ES2163439T3 - Promotor de la osteogenesis y remedio contra la osteoporosis. - Google Patents

Promotor de la osteogenesis y remedio contra la osteoporosis.

Info

Publication number
ES2163439T3
ES2163439T3 ES94915264T ES94915264T ES2163439T3 ES 2163439 T3 ES2163439 T3 ES 2163439T3 ES 94915264 T ES94915264 T ES 94915264T ES 94915264 T ES94915264 T ES 94915264T ES 2163439 T3 ES2163439 T3 ES 2163439T3
Authority
ES
Spain
Prior art keywords
osteogenesis
promoter
osteoporosis
treating
morbid condition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94915264T
Other languages
English (en)
Inventor
Yasuo Suzuki
Yutaka Mizushima
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LTT Institute Co Ltd
Original Assignee
LTT Institute Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LTT Institute Co Ltd filed Critical LTT Institute Co Ltd
Application granted granted Critical
Publication of ES2163439T3 publication Critical patent/ES2163439T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/5685—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone having an oxo group in position 17, e.g. androsterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

UN PROMOTOR DE OSTEOGENESIS Y/O REMEDIO DE OSTEOPOROSIS QUE CONTIENE UN DERIVADO DE ANDROGENO REPRESENTADO POR LA FORMULA GENERAL (1) O UNA SAL DE ESTE COMO EL INGREDIENTE ACTIVO. EN DICHA FORMULA (1) LAS LINEAS DE PUNTOS INDICAN QUE LOS ENLACES QUE LO COMPRENDEN REPRESENTAN CADA UNO BIEN UN ENLACE SENCILLO O UN ENLACE DOBLE. EL COMPUESTO (1) ACTIVA OSTEOBLASTOS, PROMUEVE OSTEOGENESIS E INCREMENTA LA CANTIDAD OSEA, Y SE USA PARA TRATAR UNA CONDICION MORBIDA DE OSTEOGENESIS REDUCIDA DEBIDO AL ENVEJECIMIENTO, INMOVILIZACION, ADMINISTRACION DE GLUCOCORTICOIDES, ETC, ADEMAS PUEDE INCREMENTAR LA CANTIDAD OSEA POR SU EFECTO PROMOTOR DE OSTEOGENESIS Y DE MODO QUE ES UTIL PARA TRATAR LA OSTEOPOROSIS QUE ACOMPAÑA LA ANTERIOR CONDICION MORBIDA O QUE OCURRE DESPUES DE UNA OVARIOCTOMIA O MENOPAUSIA.
ES94915264T 1993-05-18 1994-05-18 Promotor de la osteogenesis y remedio contra la osteoporosis. Expired - Lifetime ES2163439T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP14969393 1993-05-18

Publications (1)

Publication Number Publication Date
ES2163439T3 true ES2163439T3 (es) 2002-02-01

Family

ID=15480752

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94915264T Expired - Lifetime ES2163439T3 (es) 1993-05-18 1994-05-18 Promotor de la osteogenesis y remedio contra la osteoporosis.

Country Status (11)

Country Link
US (1) US5565444A (es)
EP (1) EP0698612B1 (es)
JP (1) JP3197562B2 (es)
AT (1) ATE203544T1 (es)
AU (1) AU6657894A (es)
CA (1) CA2162604C (es)
DE (1) DE69427815T2 (es)
ES (1) ES2163439T3 (es)
GR (1) GR3036736T3 (es)
PT (1) PT698612E (es)
WO (1) WO1994026768A1 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999007381A1 (en) * 1997-08-11 1999-02-18 Weider Nutrition International, Inc. Compositions and treatments to reduce side effects of administration of androgenic testosterone precursors
US6579936B1 (en) 1998-07-30 2003-06-17 Dainippon Ink And Chemicals, Inc. Composition of polyarylenesulfide, epoxy resin and oxazoline polymer
WO2000019823A1 (en) * 1998-10-07 2000-04-13 The Board Of Trustees Of The University Of Arkansas Methods of screening for apoptosis-controlling agents for bone anabolic therapies and uses thereof
AU1525700A (en) 1998-11-19 2000-06-05 Board Of Trustees Of The University Of Arkansas, The Increasing bone strength with selected bisphosphonates
JP4490689B2 (ja) * 2001-10-03 2010-06-30 メルク・シャープ・エンド・ドーム・コーポレイション アンドロゲン受容体調節剤としてのアンドロスタン１７β−カルボキサミド類
EP1734963A4 (en) 2004-04-02 2008-06-18 Merck & Co Inc METHOD FOR TREATING PEOPLE WITH METABOLIC AND ANTHROPOMETRIC DISORDER
GB0409498D0 (en) * 2004-04-28 2004-06-02 Hunter Fleming Ltd Transdermal steroid formulation
GB0523550D0 (en) * 2005-11-18 2005-12-28 Hunter Fleming Ltd Therapeutic uses of steroidal compounds

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3271426A (en) * 1963-06-28 1966-09-06 Schering Corp Novel androstane oximino ethers and methods for their manufacture
US3741990A (en) * 1969-07-28 1973-06-26 Upjohn Co Organic compounds and processes
EP0496520A1 (en) * 1991-01-22 1992-07-29 Merck & Co. Inc. Novel bone acting agents
US5183815A (en) * 1991-01-22 1993-02-02 Merck & Co., Inc. Bone acting agents

Also Published As

Publication number Publication date
EP0698612A4 (en) 1998-05-27
ATE203544T1 (de) 2001-08-15
CA2162604A1 (en) 1994-11-24
DE69427815T2 (de) 2001-11-08
EP0698612B1 (en) 2001-07-25
GR3036736T3 (en) 2001-12-31
CA2162604C (en) 2002-09-17
EP0698612A1 (en) 1996-02-28
AU6657894A (en) 1994-12-12
JP3197562B2 (ja) 2001-08-13
US5565444A (en) 1996-10-15
PT698612E (pt) 2001-11-30
WO1994026768A1 (en) 1994-11-24
DE69427815D1 (de) 2001-08-30

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