ES2150913T3 - Enantiomeros de derivados de ciclopenteno. - Google Patents

Enantiomeros de derivados de ciclopenteno.

Info

Publication number
ES2150913T3
ES2150913T3 ES92908235T ES92908235T ES2150913T3 ES 2150913 T3 ES2150913 T3 ES 2150913T3 ES 92908235 T ES92908235 T ES 92908235T ES 92908235 T ES92908235 T ES 92908235T ES 2150913 T3 ES2150913 T3 ES 2150913T3
Authority
ES
Spain
Prior art keywords
pct
image
iia
enantiomers
iib
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92908235T
Other languages
English (en)
Inventor
Christopher Thomas Evans
Stanley Michael Roberts
Karoline Shoberu
Rosemary Mackeith
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chirotech Technology Ltd
Original Assignee
Chirotech Technology Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chirotech Technology Ltd filed Critical Chirotech Technology Ltd
Application granted granted Critical
Publication of ES2150913T3 publication Critical patent/ES2150913T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C35/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C07C35/02—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring monocyclic
    • C07C35/06—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring monocyclic containing a five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/013—Esters of alcohols having the esterified hydroxy group bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/04—Oxygen as only ring hetero atoms containing a five-membered hetero ring, e.g. griseofulvin, vitamin C
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
    • C12P41/004—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of alcohol- or thiol groups in the enantiomers or the inverse reaction
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/874—Pseudomonas
    • Y10S435/876—Pseudomonas fluorescens

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)

Abstract

LOS ENANTIOMEROS INDIVIDUALES DE LOS COMPUESTOS (IA), (IB),(IIA) O (IIB), OPCIONALMENTE SUSTITUIDOS POR SUSTITUYENTE(S) NOINTERFERENTES. LOS NUEVOS ENANTIOMEROS PUEDEN SER OBTENIDOS POR BIOTRANSFORMACION. LOS COMPUESTOS (IA) O (IIA) PUEDEN SER USADOS POR LA SINTESIS DE NUCLEOSIDOS CARBOCICLICOS QUIRALES.
ES92908235T 1991-04-19 1992-04-21 Enantiomeros de derivados de ciclopenteno. Expired - Lifetime ES2150913T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB919108376A GB9108376D0 (en) 1991-04-19 1991-04-19 Cyclopentenes

Publications (1)

Publication Number Publication Date
ES2150913T3 true ES2150913T3 (es) 2000-12-16

Family

ID=10693560

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92908235T Expired - Lifetime ES2150913T3 (es) 1991-04-19 1992-04-21 Enantiomeros de derivados de ciclopenteno.

Country Status (8)

Country Link
US (1) US5714351A (es)
EP (1) EP0580667B1 (es)
AT (1) ATE196508T1 (es)
AU (1) AU1548592A (es)
DE (1) DE69231466T2 (es)
ES (1) ES2150913T3 (es)
GB (1) GB9108376D0 (es)
WO (1) WO1992018444A2 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9108376D0 (en) * 1991-04-19 1991-06-05 Enzymatix Ltd Cyclopentenes
US5840923A (en) * 1992-04-21 1998-11-24 Chiroscience Limited Chiral cyclopentene derivatives and their preparation
AU3961493A (en) * 1992-04-21 1993-11-18 Chiroscience Limited Chiral cyclopentene derivatives and their preparation
JPH07147994A (ja) * 1993-11-26 1995-06-13 Kureha Chem Ind Co Ltd １，２−ジオール誘導体の光学分割
SK285795B6 (sk) * 1998-12-23 2007-08-02 Lonza Ag Spôsob výroby enantiomérne obohatených derivátov 1-amino-4-(hydroxymetyl)-cyklopent-2-énu
DE50002340D1 (de) 1999-01-06 2003-07-03 Lonza Ag Verfahren zur herstellung von robenidin bzw. dessen derivate
ATE252541T1 (de) * 1999-04-27 2003-11-15 Firmenich & Cie Verfahren zum herstellen von chiralen epoxyden
US8236853B1 (en) 2007-12-03 2012-08-07 University Of South Florida Formation of cyclopentene nitro-ester and derivatives
JP2009232735A (ja) * 2008-03-26 2009-10-15 Tadakatsu Bandai （１ｒ，２ｒ）−１−アシロキシ−３−シクロアルケン又は（１ｓ，２ｓ）−３−シクロアルケン−１−オールの製造方法

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3965118A (en) * 1972-07-21 1976-06-22 The Upjohn Company Lactone intermediates
US4170596A (en) * 1976-10-05 1979-10-09 Kowa Company, Ltd. Novel monoesters of cis-cyclopentenediol, process for preparation thereof, and process for preparation of lactones from the monoesters
US4217284A (en) * 1976-10-05 1980-08-12 Kowa Company Ltd. Process for preparation of optically pure lactones from monoesters of cis-cyclopentenediol
DE3474546D1 (en) * 1983-02-03 1988-11-17 Sumitomo Chemical Co Optically active 4-hydroxy-2-cyclopentenones, and their production
US4607013A (en) * 1983-03-18 1986-08-19 Sumitomo Chemical Company, Limited Biochemical process for optical resolution of cyclopentenolone derivatives
DE3465185D1 (en) * 1983-05-25 1987-09-10 Sumitomo Chemical Co Process for producing optically active cyclopentenolones
DE3439598A1 (de) * 1984-06-01 1985-12-05 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von (1s, 4r)-4-hydroxy-2-cyclopentenylestern
PT83201A (en) * 1985-08-16 1986-09-01 Glaxo Group Ltd Guanine derivatives
DE3638762A1 (de) * 1986-11-13 1988-05-26 Schering Ag Racematspaltung von 7(alpha)-acyloxy-6ss-hydroxy-methyl-2-oxabicyclo (3.3.0)octan-3-onen durch stereospezifische enzymatische acylat-hydrolyse
IL84414A0 (en) * 1986-11-14 1988-04-29 Ciba Geigy Ag N9-cyclopentyl-substituted adenine derivatives
DE3724721A1 (de) * 1987-07-25 1989-04-13 Hoechst Ag Verfahren zur enzymatischen racematspaltung von 1-acyloxy-2-cyclopenten-4-on(2,2- dimethylpropandiol)-ketal
DE3743824C2 (de) * 1987-12-23 1997-03-06 Hoechst Ag Verfahren zur enzymatischen Racematspaltung von racemischen Alkoholen mit/in Vinylestern durch Umesterung
US4950758A (en) * 1988-01-20 1990-08-21 Regents Of The University Of Minnesota Optically-active isomers of dideoxycarbocyclic nucleosides
BE1003815A4 (fr) * 1988-01-20 1992-06-23 Univ Minnesota Nucleosides dideoxydidehydrocarbocyliques et composition pharmaceutique les contenant.
US4916224A (en) * 1988-01-20 1990-04-10 Regents Of The University Of Minnesota Dideoxycarbocyclic nucleosides
LU87593A1 (de) * 1989-09-25 1991-05-07 Europ Communities Enantioselektive enzymatische synthese von s(-)-und r(+)-estern des 4-hydroxy-cyclopenten-1-ons und seines 2',2'-dimethylpropan-1',3'-diol-ketals
MY104575A (en) * 1989-12-22 1994-04-30 The Wellcome Foundation Ltd Therapeutic nucleosides.
US5057630A (en) * 1990-04-06 1991-10-15 Glaxo Inc. Synthesis of cyclopentene derivatives
JP3097145B2 (ja) * 1991-02-27 2000-10-10 日産化学工業株式会社 コーリーラクトンジオールの光学分割方法
GB9108376D0 (en) * 1991-04-19 1991-06-05 Enzymatix Ltd Cyclopentenes

Also Published As

Publication number Publication date
GB9108376D0 (en) 1991-06-05
WO1992018444A3 (en) 1993-03-04
AU1548592A (en) 1992-11-17
DE69231466D1 (de) 2000-10-26
DE69231466T2 (de) 2001-01-25
EP0580667B1 (en) 2000-09-20
US5714351A (en) 1998-02-03
WO1992018444A2 (en) 1992-10-29
EP0580667A1 (en) 1994-02-02
ATE196508T1 (de) 2000-10-15

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