ES2165930T3 - 6-h-1,3,4-tiadiazin-2-amina sustituidos, su empleo como agentes anestesicos, cardiovasculares e hipometabolicos, y composicion farmaceutica que los contiene. - Google Patents

6-h-1,3,4-tiadiazin-2-amina sustituidos, su empleo como agentes anestesicos, cardiovasculares e hipometabolicos, y composicion farmaceutica que los contiene.

Info

Publication number
ES2165930T3
ES2165930T3 ES95944777T ES95944777T ES2165930T3 ES 2165930 T3 ES2165930 T3 ES 2165930T3 ES 95944777 T ES95944777 T ES 95944777T ES 95944777 T ES95944777 T ES 95944777T ES 2165930 T3 ES2165930 T3 ES 2165930T3
Authority
ES
Spain
Prior art keywords
cardiovascular
substituted
tiadiazin
amina
anesthetic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95944777T
Other languages
English (en)
Inventor
Oleg Nikolaevich Chupakhin
Larisa Petrovna Sidorova
Emma Afanasievna Tarakhty
Antonina Petrovna Novikova
Natalya Mikhailovna Perova
Valentin Antonovich Vinogradov
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
N T PREDPR LIGAND OBSCHESTVO S
Original Assignee
N T PREDPR LIGAND OBSCHESTVO S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by N T PREDPR LIGAND OBSCHESTVO S filed Critical N T PREDPR LIGAND OBSCHESTVO S
Application granted granted Critical
Publication of ES2165930T3 publication Critical patent/ES2165930T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/15—Six-membered rings
    • C07D285/16—Thiadiazines; Hydrogenated thiadiazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

LA INVENCION SE REFIERE A 6H - 1,3,4 - TADIAZIN - 2 - AMINAS, REPRESENTADAS POR LA SIGUIENTE FORMULA GENERAL: DONDE REPRESENTA UNA FRACCION MORFOLINO, TIOMORFOLINO, PIPERIDINO, PIRROLIDINO O HEXAMETILENIMINO, ASI COMO LAS SALES FARMACEUTICAMENTE ACEPTABLES DE DICHOS COMPUESTOS Y LA UTILIZACION DE LOS MISMOS COMO AGENTES ANESTESICOS, CARDIOVASCULARES E HIPOMETABOLICOS Y LAS COMPOSICIONES FARMACEUTICAS QUE LOS CONTIENEN.
ES95944777T 1995-12-28 1995-12-28 6-h-1,3,4-tiadiazin-2-amina sustituidos, su empleo como agentes anestesicos, cardiovasculares e hipometabolicos, y composicion farmaceutica que los contiene. Expired - Lifetime ES2165930T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/RU1995/000286 WO1997024353A1 (fr) 1995-12-28 1995-12-28 6-h-1,3,4-thiadiazine-2-amines substitues, leur utilisation en qualite d'agents anesthesiques, cardio-vasculaires et hypometaboliques, et composition pharmaceutique les contenant

Publications (1)

Publication Number Publication Date
ES2165930T3 true ES2165930T3 (es) 2002-04-01

Family

ID=20129974

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95944777T Expired - Lifetime ES2165930T3 (es) 1995-12-28 1995-12-28 6-h-1,3,4-tiadiazin-2-amina sustituidos, su empleo como agentes anestesicos, cardiovasculares e hipometabolicos, y composicion farmaceutica que los contiene.

Country Status (8)

Country Link
US (1) US6028068A (es)
EP (1) EP0877025B1 (es)
JP (1) JP2000515118A (es)
AT (1) ATE206923T1 (es)
AU (1) AU5128096A (es)
DE (1) DE69523346T2 (es)
ES (1) ES2165930T3 (es)
WO (1) WO1997024353A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6738661B1 (en) * 1999-10-22 2004-05-18 Biosynergetics, Inc. Apparatus and methods for the controllable modification of compound concentration in a tube

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4988889A (es) * 1972-12-29 1974-08-24
ZA804555B (en) * 1979-09-04 1981-09-30 Richardson Merrell Inc 5-(optionally substituted phenyl)-6h-1,3,4-thiadiazine-2-amines
US4309426A (en) * 1979-09-04 1982-01-05 Richardson-Merrell Inc. Muscle-relaxant 1,3,4-thiadiazin-2-amines
US4272532A (en) * 1979-09-04 1981-06-09 Richardson-Merrell Inc. 5-(Optionally substituted phenyl)-6H-1,3,4-thiadiazine-2-amines
US4289767A (en) * 1979-09-04 1981-09-15 Richardson-Merrell Inc. 5-(Chlorophenyl)-6H-1,3,4-thiadiazine-2-amines
GB2086879B (en) * 1980-11-04 1984-07-18 Richardson Merrell Inc 5-aryl-6h-1,3,4-thiadiazine-2-amines
DE3042295A1 (de) * 1980-11-08 1982-06-09 Richardson-Merrell Inc., Wilton, Conn. Substituierte 6h-1,3,4-thiadiazin-2-amine, verfahren zu ihrer herstellung und ihre verwendung
FR2493844A1 (fr) * 1980-11-12 1982-05-14 Richardson Merrell Inc Nouvelles 5-(phenyl facultativement substitue)-6h-1,3,4-thiadiazine-2-amines, utiles notamment comme relaxants musculaires, et leur procede de preparation
CA1199027A (en) * 1981-11-12 1986-01-07 Stuart D. Mills Heterocyclic derivatives of pyridazinone, thiadiazinone, oxadiazinone and triazinone
DD220311A1 (de) * 1983-12-29 1985-03-27 Univ Ernst Moritz Arndt Verfahren zur synthese von 1-phenyl-2-(n-methyl-n-(6h-1,3,4-thiadiazin-2-yl)-amino)-propan-1-olen
DD228248A1 (de) * 1984-11-07 1985-10-09 Univ Ernst Moritz Arndt Verfahren zur synthese von pyrazolen
DE3702756A1 (de) * 1987-01-30 1988-08-11 Hoechst Ag 5-(3-alkyl-5-tert.butyl-4-hydroxyphenyl)-2- amino-6h-1,3,4-thiadiazine, verfahren zu ihrer herstellung, die sie enthaltenden arzneimittel und ihre verwendung
GB2215206B (en) * 1988-02-29 1991-07-03 Farmos Oy 4-substituted imidazole derivatives useful in perioperative care
US5021413B1 (en) * 1988-08-24 1994-12-13 Sankyo Co Analgesic thiomorpholins, their preparation, and pharmaceutical compositions containing them
SU1726478A1 (ru) * 1990-04-09 1992-04-15 Уральский политехнический институт им.С.М.Кирова 2-Гексаметиленимино-5-(4-бромфенил)-6Н-1,3,4-тиадиазин гидроиодид, обладающий контрацептивной активностью
DE4141218A1 (de) * 1991-12-13 1993-06-17 Luitpold Werk Chem Pharm Thiadiazincarbonsaeureamidderivate, verfahren zu ihrer herstellung und arzneimittel
AU4288293A (en) * 1992-04-27 1993-11-29 E.I. Du Pont De Nemours And Company Fungicidal 1,3,4-oxadiazines and 1,3,4-thiadiazines
JP3160787B2 (ja) * 1993-03-03 2001-04-25 株式会社アイホー 連続式米飯冷却装置
RU2058307C1 (ru) * 1994-03-01 1996-04-20 Научно-технологическое предприятие "Лиганд" Соли 2-морфолино-5-фенил-6н-1,3,4-тиадиазина и 4,7-дигидро-6-нитро-7-оксо-[1,2,4]-триазоло [5,1-с] [1,2,4]-триазинов, обладающие бактерицидной активностью в отношении возбудителя микоплазмоза

Also Published As

Publication number Publication date
EP0877025A4 (en) 1999-03-31
EP0877025A1 (en) 1998-11-11
DE69523346D1 (de) 2001-11-22
AU5128096A (en) 1997-07-28
WO1997024353A1 (fr) 1997-07-10
US6028068A (en) 2000-02-22
JP2000515118A (ja) 2000-11-14
ATE206923T1 (de) 2001-11-15
DE69523346T2 (de) 2002-08-29
EP0877025B1 (en) 2001-10-17

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