ES2145292T3 - Procedimiento bacteriano para la resolucion de cis-dioles racemicos. - Google Patents
Procedimiento bacteriano para la resolucion de cis-dioles racemicos.Info
- Publication number
- ES2145292T3 ES2145292T3 ES95930597T ES95930597T ES2145292T3 ES 2145292 T3 ES2145292 T3 ES 2145292T3 ES 95930597 T ES95930597 T ES 95930597T ES 95930597 T ES95930597 T ES 95930597T ES 2145292 T3 ES2145292 T3 ES 2145292T3
- Authority
- ES
- Spain
- Prior art keywords
- resolution
- diols
- bacterial
- procedure
- racemic cis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000000034 method Methods 0.000 title abstract 2
- 230000001580 bacterial effect Effects 0.000 title 1
- QUUSLJRWTDZCBF-UHFFFAOYSA-N 2,3-dihydroindene-1,1-diol Chemical class C1=CC=C2C(O)(O)CCC2=C1 QUUSLJRWTDZCBF-UHFFFAOYSA-N 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
- 241000589776 Pseudomonas putida Species 0.000 abstract 1
- 239000003905 agrochemical Substances 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C12P41/002—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by oxidation/reduction reactions
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/582—Recycling of unreacted starting or intermediate materials
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/874—Pseudomonas
- Y10S435/877—Pseudomonas putida
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Steroid Compounds (AREA)
- Glass Compositions (AREA)
- Iron Core Of Rotating Electric Machines (AREA)
Abstract
UN PROCEDIMIENTO PARA RESOLUCION DE UNA MEZCLA DE ENANTIOMEROS DE DIHIDROXIDIHIDROINDENO QUE COMPRENDE EL TRATAMIENTO DE LA MEZCLA DE ENANTIOMEROS CON UN MICROORGANISMOS DE ESPECIE PSEUDOMONAS PUTIDA. LOS DIHIDROXIDIHIDROINDENOS RESUELTOS SON VALIOSOS INTERMEDIARIOS PARA LA SINTESIS DE COMPUESTOS BIOLOGICAMENTE ACTIVOS COMO PRODUCTOS FARMACEUTICOS Y AGROQUIMICOS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9420067A GB9420067D0 (en) | 1994-10-05 | 1994-10-05 | Process |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2145292T3 true ES2145292T3 (es) | 2000-07-01 |
Family
ID=10762372
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES95930597T Expired - Lifetime ES2145292T3 (es) | 1994-10-05 | 1995-08-31 | Procedimiento bacteriano para la resolucion de cis-dioles racemicos. |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US5811294A (es) |
| EP (1) | EP0784697B1 (es) |
| JP (1) | JP3917653B2 (es) |
| AT (1) | ATE192501T1 (es) |
| CA (1) | CA2199159A1 (es) |
| DE (1) | DE69516705T2 (es) |
| ES (1) | ES2145292T3 (es) |
| GB (1) | GB9420067D0 (es) |
| WO (1) | WO1996011282A1 (es) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9420067D0 (en) * | 1994-10-05 | 1994-11-16 | Zeneca Ltd | Process |
| US5858737A (en) * | 1995-06-20 | 1999-01-12 | Merck & Co., Inc. | Conversion of indene to (1S)-amino-(2R)-indanol free of any stereoisomer, by combination of dioxygenase bioconversion and chemical steps |
| US5824540A (en) * | 1995-06-20 | 1998-10-20 | Merck & Co., Inc. | Pseudomonas putida strain with dioxygenase activity |
| BR9608804A (pt) * | 1995-06-20 | 1999-02-17 | Merck & Co Inc | Processos para sintetizar (1s,2r) indandiol para sintetizar (1s) amino (2r) indanol substancialmente isento de qualquer estereoisômero de bio-resolução para remover cis (1s,2r) indandiol de uma mistura de cis (1s,2r) indandiol e cis (1r,2s) indandiol e cultura pura |
| EP0874059A4 (en) * | 1996-01-12 | 1999-10-27 | Nippon Steel Chemical Co | Processes for producing indane derivatives |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9420067D0 (en) * | 1994-10-05 | 1994-11-16 | Zeneca Ltd | Process |
| US5858737A (en) * | 1995-06-20 | 1999-01-12 | Merck & Co., Inc. | Conversion of indene to (1S)-amino-(2R)-indanol free of any stereoisomer, by combination of dioxygenase bioconversion and chemical steps |
| BR9608804A (pt) * | 1995-06-20 | 1999-02-17 | Merck & Co Inc | Processos para sintetizar (1s,2r) indandiol para sintetizar (1s) amino (2r) indanol substancialmente isento de qualquer estereoisômero de bio-resolução para remover cis (1s,2r) indandiol de uma mistura de cis (1s,2r) indandiol e cis (1r,2s) indandiol e cultura pura |
-
1994
- 1994-10-05 GB GB9420067A patent/GB9420067D0/en active Pending
-
1995
- 1995-08-31 WO PCT/GB1995/002051 patent/WO1996011282A1/en not_active Ceased
- 1995-08-31 CA CA002199159A patent/CA2199159A1/en not_active Abandoned
- 1995-08-31 AT AT95930597T patent/ATE192501T1/de not_active IP Right Cessation
- 1995-08-31 EP EP95930597A patent/EP0784697B1/en not_active Expired - Lifetime
- 1995-08-31 US US08/817,108 patent/US5811294A/en not_active Expired - Fee Related
- 1995-08-31 DE DE69516705T patent/DE69516705T2/de not_active Expired - Fee Related
- 1995-08-31 ES ES95930597T patent/ES2145292T3/es not_active Expired - Lifetime
- 1995-08-31 JP JP51239796A patent/JP3917653B2/ja not_active Expired - Fee Related
-
1998
- 1998-06-09 US US09/093,875 patent/US6165777A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US6165777A (en) | 2000-12-26 |
| US5811294A (en) | 1998-09-22 |
| JPH10506792A (ja) | 1998-07-07 |
| CA2199159A1 (en) | 1996-04-18 |
| DE69516705D1 (de) | 2000-06-08 |
| EP0784697A1 (en) | 1997-07-23 |
| ATE192501T1 (de) | 2000-05-15 |
| DE69516705T2 (de) | 2000-09-07 |
| JP3917653B2 (ja) | 2007-05-23 |
| WO1996011282A1 (en) | 1996-04-18 |
| GB9420067D0 (en) | 1994-11-16 |
| EP0784697B1 (en) | 2000-05-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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