ES2153387T3 - Composicion de agentes antineoplasticos incorporados en micelas. - Google Patents

Composicion de agentes antineoplasticos incorporados en micelas.

Info

Publication number
ES2153387T3
ES2153387T3 ES93922479T ES93922479T ES2153387T3 ES 2153387 T3 ES2153387 T3 ES 2153387T3 ES 93922479 T ES93922479 T ES 93922479T ES 93922479 T ES93922479 T ES 93922479T ES 2153387 T3 ES2153387 T3 ES 2153387T3
Authority
ES
Spain
Prior art keywords
micelas
composition
antineoplastic agents
agents incorporated
oxypropylene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93922479T
Other languages
English (en)
Inventor
Valery Yu Alakhov
Alexander V Kabanov
Peter G Sveshnikov
Eugenii S Severin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Supratek Pharma Inc
Original Assignee
Supratek Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Supratek Pharma Inc filed Critical Supratek Pharma Inc
Application granted granted Critical
Publication of ES2153387T3 publication Critical patent/ES2153387T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

COMPOSICIONES DE AGENTES ANTINEOPLASTICOS INCORPORAN EL AGENTE EN MICELAS DE, AL MENOS, UN COPOLIMERO EN BLOQUE DE POLI(OXIETILENO) POLI(OXIPROPILENO), EN EL QUE LA PROPORCION DE BLOQUES DE (OXIPROPILENO) A BLOQUES DE (OXIETILENO) ES DE 0''25 A 1''5 APROXIMADAMENTE, Y LAS MICELAS TIENEN UN DIAMETRO MEDIO ENTRE 10 Y 25 NM APROXIMADAMENTE.
ES93922479T 1992-10-08 1993-10-08 Composicion de agentes antineoplasticos incorporados en micelas. Expired - Lifetime ES2153387T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US95799892A 1992-10-08 1992-10-08

Publications (1)

Publication Number Publication Date
ES2153387T3 true ES2153387T3 (es) 2001-03-01

Family

ID=25500471

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93922479T Expired - Lifetime ES2153387T3 (es) 1992-10-08 1993-10-08 Composicion de agentes antineoplasticos incorporados en micelas.

Country Status (12)

Country Link
US (1) US5698529A (es)
EP (1) EP0619730B1 (es)
JP (1) JPH08506319A (es)
AT (1) ATE198268T1 (es)
AU (1) AU5147193A (es)
CA (1) CA2125500C (es)
DE (1) DE69329792T2 (es)
DK (1) DK0619730T3 (es)
ES (1) ES2153387T3 (es)
GR (1) GR3035125T3 (es)
PT (1) PT619730E (es)
WO (1) WO1994008564A1 (es)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6153193A (en) * 1993-04-28 2000-11-28 Supratek Pharma Inc. Compositions for targeting biological agents
US6093391A (en) * 1992-10-08 2000-07-25 Supratek Pharma, Inc. Peptide copolymer compositions
US6277410B1 (en) 1992-10-08 2001-08-21 Supratek Pharma Inc. Copolymer compositions for oral delivery
US5817321A (en) * 1992-10-08 1998-10-06 Supratek Pharma, Inc. Biological agent compositions
US6359054B1 (en) 1994-11-18 2002-03-19 Supratek Pharma Inc. Polynucleotide compositions for intramuscular administration
US6353055B1 (en) 1994-11-18 2002-03-05 Supratek Pharma Inc. Polynucleotide compositions
US6221959B1 (en) 1994-11-18 2001-04-24 Supratek Pharma, Inc. Polynucleotide compositions
US6060518A (en) * 1996-08-16 2000-05-09 Supratek Pharma Inc. Polymer compositions for chemotherapy and methods of treatment using the same
US20050003008A1 (en) * 1997-09-23 2005-01-06 Natalya Rapoport Method of in vivo drug targeting to solid tumors via acoustically triggered drug delivery in polymeric micelles
IL141438A0 (en) * 2000-02-23 2002-03-10 Pfizer Prod Inc Method of increasing the bioavailability and tissue penetration of azithromycin
US7291713B2 (en) * 2001-01-30 2007-11-06 Kyowa Hakko Kogyo Co., Ltd. Branched polyalkylene glycols
US20040253315A1 (en) * 2001-07-13 2004-12-16 Yasuaki Ogawa Lyophilizing composition of drug-encapsulating polymer micelle and method for preparation thereof
DE60234057D1 (de) 2001-07-25 2009-11-26 Raptor Pharmaceutical Inc Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke
US20040155861A1 (en) * 2002-05-30 2004-08-12 Jackson Iii Robert P. Portable display monitor
DK1889198T3 (da) 2005-04-28 2015-02-09 Proteus Digital Health Inc Farma-informatiksystem
EP1954242A4 (en) * 2005-11-30 2012-08-01 Generex Pharm Inc ORALLY ABSORPTED PHARMACEUTICAL FORMULATION AND METHOD OF ADMINISTRATION
US8795627B2 (en) 2007-03-21 2014-08-05 Raptor Pharmaceuticals Inc. Treatment of liver disorders by administration of RAP conjugates
CA2717958A1 (en) * 2008-03-17 2009-09-24 University Of Utah Research Foundation Dithiocarbamate metal chelates and methods of making and using thereof
ES2728225T3 (es) 2009-02-20 2019-10-23 2 Bbb Medicines B V Sistema de administración de fármacos a base de glutatión
EP2427178B1 (en) 2009-05-06 2023-01-04 Laboratory Skin Care, Inc. Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
KR20140032361A (ko) * 2011-01-31 2014-03-14 마루호 코 엘티디 고분자 역 미셀을 포함하는 피부용 조성물 및 그 제조방법
WO2023220641A2 (en) 2022-05-11 2023-11-16 Juno Therapeutics, Inc. Methods and uses related to t cell therapy and production of same

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4888220A (es) * 1972-03-04 1973-11-19
JPH0623095B2 (ja) * 1983-03-03 1994-03-30 森下ルセル株式会社 制癌剤を含有するエマルジヨン製剤
IE58981B1 (en) * 1985-10-15 1993-12-15 Vestar Inc Anthracycline antineoplastic agents encapsulated in phospholipid micellular particles
US5039527A (en) * 1989-02-24 1991-08-13 Medicontrol Corporation Hexamethylmelamine containing parenteral emulsions
JP2517760B2 (ja) * 1989-05-11 1996-07-24 新技術事業団 水溶性高分子化医薬製剤

Also Published As

Publication number Publication date
US5698529A (en) 1997-12-16
DK0619730T3 (da) 2001-01-29
CA2125500A1 (en) 1994-04-28
EP0619730A1 (en) 1994-10-19
CA2125500C (en) 2002-02-12
ATE198268T1 (de) 2001-01-15
WO1994008564A1 (en) 1994-04-28
DE69329792T2 (de) 2001-05-31
PT619730E (pt) 2001-04-30
DE69329792D1 (de) 2001-02-01
EP0619730B1 (en) 2000-12-27
JPH08506319A (ja) 1996-07-09
GR3035125T3 (en) 2001-03-30
AU5147193A (en) 1994-05-09

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