06-01 | Fujirebio Kk | Gerät zur automatischen immunologischen Analyse. |
EP0351857B1 (en) * | 1988-07-20 | 1994-11-30 | Olympus Optical Co., Ltd. | Immunoassay method using magnetic marker particles |
CA2015941A1 (en) * | 1989-05-03 | 1990-11-03 | Marsha A. Kessler | Method of forming agglutinates in blood samples |
CA2028995A1 (en) * | 1989-10-31 | 1991-05-01 | Tomo Saito | Indirect agglutination immunoassay and apparatus therefor |
US5169601A (en) * | 1990-04-27 | 1992-12-08 | Suzuki Motor Corporation | Immunological agglutination detecting apparatus with separately controlled supplementary light sources |
WO1992005443A1 (en) * | 1990-09-15 | 1992-04-02 | Medical Research Council | Reagent separation |
JPH0792459B2 (ja) * | 1991-06-18 | 1995-10-09 | オリンパス光学工業株式会社 | 免疫学的試験方法 |
-
1994
- 1994-05-16 TW TW083104397A patent/TW351766B/zh active
- 1994-05-16 AU AU63107/94A patent/AU686604B2/en not_active Ceased
- 1994-05-16 KR KR1019940010606A patent/KR0166111B1/ko not_active IP Right Cessation
- 1994-05-16 CA CA002123644A patent/CA2123644C/en not_active Expired - Fee Related
- 1994-05-17 DE DE69429206T patent/DE69429206T2/de not_active Expired - Fee Related
- 1994-05-17 ES ES94107640T patent/ES2169051T3/es not_active Expired - Lifetime
- 1994-05-17 EP EP94107640A patent/EP0625708B1/en not_active Expired - Lifetime
-
1997
- 1997-09-19 US US08/933,583 patent/US6124139A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP0625708A2 (en) | 1994-11-23 |
CA2123644C (en) | 2002-03-26 |
KR0166111B1 (ko) | 1999-05-01 |
EP0625708B1 (en) | 2001-11-28 |
AU686604B2 (en) | 1998-02-12 |
TW351766B (en) | 1999-02-01 |
EP0625708A3 (en) | 1995-10-11 |
CA2123644A1 (en) | 1994-11-18 |
DE69429206T2 (de) | 2002-07-18 |
US6124139A (en) | 2000-09-26 |
AU6310794A (en) | 1994-11-24 |
DE69429206D1 (de) | 2002-01-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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