ES2145113T3 - Dispositivo para la administracion vaginal de tamoxifeno o sus analogos. - Google Patents

Dispositivo para la administracion vaginal de tamoxifeno o sus analogos.

Info

Publication number
ES2145113T3
ES2145113T3 ES94402974T ES94402974T ES2145113T3 ES 2145113 T3 ES2145113 T3 ES 2145113T3 ES 94402974 T ES94402974 T ES 94402974T ES 94402974 T ES94402974 T ES 94402974T ES 2145113 T3 ES2145113 T3 ES 2145113T3
Authority
ES
Spain
Prior art keywords
tamoxifeno
analogs
alkyl
vaginal administration
pref
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94402974T
Other languages
English (en)
Inventor
Stephen Alan Matlin
Andrew Thomas Wilkins
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Aventis Pharmaceuticals Inc
Original Assignee
Hoechst Marion Roussel
Hoechst Marion Roussel Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel, Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel
Application granted granted Critical
Publication of ES2145113T3 publication Critical patent/ES2145113T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Reproductive Health (AREA)
  • Epidemiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Urology & Nephrology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

UN DISPOSITIVO MEDICO DESTINADO A SER INSERTADO EN UNA CAVIDAD QUE COMPRENDE UN ANILLO DE ELASTOMERO QUE CONTIENE UN COMPUESTO FARMACOLOGICAMENTE ACTIVO DE FORMULA (I) EN LA QUE R1 REPRESENTA EL HIDROGENO O UN RADICAL ALKILO QUE CONTIENEN DE 1 A 6 ATOMOS DE CARBONO; R2 REPRESENTA UN RADICAL ALKILO QUE CONTIENEN DE 1 A 6 ATOMOS DE CARBONO; N REPRESENTA UN NUMERO ENTERO DE 2 A 6, PREFERENTEMENTE 2; R3 Y R4 IDENTICOS O DIFERENTES REPRESENTAN CADA UNO RADICALES ARILO (C8-C12) QUE PUEDEN LLEVAR EVENTUALMENTE UNO O DOS SUSTITUYENTES ELEGIDOS ENTRE LOS ATOMOS DE HALOGENO, LOS RADICALES ALKILO (C1-C6) Y ALCOXI (C1-C6); Y R5 REPRESENTA UN RADICAL (C1-C6): O UNA SAL FARMACEUTICAMENTE ACEPTABLE DE ESTE, PUEDE VENTAJOSAMENTE UTILIZARSE PARA EL TRATAMIENTO Y LA PROFILAXIS DEL CANCER DE SENO.
ES94402974T 1993-12-23 1994-12-21 Dispositivo para la administracion vaginal de tamoxifeno o sus analogos. Expired - Lifetime ES2145113T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB939326255A GB9326255D0 (en) 1993-12-23 1993-12-23 Medical device for the prevention and treatment of cancer

Publications (1)

Publication Number Publication Date
ES2145113T3 true ES2145113T3 (es) 2000-07-01

Family

ID=10747070

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94402974T Expired - Lifetime ES2145113T3 (es) 1993-12-23 1994-12-21 Dispositivo para la administracion vaginal de tamoxifeno o sus analogos.

Country Status (10)

Country Link
US (1) US5558877A (es)
EP (1) EP0664120B1 (es)
JP (1) JPH07252142A (es)
AT (1) ATE192036T1 (es)
DE (1) DE69424147T2 (es)
DK (1) DK0664120T3 (es)
ES (1) ES2145113T3 (es)
GB (1) GB9326255D0 (es)
GR (1) GR3033571T3 (es)
PT (1) PT664120E (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0862445B2 (en) * 1995-10-06 2017-03-22 Arch Development Corporation Combination of herpes simplex virus and chemotherapy for treating cancer
DE69929055T2 (de) 1998-05-01 2006-07-20 Duramed Pharmaceuticals Inc., Cincinnati Verfahren zur spritzgussherstellung von vorrichtungen mit kontrollierter wirkstofffreisetzung und damit hergestellte vorrichtung
DE20020659U1 (de) 2000-12-06 2001-03-08 WIK Elektro-Hausgeräte Vertriebsgesellschaft mbH & Co. Produktions KG, 45355 Essen Schalteranordnung für ein elektrisches Handgerät
AU781168B2 (en) * 2001-01-26 2005-05-12 Pfizer Products Inc. Method of treating certain cancers using an estrogen agonist/antagonist
WO2002085327A2 (en) * 2001-04-18 2002-10-31 Oraltech Pharmaceuticals, Inc. Use of nsaids for prevention and treatment of cellular abnormalities of the female reproductive tract
EP1287817A1 (en) * 2001-08-31 2003-03-05 Pantarhei Bioscience B.V. Method of treating uterine leiomyomas and intravaginal drug delivery vehicle for use in such method
WO2003017973A1 (en) * 2001-08-31 2003-03-06 Pantarhei Bioscience B.V. A method of treating benign gynaecological disorders and a drug delivery vehicle for use in such a method
WO2007143607A2 (en) * 2006-06-02 2007-12-13 Pear Tree Women's Health Care Method of treating atrophic vaginitis
EP2094270A1 (en) * 2006-11-22 2009-09-02 N.V. Organon Delivery system for risperidone
WO2009064442A1 (en) 2007-11-13 2009-05-22 Brookwood Pharmaceuticals, Inc. Viscous terpolymers as drug delivery platform
WO2009142968A2 (en) * 2008-05-20 2009-11-26 Olema Pharmaceuticals, Inc. Valproic acid salts
WO2009143309A2 (en) * 2008-05-21 2009-11-26 Trustees Of Dartmouth College Female reproductive tract and anal prophylaxes
FI121000B (fi) * 2008-11-19 2010-06-15 Bayer Schering Pharma Oy Intravaginaalinen antojärjestelmä ja menetelmä sen valmistamiseksi
US8951546B2 (en) 2008-12-23 2015-02-10 Surmodics Pharmaceuticals, Inc. Flexible implantable composites and implants comprising same
US20100168807A1 (en) * 2008-12-23 2010-07-01 Burton Kevin W Bioactive terpolymer compositions and methods of making and using same
US9415197B2 (en) 2008-12-23 2016-08-16 Surmodics, Inc. Implantable suction cup composites and implants comprising same
US8974808B2 (en) * 2008-12-23 2015-03-10 Surmodics, Inc. Elastic implantable composites and implants comprising same
US8920921B2 (en) 2010-08-30 2014-12-30 Surmodics Pharmaceuticals, Inc. Terpolymer blends and their use as pressure-sensitive adhesives
US20120259160A1 (en) * 2011-04-11 2012-10-11 Nancy Karapasha Pessary device having improved comfort
WO2015198104A1 (es) * 2014-06-28 2015-12-30 Laboratorios Andromaco S.A. Pesario de cerclaje que contiene progesterona de liberación prolongada, sostenida y continua, útil para la prevención de parto prematuro

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE637389A (es) * 1962-09-13
US4235988A (en) * 1976-12-13 1980-11-25 Imperial Chemical Industries Limited Delivery means for biologically active agents
GB1551620A (en) * 1976-12-13 1979-08-30 Ici Ltd Delivery means for biologically active agents
DE3040978A1 (de) * 1980-10-28 1982-05-27 Schering Ag, 1000 Berlin Und 4619 Bergkamen Vaginalring
DE3925507A1 (de) * 1989-07-28 1991-01-31 Schering Ag 14,17(alpha)-etheno- und ethanoestratriene, verfahren zur herstellung dieser verbindungen, sowie ihre verwendung zur herstellung von arzneimitteln
WO1992018101A1 (en) * 1991-04-12 1992-10-29 The Upjohn Company Vaginal drug delivery device

Also Published As

Publication number Publication date
DK0664120T3 (da) 2000-09-18
ATE192036T1 (de) 2000-05-15
PT664120E (pt) 2000-08-31
US5558877A (en) 1996-09-24
GB9326255D0 (en) 1994-02-23
EP0664120B1 (fr) 2000-04-26
EP0664120A1 (fr) 1995-07-26
DE69424147D1 (de) 2000-05-31
JPH07252142A (ja) 1995-10-03
DE69424147T2 (de) 2000-12-14
GR3033571T3 (en) 2000-09-29

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