ES2149258T3 - Oligopeptidos de crecimiento osteogenico y composiciones farmaceuticas que los contienen. - Google Patents

Oligopeptidos de crecimiento osteogenico y composiciones farmaceuticas que los contienen.

Info

Publication number
ES2149258T3
ES2149258T3 ES94908419T ES94908419T ES2149258T3 ES 2149258 T3 ES2149258 T3 ES 2149258T3 ES 94908419 T ES94908419 T ES 94908419T ES 94908419 T ES94908419 T ES 94908419T ES 2149258 T3 ES2149258 T3 ES 2149258T3
Authority
ES
Spain
Prior art keywords
pharmaceutical compositions
gly
oligopeptides
contain
icautes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94908419T
Other languages
English (en)
Inventor
Itai Bab
Andras Muhlrad
Michael Chorev
Arie Shteyer
Zvi Greenberg
Nura Mansur
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yissum Research Development Co of Hebrew University of Jerusalem
Original Assignee
Yissum Research Development Co of Hebrew University of Jerusalem
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yissum Research Development Co of Hebrew University of Jerusalem filed Critical Yissum Research Development Co of Hebrew University of Jerusalem
Application granted granted Critical
Publication of ES2149258T3 publication Critical patent/ES2149258T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/51—Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Materials For Medical Uses (AREA)

Abstract

EL ELEMENTOS SE REFIERE A OLIGOPEPTIDOS BIOQUIMICAMENTE PUROS QUE TIENEN UNA ACTIVIDAD ESTIMULANTE SOBRE CELULAS FIBROBLASTICOS Y/O OSTEOBLASTICAS QUE TIENEN UN PESO MOLECULAR ENTRE 200 Y 2000. LOS OLIGOPEPTIDOS PREFERIDOS DE ACUERDO CON LA INVENCION COMPRENDEN SECUENCIAS DE AMINOACIDO TYR-GLY-PHE-HIS-GLY Y GLYPHE-GLY-GLY. LA INVENCION SE REFIERE ADEMAS A COMPOSICIONES FARMACEUTICAS PARA LA ESTIMULACION DE FOMRACION DE CELULAS FIBROBLASTICAS U OSTEOBLASTICAS, FORMACIONES DE HUESO REFORZADAS EN CONDICIONES PATOLOGICAS OSTEOGENICAS, REPARAMIENTO DE FRACTURAS, CICATRIZACION DE HERIDAS, IMPLANTES INTRAOSEOS Y SUPLEMENTACIONES DE HUESO, U OTRAS CONDICIONES QUE REQUIERAN CELULAS DE FORMACION OSEA REFORZADA CON UNA CANTIDAD TERAPEUTICAMENTE EFECTIVA DE UN OLIGOPEPTIDO DE ACUERDO CON LA INVENCION.
ES94908419T 1993-03-04 1994-03-04 Oligopeptidos de crecimiento osteogenico y composiciones farmaceuticas que los contienen. Expired - Lifetime ES2149258T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL104954A IL104954A (en) 1993-03-04 1993-03-04 Use of osteogenic oligopeptides in the preparation of pharmaceutical compositions for the treatment of bone diseases and some such novel oligopeptides, pharmaceutical compositions containing them and their preparation

Publications (1)

Publication Number Publication Date
ES2149258T3 true ES2149258T3 (es) 2000-11-01

Family

ID=11064593

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94908419T Expired - Lifetime ES2149258T3 (es) 1993-03-04 1994-03-04 Oligopeptidos de crecimiento osteogenico y composiciones farmaceuticas que los contienen.

Country Status (13)

Country Link
US (1) US5814610A (es)
EP (1) EP0687270B1 (es)
JP (1) JP3621099B2 (es)
AT (1) ATE193305T1 (es)
AU (1) AU6146794A (es)
CA (1) CA2157506C (es)
DE (1) DE69424657T2 (es)
DK (1) DK0687270T3 (es)
ES (1) ES2149258T3 (es)
GR (1) GR3034218T3 (es)
IL (1) IL104954A (es)
PT (1) PT687270E (es)
WO (1) WO1994020529A1 (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL117426A (en) * 1996-03-10 2005-09-25 Yissum Res Dev Co Synthetic pseudopeptides having osteogenic activity and pharmaceutical compositions containing the same
DE19906096A1 (de) 1999-02-13 2000-08-17 Walter Sebald Protein mit einem Heparin-bindenden Epitop
US20060078847A1 (en) * 2000-09-29 2006-04-13 Kwan Norman H Dental implant system and additional methods of attachment
CA2456092A1 (en) * 2001-07-29 2003-02-13 Yissum Research Development Company Of The Hebrew University In Jerusalem Osteogenic growth oligopeptides as stimulants of hematopoiesis
CN1189209C (zh) * 2001-11-23 2005-02-16 上海益众生物技术有限公司 成骨生长肽在促进造血方面的应用
CN1240436C (zh) * 2002-08-28 2006-02-08 上海益众生物技术有限公司 成骨生长肽与粒细胞集落刺激因子在造血方面的协同作用
CN101472944B (zh) 2006-06-13 2014-05-28 赫里克斯生物医疗公司 用于诱导细胞外基质蛋白合成的肽片段
CN103665109B (zh) * 2013-11-15 2016-01-20 陕西东大生化科技有限责任公司 成骨生长肽碳端五肽的合成方法
US10086035B2 (en) 2016-02-04 2018-10-02 ALASTIN Skincare, Inc. Compositions and methods for invasive and non-invasive procedural skincare
US10493011B2 (en) 2017-08-03 2019-12-03 ALASTIN Skincare, Inc. Peptide compositions and methods for ameliorating skin laxity and body contour
US11103455B2 (en) 2018-08-02 2021-08-31 ALASTIN Skincare, Inc. Liposomal compositions and methods of use

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4455256A (en) * 1981-05-05 1984-06-19 The Regents Of The University Of California Bone morphogenetic protein
US4434094A (en) * 1983-04-12 1984-02-28 Collagen Corporation Partially purified osteogenic factor and process for preparing same from demineralized bone
CA1282725C (en) * 1986-04-18 1991-04-09 Brian A. Naughton Process for replicating bone marrow in vitro and using the same
IL90683A0 (en) * 1988-06-27 1990-01-18 Yissum Res Dev Co Osteogenic growth factors derived from regenerating bone marrow
EP0384731B1 (en) * 1989-02-23 1996-12-18 Yissum Research Development Company Of The Hebrew University Of Jerusalem Osteogenic growth polypeptides identified from regenerating bone marrow
IL101747A0 (en) * 1992-04-30 1992-12-30 Yissum Res Dev Co C-terminal modified osteogenic growth polypeptides

Also Published As

Publication number Publication date
GR3034218T3 (en) 2000-12-29
DK0687270T3 (da) 2000-10-30
DE69424657T2 (de) 2001-02-08
IL104954A0 (en) 1993-07-08
EP0687270A1 (en) 1995-12-20
US5814610A (en) 1998-09-29
JP3621099B2 (ja) 2005-02-16
DE69424657D1 (de) 2000-06-29
IL104954A (en) 2006-08-01
WO1994020529A1 (en) 1994-09-15
JPH08509960A (ja) 1996-10-22
PT687270E (pt) 2000-11-30
ATE193305T1 (de) 2000-06-15
CA2157506A1 (en) 1994-09-15
AU6146794A (en) 1994-09-26
EP0687270B1 (en) 2000-05-24
CA2157506C (en) 2007-12-04

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