ES2143940B1 - SELECTIVE PREPARATION PROCEDURE OF ALPHA-HYDROXIACID DERIVATIVES. - Google Patents

SELECTIVE PREPARATION PROCEDURE OF ALPHA-HYDROXIACID DERIVATIVES.

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Publication number
ES2143940B1
ES2143940B1 ES9800415A ES9800415A ES2143940B1 ES 2143940 B1 ES2143940 B1 ES 2143940B1 ES 9800415 A ES9800415 A ES 9800415A ES 9800415 A ES9800415 A ES 9800415A ES 2143940 B1 ES2143940 B1 ES 2143940B1
Authority
ES
Spain
Prior art keywords
derivatives
preparation procedure
selective preparation
hydroxiacid
alpha
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
ES9800415A
Other languages
Spanish (es)
Other versions
ES2143940A1 (en
Inventor
Bolanos Guzman Juan Fernandez
Moreno Antonia Heredia
Becerra Blanca Felizon
Bejarano Rafael Guillen
Araujo Ana Jimenez
Arcos Rocio Rodriguez
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Consejo Superior de Investigaciones Cientificas CSIC
Original Assignee
Consejo Superior de Investigaciones Cientificas CSIC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Consejo Superior de Investigaciones Cientificas CSIC filed Critical Consejo Superior de Investigaciones Cientificas CSIC
Priority to ES9800415A priority Critical patent/ES2143940B1/en
Publication of ES2143940A1 publication Critical patent/ES2143940A1/en
Application granted granted Critical
Publication of ES2143940B1 publication Critical patent/ES2143940B1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Procedimiento de preparación selectiva de derivados de {a -hidroxiácidos. Se basa en la simple mezcla del {a -hidroxiácido con alcoholes o ácidos grasos, la adición de disolvente y enzima. La utilización de lipasas permite obtener de forma regioselectiva y sin catalizadores ni agentes tóxicos, ésteres de hidroxiácidos en forma exclusivamente monomérica. Resulta de gran importancia el control del contenido en agua del medio. Los productos obtenidos son utilizados bien como emulgentes, humectantes y en distintas formulaciones cosméticas y farmacéuticas.Selective preparation procedure for derivatives of {a-hydroxy acids. It is based on the simple mixture of {a -hydroxy acid with alcohols or fatty acids, the addition of solvent and enzyme. The use of lipases allows to obtain regioselectively and without catalysts or toxic agents, hydroxy acid esters in an exclusively monomeric manner. Control of the water content of the medium is of great importance. The products obtained are used well as emulsifiers, humectants and in different cosmetic and pharmaceutical formulations.

ES9800415A 1998-02-26 1998-02-26 SELECTIVE PREPARATION PROCEDURE OF ALPHA-HYDROXIACID DERIVATIVES. Expired - Fee Related ES2143940B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES9800415A ES2143940B1 (en) 1998-02-26 1998-02-26 SELECTIVE PREPARATION PROCEDURE OF ALPHA-HYDROXIACID DERIVATIVES.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES9800415A ES2143940B1 (en) 1998-02-26 1998-02-26 SELECTIVE PREPARATION PROCEDURE OF ALPHA-HYDROXIACID DERIVATIVES.

Publications (2)

Publication Number Publication Date
ES2143940A1 ES2143940A1 (en) 2000-05-16
ES2143940B1 true ES2143940B1 (en) 2000-12-16

Family

ID=8302929

Family Applications (1)

Application Number Title Priority Date Filing Date
ES9800415A Expired - Fee Related ES2143940B1 (en) 1998-02-26 1998-02-26 SELECTIVE PREPARATION PROCEDURE OF ALPHA-HYDROXIACID DERIVATIVES.

Country Status (1)

Country Link
ES (1) ES2143940B1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7863025B2 (en) 2004-10-18 2011-01-04 Chemic Laboratories, Inc. Synthesis of fatty alcohol esters of alpha-hydroxy carboxylic acids and their use as percutaneous absorption enhancers

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2027649C (en) * 1989-10-20 1996-01-16 John Anthony Bosley Supported enzyme
EP0506159A1 (en) * 1991-03-19 1992-09-30 Unichema Chemie B.V. Esterification process
GB9225054D0 (en) * 1992-11-30 1993-01-20 Baxenden Chem Enzymatic synthesis

Also Published As

Publication number Publication date
ES2143940A1 (en) 2000-05-16

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