ES2160991T3 - Procedimiento para la preparacion de sales de adicion de acido de 2-aminoetanosulfonilazida, del hidrocloruro de 2-aminoetanosulfonilazida asi como la utilizacion de las mismas. - Google Patents

Procedimiento para la preparacion de sales de adicion de acido de 2-aminoetanosulfonilazida, del hidrocloruro de 2-aminoetanosulfonilazida asi como la utilizacion de las mismas.

Info

Publication number
ES2160991T3
ES2160991T3 ES98103843T ES98103843T ES2160991T3 ES 2160991 T3 ES2160991 T3 ES 2160991T3 ES 98103843 T ES98103843 T ES 98103843T ES 98103843 T ES98103843 T ES 98103843T ES 2160991 T3 ES2160991 T3 ES 2160991T3
Authority
ES
Spain
Prior art keywords
aminoethanosulfonilazida
hydrochloride
preparation
acid addition
addition salts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES98103843T
Other languages
English (en)
Inventor
Claus Herdeis
Christian Edwin Weis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of ES2160991T3 publication Critical patent/ES2160991T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/48—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups having nitrogen atoms of sulfonamide groups further bound to another hetero atom
    • C07C311/49—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups having nitrogen atoms of sulfonamide groups further bound to another hetero atom to nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/02—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of sulfonic acids or halides thereof
    • C07C303/16—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of sulfonic acids or halides thereof by oxidation of thiols, sulfides, hydropolysulfides, or polysulfides with formation of sulfo or halosulfonyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/36—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/15—Six-membered rings
    • C07D285/16—Thiadiazines; Hydrogenated thiadiazines
    • C07D285/18—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

UN NUEVO PROCEDIMIENTO PARA LA PRODUCCION DE TAURINAMIDA O SUS SALES DE ADICION DE ACIDO Y LOS COMPUESTOS OBTENIDOS A PARTIR DE ESTOS TAUROLIDINA O TAURULTAM, EN EL QUE SE PARTE DE CISTEAMINA O CISTAMINA, ESPECIALMENTE EN FORMA DE SUS SALES DE ADICION DE ACIDO Y EN EL QUE SE VA OBTENIENDO COMO PRODUCTO INTERMEDIO CLAVE EL COMPUESTO 2 - AMINOETANSULFONILAZIDA, ESPECIALMENTE EN FORMA DE UNA SAL DE ADICION DE ACIDO SOLUBLE EN AGUA.
ES98103843T 1997-03-04 1998-03-04 Procedimiento para la preparacion de sales de adicion de acido de 2-aminoetanosulfonilazida, del hidrocloruro de 2-aminoetanosulfonilazida asi como la utilizacion de las mismas. Expired - Lifetime ES2160991T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19708782A DE19708782C1 (de) 1997-03-04 1997-03-04 Verfahren zur Herstellung von 2-Aminoethansulfonylazid-säureadditionssalzen, 2-Aminoethansulfonylazid-hydrochlorid sowie dessen Verwendung

Publications (1)

Publication Number Publication Date
ES2160991T3 true ES2160991T3 (es) 2001-11-16

Family

ID=7822201

Family Applications (1)

Application Number Title Priority Date Filing Date
ES98103843T Expired - Lifetime ES2160991T3 (es) 1997-03-04 1998-03-04 Procedimiento para la preparacion de sales de adicion de acido de 2-aminoetanosulfonilazida, del hidrocloruro de 2-aminoetanosulfonilazida asi como la utilizacion de las mismas.

Country Status (5)

Country Link
US (1) US5889183A (es)
EP (1) EP0863133B1 (es)
AT (1) ATE206112T1 (es)
DE (2) DE19708782C1 (es)
ES (1) ES2160991T3 (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8304390B2 (en) * 1997-07-31 2012-11-06 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Method of treatment for preventing or reducing tumor growth in the liver of patient
US20050124608A1 (en) * 2001-04-03 2005-06-09 Redmond H. P. Treatment of cancers
US20060199811A1 (en) * 1997-07-31 2006-09-07 Pfirrmann Rolf W Method of treatment for preventing or reducing tumor growth in the liver of patient
US6821968B2 (en) 2001-09-26 2004-11-23 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Stable taurolidine electrolyte solutions
US8030301B2 (en) * 1999-06-04 2011-10-04 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Treatment of cancers with methylol-containing compounds and at least one electrolyte
US7892530B2 (en) * 1999-06-04 2011-02-22 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Treatment of tumor metastases and cancer
US7345039B2 (en) * 1999-06-04 2008-03-18 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Enhancement of effectiveness of 5-fluorouracil in treatment of tumor metastases and cancer
AU2002252338B2 (en) * 2001-03-15 2007-09-13 Rhode Island Hospital, A Lifespan Partner Taurine compounds
DE10261241A1 (de) * 2002-12-20 2004-07-15 3M Espe Ag Dentalmaterial mit bakteriostatischen und/oder bakteriziden Substanzen
US20050008684A1 (en) * 2003-07-10 2005-01-13 Claus Herdeis Method of treatment for acne, rosacea and ulcers with taurolidine and/or taurultam in a pharmaceutical composition
US7696182B2 (en) 2004-11-02 2010-04-13 Nd Partners, Llc Antimicrobial locking solutions comprising taurinamide derivatives and biologically acceptable salts and acids, with the addition of small concentrations of heparin
EP1787627A1 (en) 2005-11-17 2007-05-23 3M Innovative Properties Company Anti-microbial dental impression material
EP1847248A1 (de) * 2006-04-21 2007-10-24 Schrader, Andreas, Dr. Kosmetische Mittel zum Schutz oder zur Regenerierung des Haares oder der Haut
EP1882476B1 (de) 2006-07-25 2008-11-19 HERDEIS, Claus Herstellung von antimikrobiellen Formulierungen unter Verwendung von 7-Oxa-2-thia 1,5-diazabicyclo[3.3.1]nonan-2,2-dion
WO2011053764A2 (en) 2009-11-02 2011-05-05 Plant Sensory Systems, Llc Method for the biosynthesis of taurine or hypotaurine in cells
DE102010010360A1 (de) 2010-03-05 2011-09-08 Gamptec Gmbh Formulierungen von Taurolidin und Verfahren zu seiner Herstellung
EP2643308B1 (en) 2010-11-23 2016-08-17 Biophore India Pharmaceuticals Pvt. Ltd. Process for the preparation of taurolidine and its intermediates thereof
ES2727077T3 (es) 2015-11-11 2019-10-14 Christian Edwin Weis Solución acuosa de productos de condensación de taurinamida y metilenglicol para su uso como agente antiinfeccioso en el implante de dispositivos electrónicos implantables y otros dispositivos en cirugía cardíaca
CN114539106B (zh) * 2022-03-15 2023-05-02 梯尔希（南京）药物研发有限公司 一种稳定同位素标记的牛磺酰胺盐酸盐的合成方法
US11738120B1 (en) 2022-04-14 2023-08-29 Cormedix Inc. Synthesis of taurolidine, purity profiles and polymorphs

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2184279A (en) * 1937-11-27 1939-12-26 Squibb & Sons Inc Amino-aliphatic sulphonamides and process for preparing them
GB1124285A (en) * 1964-10-06 1968-08-21 Geistlich Soehne Ag Novel perhydro-1,2,4-thiadiazine dioxides-(1,1), their preparation and compositionscontaining them
GB8328073D0 (en) * 1983-10-20 1983-11-23 Geistlich Soehne Ag Chemical compounds
DE3533612A1 (de) * 1985-09-20 1987-04-02 Johannes Reinmueller Neuartige verwendung von taurolin
GB8813033D0 (en) * 1988-06-02 1988-07-06 Geistlich Soehne Ag Chemical compound
DE19515976C1 (de) * 1995-05-02 1996-10-10 Claus Prof Dr Herdeis beta-Azidoethansulfonylazid, Verfahren zu seiner Herstellung und seine Verwendung in Verfahren zur Herstellung von Taurinamid und Taurolidin

Also Published As

Publication number Publication date
EP0863133A3 (de) 1998-12-09
US5889183A (en) 1999-03-30
DE59801561D1 (de) 2001-10-31
ATE206112T1 (de) 2001-10-15
EP0863133A2 (de) 1998-09-09
EP0863133B1 (de) 2001-09-26
DE19708782C1 (de) 1998-08-06

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