ES2144522T3 - Anticuerpos anti-ca125 anti-idiotipicos monoclonales y composiciones farmaceuticas que los contienen. - Google Patents

Anticuerpos anti-ca125 anti-idiotipicos monoclonales y composiciones farmaceuticas que los contienen.

Info

Publication number
ES2144522T3
ES2144522T3 ES94918798T ES94918798T ES2144522T3 ES 2144522 T3 ES2144522 T3 ES 2144522T3 ES 94918798 T ES94918798 T ES 94918798T ES 94918798 T ES94918798 T ES 94918798T ES 2144522 T3 ES2144522 T3 ES 2144522T3
Authority
ES
Spain
Prior art keywords
pct
pharmaceutical compositions
compositions containing
idiotipic
antibodies
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94918798T
Other languages
English (en)
Inventor
Uwe Dr Med Wagner
Harald Schlebusch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of ES2144522T3 publication Critical patent/ES2144522T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4208—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig
    • C07K16/4241—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig
    • C07K16/4258—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig against anti-receptor Ig
    • C07K16/4266—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig against anti-receptor Ig against anti-tumor receptor Ig
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57449—Specifically defined cancers of ovaries
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • G01N33/686—Anti-idiotype
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

SE PRESENTA UN ANTICUERPO ANTIIDIOTIPICO QUE REACCIONA CON UN ANTICUERPO ANTI- CA125 Y COMPITE CON UN CA125 EN SU ENLACE A DICHO ANTICUERPO ANTI-CA125. ADEMAS SE PRESENTAN FRAGMENTOS DE DICHO ANTICUERPO ANTIIDIOTIPICO QUE TIENEN ESENCIALMENTE LA MISMA ESPECIFICIDAD AL ENLACE. ADICIONALMENTE, LA INVENCION SE REFIERE A LINEAS CELULARES, EN PARTICULAR AL HIBRIDOMA 3D5 (DSM ACC2120), PARA LA PRODUCCION DE DICHOS ANTICUERPOS ANTIIDIOTIPICOS. TAMBIEN SE PRESENTAN COMPOSICIONES FARMACEUTICAS QUE CONTIENEN DICHOS ANTICUERPOS ANTIIDIOTIPICOS Y LOS USOS ESPECIFICOS DE ESTOS ANTICUERPOS.
ES94918798T 1993-05-27 1994-05-26 Anticuerpos anti-ca125 anti-idiotipicos monoclonales y composiciones farmaceuticas que los contienen. Expired - Lifetime ES2144522T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP93108583 1993-05-27

Publications (1)

Publication Number Publication Date
ES2144522T3 true ES2144522T3 (es) 2000-06-16

Family

ID=8212947

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94918798T Expired - Lifetime ES2144522T3 (es) 1993-05-27 1994-05-26 Anticuerpos anti-ca125 anti-idiotipicos monoclonales y composiciones farmaceuticas que los contienen.

Country Status (9)

Country Link
US (1) US5858361A (es)
EP (1) EP0700305B1 (es)
JP (1) JP3764165B2 (es)
AT (1) ATE189122T1 (es)
AU (1) AU6997394A (es)
CA (1) CA2163868C (es)
DE (1) DE69422809T2 (es)
ES (1) ES2144522T3 (es)
WO (1) WO1994027637A1 (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11507046A (ja) * 1995-06-07 1999-06-22 イムノメディクス，インコーポレイテッド 診断剤および治療剤の標的部位への改良された送達方法
US8038994B2 (en) 1996-05-15 2011-10-18 Quest Pharmatech Inc. Combination therapy for treating disease
NZ505174A (en) * 1996-05-15 2002-03-01 Altarex Inc Cancer antigens CA125 (multiple epitote) recognised by OC125, M11, B43.13, B27.1, where B43.13 is used as a binding agent to elicit host immune response as a vaccination method against cancer
GB2413960A (en) * 2001-03-21 2005-11-16 Altarex Inc Treating ovarian cancer
DE10296942T5 (de) * 2001-03-21 2004-11-18 Altarex Corp., Edmonton Therapeutische Zusammensetzung, welche die Immunitätsreaktion verändert
AT500649A1 (de) * 2001-10-26 2006-02-15 Altarex Medical Corp Kombinationstherapie zur krankheitsbehandlung
DE10210239A1 (de) * 2002-03-08 2003-09-25 Cellcontrol Biomedical Lab Ag Spezifische Ab1'-Antikörper gegen das Tumor-assoziierte Antigen CA125
EP2298806A1 (en) 2002-10-16 2011-03-23 Purdue Pharma L.P. Antibodies that bind cell-associated CA 125/0722P and methods of use thereof
US20090226367A1 (en) * 2005-03-11 2009-09-10 Euro-Celtique S.A. Compositions comprising an anti-ca125 antibody and a cytotoxic compound and their use for the treatment of cancer
ITFI20060163A1 (it) * 2006-06-29 2006-09-28 Menarini Internat Operations Luxembourg Sa Composizione farmaceutica contenente un anticorpo monoclonale anti idiotipico anti-ca-125 ed alluminio
US8969024B2 (en) 2007-08-28 2015-03-03 Abbvie Biotechnology Ltd Compositions and methods comprising binding proteins for adalimumab

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01224399A (ja) * 1988-03-02 1989-09-07 Sumitomo Electric Ind Ltd 抗イディオタイプ抗体
JP3095169B2 (ja) * 1988-10-17 2000-10-03 キャンサー リサーチ キャンペーン テクノロジー リミティド 抗イディオタイプ抗体による抗腫瘍応答の誘導

Also Published As

Publication number Publication date
EP0700305B1 (en) 2000-01-26
CA2163868C (en) 2008-01-08
EP0700305A1 (en) 1996-03-13
AU6997394A (en) 1994-12-20
US5858361A (en) 1999-01-12
JPH08510460A (ja) 1996-11-05
DE69422809T2 (de) 2000-10-12
DE69422809D1 (de) 2000-03-02
JP3764165B2 (ja) 2006-04-05
ATE189122T1 (de) 2000-02-15
CA2163868A1 (en) 1994-12-08
WO1994027637A1 (en) 1994-12-08

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