ES2165275A1 - Certificado de adicion de la patente es9700099 obtencion de nuevos cristales liquidos polimeros capaces de interaccionar con liposomas. - Google Patents
Certificado de adicion de la patente es9700099 obtencion de nuevos cristales liquidos polimeros capaces de interaccionar con liposomas.Info
- Publication number
- ES2165275A1 ES2165275A1 ES009901362A ES9901362A ES2165275A1 ES 2165275 A1 ES2165275 A1 ES 2165275A1 ES 009901362 A ES009901362 A ES 009901362A ES 9901362 A ES9901362 A ES 9901362A ES 2165275 A1 ES2165275 A1 ES 2165275A1
- Authority
- ES
- Spain
- Prior art keywords
- liposomes
- liquid crystals
- interaction
- production
- polymer liquid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
- C09K19/00—Liquid crystal materials
- C09K19/04—Liquid crystal materials characterised by the chemical structure of the liquid crystal components, e.g. by a specific unit
- C09K19/38—Polymers
- C09K19/3804—Polymers with mesogenic groups in the main chain
- C09K19/3809—Polyesters; Polyester derivatives, e.g. polyamides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
- Y10T428/2984—Microcapsule with fluid core [includes liposome]
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Crystallography & Structural Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Liquid Crystal Substances (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Obtención de nuevos cristales líquidos polímeros capaces de interaccionar con liposomas. a. Adición simultánea de polímero cristal líquido colestérico, de molécula helicoidal, tales como PTOBEE (C{sub,26}H{sub,20}O{sub,8}){sub,n} y PTOBDME (C{sub,34}H{sub,36}O{sub,8}){sub,n} a un lípido anhidro con posterior hidratación, agitación y formación de liposomas (Multicapas) ó (Bicapas, por extrusión) con inserción de la molécula helicoidal de polímero cristal líquido a la bicapa lipídica; b. Interacción selectiva del polímero quiral frente a liposomas de lípido según sea dicho lípido racémico ó enantiómero. Cuando el polímero cristal líquido colestérico es añadido a liposomas de lípido enantiómero, se obtiene una estructura donde no se observan transiciones de fase con la temperatura.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES009700099A ES2125817B1 (es) | 1997-01-20 | 1997-01-20 | Obtencion de nuevos cristales liquidos polimeros capaces de interaccionar con liposomas. |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2165275A1 true ES2165275A1 (es) | 2002-03-01 |
ES2165275B1 ES2165275B1 (es) | 2003-10-16 |
Family
ID=8297921
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES009700099A Expired - Fee Related ES2125817B1 (es) | 1997-01-20 | 1997-01-20 | Obtencion de nuevos cristales liquidos polimeros capaces de interaccionar con liposomas. |
ES009901362A Expired - Fee Related ES2165275B1 (es) | 1997-01-20 | 1999-06-18 | Obtencion de nuevos cristales liquidos polimeros capaces de interaccionar con liposomas |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES009700099A Expired - Fee Related ES2125817B1 (es) | 1997-01-20 | 1997-01-20 | Obtencion de nuevos cristales liquidos polimeros capaces de interaccionar con liposomas. |
Country Status (7)
Country | Link |
---|---|
US (1) | US6277403B1 (es) |
EP (1) | EP0966959A1 (es) |
JP (1) | JP2001514616A (es) |
AU (1) | AU738141B2 (es) |
CA (1) | CA2278567A1 (es) |
ES (2) | ES2125817B1 (es) |
WO (1) | WO1998031347A1 (es) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7230088B2 (en) | 2001-07-03 | 2007-06-12 | Mallinckrodt, Inc. | Compounds for dual photodiagnosis and therapy |
US6673334B1 (en) * | 2000-10-16 | 2004-01-06 | Mallinkcrodt, Inc. | Light sensitive compounds for instant determination of organ function |
US6669926B1 (en) * | 2000-10-16 | 2003-12-30 | Mallinckrodt, Inc. | Hydrophilic light absorbing indole compounds for determination of physiological function in critically ill patients |
WO2007106436A2 (en) * | 2006-03-10 | 2007-09-20 | Mallinckrodt Inc. | Photoactive compounds and compositions and uses thereof |
WO2007149479A1 (en) | 2006-06-22 | 2007-12-27 | Mallinckrodt Inc. | Pyrazine derivatives and uses thereof in renal monitoring |
US8664392B2 (en) | 2004-12-23 | 2014-03-04 | Medibeacon, LLC | Pyrazine derivatives for bioconjugation |
JP2009528373A (ja) * | 2006-03-02 | 2009-08-06 | マリンクロッド・インコーポレイテッド | チアジアゾール化合物および光線療法のためのその使用 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1994020073A1 (en) * | 1993-03-03 | 1994-09-15 | Liposome Technology, Inc. | Lipid-polymer conjugates and liposomes |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4999348A (en) * | 1987-12-11 | 1991-03-12 | Estee Lauder Inc. | Liquid crystal containing cosmetic and pharmaceutical compositions and methods for utilizing such compositions |
EP0486437B1 (en) | 1990-11-13 | 1997-07-09 | ISTITUTO SIEROVACCINOGENO ITALIANO I.S.I. S.p.A. | Functional polyesters from glycidyl derivatives and cyclic anhydrides or carbon dioxide |
IT1242214B (it) | 1990-11-13 | 1994-03-03 | Emo Chiellini | Derivati polifunzionali delle ciclodestrine |
IT1244511B (it) | 1991-04-15 | 1994-07-15 | Isi Ist Sierovaccinogeno Ital | Idrogeli a base di policarbossilati sintetici e proteine per il rilascio controllato di farmaci e procedimento per la loro preparazione. |
FR2689418B1 (fr) * | 1992-04-03 | 1994-07-01 | Centre Nat Rech Scient | Procede de preparation de micro-capsules ou de liposomes de tailles controlees par application d'un cisaillement constant sur une phase lamellaire. |
JP3308010B2 (ja) * | 1992-12-15 | 2002-07-29 | ポーラ化成工業株式会社 | 被膜安定化リポソーム及びその製造方法 |
-
1997
- 1997-01-20 ES ES009700099A patent/ES2125817B1/es not_active Expired - Fee Related
-
1998
- 1998-01-16 WO PCT/ES1998/000005 patent/WO1998031347A1/es not_active Application Discontinuation
- 1998-01-16 JP JP53379598A patent/JP2001514616A/ja active Pending
- 1998-01-16 US US09/355,090 patent/US6277403B1/en not_active Expired - Fee Related
- 1998-01-16 EP EP98900282A patent/EP0966959A1/en not_active Withdrawn
- 1998-01-16 CA CA002278567A patent/CA2278567A1/en not_active Abandoned
- 1998-01-16 AU AU54862/98A patent/AU738141B2/en not_active Ceased
-
1999
- 1999-06-18 ES ES009901362A patent/ES2165275B1/es not_active Expired - Fee Related
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1994020073A1 (en) * | 1993-03-03 | 1994-09-15 | Liposome Technology, Inc. | Lipid-polymer conjugates and liposomes |
Non-Patent Citations (1)
Title |
---|
BASE DE DATOS CAPLUS en STN, AN 1996:718236 (CAS 126:80369). K. TAJIMA et al. "ESR study on DMPC and DMPG bylayers in the L-alpha phase". & LANGMUIR, Vol. 12. no. 26, 1996, paginas 6651-6658 * |
Also Published As
Publication number | Publication date |
---|---|
AU738141B2 (en) | 2001-09-06 |
JP2001514616A (ja) | 2001-09-11 |
ES2165275B1 (es) | 2003-10-16 |
US6277403B1 (en) | 2001-08-21 |
CA2278567A1 (en) | 1998-07-23 |
WO1998031347A1 (es) | 1998-07-23 |
ES2125817A1 (es) | 1999-03-01 |
ES2125817B1 (es) | 2000-01-01 |
AU5486298A (en) | 1998-08-07 |
EP0966959A1 (en) | 1999-12-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EC2A | Search report published |
Date of ref document: 20020301 Kind code of ref document: A1 Effective date: 20020301 |
|
FG2A | Definitive protection |
Ref document number: 2165275B1 Country of ref document: ES |
|
FD2A | Announcement of lapse in spain |
Effective date: 20190612 |