ES2148240T3 - Sintesis de derivados del acido n-acetil neuraminico. - Google Patents

Sintesis de derivados del acido n-acetil neuraminico.

Info

Publication number
ES2148240T3
ES2148240T3 ES93921839T ES93921839T ES2148240T3 ES 2148240 T3 ES2148240 T3 ES 2148240T3 ES 93921839 T ES93921839 T ES 93921839T ES 93921839 T ES93921839 T ES 93921839T ES 2148240 T3 ES2148240 T3 ES 2148240T3
Authority
ES
Spain
Prior art keywords
synthesis
derivatives
neuraminic acid
acetyl neuraminic
tetradeoxi
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93921839T
Other languages
English (en)
Inventor
Niall Galbraith Weir
Malcolm Chandler
Mark James Bamford
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biota Scientific Management Pty Ltd
Original Assignee
Biota Scientific Management Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biota Scientific Management Pty Ltd filed Critical Biota Scientific Management Pty Ltd
Application granted granted Critical
Publication of ES2148240T3 publication Critical patent/ES2148240T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Glass Compositions (AREA)
  • Iron Core Of Rotating Electric Machines (AREA)

Abstract

SE DESCRIBE UN METODO PARA LA PREPARACION DEL ACIDO 5-ACETAMIDO2,3,4,5-TETRADEOXI-4-GUANIDINO-D-GLICERO-D-GALACTO-NON-2-ENOPIRANOSONICO QUE COMPRENDE LA AMINACION DEL ACIDO 5-ACETAMIDO-4CIANOAMIDA-2,3,4,5-TETRADEOXI-D-GLICERO-D-GALACTO-NON-2-ENOPIRANOSONICO.
ES93921839T 1992-09-25 1993-09-23 Sintesis de derivados del acido n-acetil neuraminico. Expired - Lifetime ES2148240T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB929220241A GB9220241D0 (en) 1992-09-25 1992-09-25 Process

Publications (1)

Publication Number Publication Date
ES2148240T3 true ES2148240T3 (es) 2000-10-16

Family

ID=10722474

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93921839T Expired - Lifetime ES2148240T3 (es) 1992-09-25 1993-09-23 Sintesis de derivados del acido n-acetil neuraminico.

Country Status (14)

Country Link
EP (1) EP0662966B1 (es)
AT (1) ATE193287T1 (es)
AU (1) AU5108793A (es)
DE (1) DE69328728T2 (es)
DK (1) DK0662966T3 (es)
ES (1) ES2148240T3 (es)
FI (1) FI112225B (es)
GB (1) GB9220241D0 (es)
GR (1) GR3034138T3 (es)
HU (1) HU218423B (es)
NO (1) NO308661B1 (es)
PL (1) PL179578B1 (es)
PT (1) PT662966E (es)
WO (1) WO1994007885A1 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2081068C (en) * 1991-10-23 2005-11-29 Laurence Mark Von Itzstein Antiviral 4-substituted-2-deoxy-2,3-didehydro-derivatives of .alpha.-d-neuraminic acid
CN100409844C (zh) * 1995-02-27 2008-08-13 吉里德科学公司 神经氨酸苷酶抑制剂
US5866601A (en) * 1995-02-27 1999-02-02 Gilead Sciences, Inc. Carbocyclic compounds
US5763483A (en) * 1995-12-29 1998-06-09 Gilead Sciences, Inc. Carbocyclic compounds
US5859284A (en) * 1996-08-23 1999-01-12 Gilead Sciences, Inc. Preparation of carbocyclic compounds
US6518438B2 (en) 1996-08-23 2003-02-11 Gilead Sciences, Inc. Preparation of cyclohexene carboxylate derivatives
US5994377A (en) 1996-10-21 1999-11-30 Gilead Sciences, Inc. Piperidine compounds
US5886213A (en) * 1997-08-22 1999-03-23 Gilead Sciences, Inc. Preparation of carbocyclic compounds
TW480247B (en) * 1997-12-12 2002-03-21 Gilead Sciences Inc Novel compounds useful as neuraminidase inhibitors and pharmaceutical compositions containing same
EP2358695B1 (en) * 2008-11-28 2014-07-02 Cipla Limited Process for preparing zanamivir and intermediates for use in the process
WO2012114350A1 (en) 2011-02-24 2012-08-30 Cadila Healthcare Limited Process for the preparation of zanamivir
DE102011117128A1 (de) * 2011-10-28 2013-05-02 Christian-Albrechts-Universität Zu Kiel Verbindungen zur Therapie der Influenza

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK282950B6 (sk) * 1990-04-24 2003-01-09 Biota Scientific Management Pty Ltd Deriváty alfa-D-neuramínovej kyseliny, spôsob ich prípravy, ich použitie a farmaceutické prípravky na ich báze
CA2081068C (en) * 1991-10-23 2005-11-29 Laurence Mark Von Itzstein Antiviral 4-substituted-2-deoxy-2,3-didehydro-derivatives of .alpha.-d-neuraminic acid
GB9126725D0 (en) * 1991-12-17 1992-02-12 Glaxo Group Ltd Process

Also Published As

Publication number Publication date
FI951377L (fi) 1995-03-23
NO951135L (no) 1995-05-08
DE69328728T2 (de) 2000-12-28
PL179578B1 (pl) 2000-09-29
WO1994007885A1 (en) 1994-04-14
PL308202A1 (en) 1995-07-24
ATE193287T1 (de) 2000-06-15
HU218423B (hu) 2000-08-28
FI112225B (fi) 2003-11-14
DE69328728D1 (de) 2000-06-29
FI951377A0 (fi) 1995-03-23
NO308661B1 (no) 2000-10-09
PT662966E (pt) 2000-09-29
HUT72030A (en) 1996-03-28
HU9500867D0 (en) 1995-05-29
GR3034138T3 (en) 2000-11-30
AU5108793A (en) 1994-04-26
HK1014184A1 (en) 1999-09-24
EP0662966B1 (en) 2000-05-24
EP0662966A1 (en) 1995-07-19
NO951135D0 (no) 1995-03-24
GB9220241D0 (en) 1992-11-11
DK0662966T3 (da) 2000-08-07

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