ES2159812T3 - Procedimiento de tratamiento de afecciones con agonistas de estrogeno. - Google Patents

Procedimiento de tratamiento de afecciones con agonistas de estrogeno.

Info

Publication number
ES2159812T3
ES2159812T3 ES97301150T ES97301150T ES2159812T3 ES 2159812 T3 ES2159812 T3 ES 2159812T3 ES 97301150 T ES97301150 T ES 97301150T ES 97301150 T ES97301150 T ES 97301150T ES 2159812 T3 ES2159812 T3 ES 2159812T3
Authority
ES
Spain
Prior art keywords
strogen
agonists
processing
excessive
affection
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97301150T
Other languages
English (en)
Inventor
David Burton Maclean
David Duane Thompson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Application granted granted Critical
Publication of ES2159812T3 publication Critical patent/ES2159812T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/472—Non-condensed isoquinolines, e.g. papaverine
    • A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4453—Non condensed piperidines, e.g. piperocaine only substituted in position 1, e.g. propipocaine, diperodon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Abstract

USO DE UN COMPUESTO DE LA FORMULA I, O DE UN ISOMERO OPTICO O GEOMETRICO DEL MISMO; O DE UNA SAL DE ADICION ACIDA ACEPTABLE FARMACEUTICAMENTE NO TOXICA, N-OXIDO, SAL DE AMONIO CUATERONARIO O ESTER DE LO ANTERIOR, PARA LA FABRICACION DE UN MEDICAMENTO QUE INHIBA UNA CONDICION PATOLOGICA COMO PUEDE SER LA ENFERMEDAD DE ALZHEIMER, SINDROME PREMENSTRUAL, SINDROME PERIMENOPAUSICO, DEFICIENCIA DE TROMBOMODULINA, FIBROSIS UTERINA, ACTIVIDAD DE MIELOPEROXIDASA EXCESIVA, TROMBINA EXCESIVA, ENFERMEDADES INMUNES, DAÑO POR REPERFUSION DE MIOCARDIO ISQUEMICO Y NIVEL INSUFICIENTE DE TETOSTERONA; DONDE: A SE SELECCIONA A PARTIR DE CH{SUB,2} Y NR; B,D Y E SE SELECCIONAN INDEPENDIENTEMENTE A PARTIR DE CH Y N; E Y, Z{SUP,1} Y G SON CIERTOS SUSTITUTIVOS ESPECIFICADOS.
ES97301150T 1996-02-28 1997-02-21 Procedimiento de tratamiento de afecciones con agonistas de estrogeno. Expired - Lifetime ES2159812T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1321396P 1996-02-28 1996-02-28

Publications (1)

Publication Number Publication Date
ES2159812T3 true ES2159812T3 (es) 2001-10-16

Family

ID=21758835

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97301150T Expired - Lifetime ES2159812T3 (es) 1996-02-28 1997-02-21 Procedimiento de tratamiento de afecciones con agonistas de estrogeno.

Country Status (18)

Country Link
US (1) US5889042A (es)
EP (1) EP0792642B1 (es)
JP (1) JPH107564A (es)
KR (1) KR970061256A (es)
CN (1) CN1165655A (es)
AT (1) ATE204475T1 (es)
AU (1) AU703384B2 (es)
CA (1) CA2198562C (es)
DE (1) DE69706209T2 (es)
DK (1) DK0792642T3 (es)
ES (1) ES2159812T3 (es)
GR (1) GR3036874T3 (es)
IL (1) IL120267A (es)
MX (1) MX9701605A (es)
MY (1) MY118765A (es)
PT (1) PT792642E (es)
TW (1) TW442286B (es)
ZA (1) ZA971713B (es)

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PA8576201A1 (es) * 2002-07-10 2004-05-26 Pfizer Prod Inc Composicion farmaceutica que tiene una distribucion y potencia uniforme de farmaco
BRPI0406596A (pt) * 2003-01-22 2005-12-20 Pfizer Prod Inc Métodos para tratar a dor articular e melhorar o sono utilizando um agonista/antagonista de estrogênio
US7459286B1 (en) * 2003-10-22 2008-12-02 The Cleveland Clinic Foundation Assessing the risk of a major adverse cardiac event in patients with chest pain
EP2306192B1 (en) 2003-12-05 2015-10-14 The Cleveland Clinic Foundation Risk Markers For Cardiovascular Disease
WO2006020498A2 (en) 2004-08-11 2006-02-23 The Cleveland Clinic Foundation Therapeutic agents and methods for cardiovascular disease
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US10426754B2 (en) * 2017-06-14 2019-10-01 Anavex Life Sciences Corp. Crystalline form of ANAVEX2-73 for the treatment of Alzheimer's disease

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Also Published As

Publication number Publication date
JPH107564A (ja) 1998-01-13
ATE204475T1 (de) 2001-09-15
GR3036874T3 (en) 2002-01-31
MY118765A (en) 2005-01-31
DE69706209D1 (de) 2001-09-27
ZA971713B (en) 1998-08-27
DE69706209T2 (de) 2001-12-06
KR970061256A (ko) 1997-09-12
MX9701605A (es) 1998-04-30
IL120267A0 (en) 1997-06-10
EP0792642B1 (en) 2001-08-22
US5889042A (en) 1999-03-30
CN1165655A (zh) 1997-11-26
AU703384B2 (en) 1999-03-25
DK0792642T3 (da) 2001-10-08
CA2198562A1 (en) 1997-08-28
CA2198562C (en) 2002-09-10
TW442286B (en) 2001-06-23
PT792642E (pt) 2001-12-28
AU1498097A (en) 1997-09-04
IL120267A (en) 2002-11-10
EP0792642A1 (en) 1997-09-03

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