ES2143940B1 - SELECTIVE PREPARATION PROCEDURE OF ALPHA-HYDROXIACID DERIVATIVES. - Google Patents
SELECTIVE PREPARATION PROCEDURE OF ALPHA-HYDROXIACID DERIVATIVES.Info
- Publication number
- ES2143940B1 ES2143940B1 ES9800415A ES9800415A ES2143940B1 ES 2143940 B1 ES2143940 B1 ES 2143940B1 ES 9800415 A ES9800415 A ES 9800415A ES 9800415 A ES9800415 A ES 9800415A ES 2143940 B1 ES2143940 B1 ES 2143940B1
- Authority
- ES
- Spain
- Prior art keywords
- derivatives
- preparation procedure
- selective preparation
- hydroxiacid
- alpha
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Procedimiento de preparación selectiva de derivados de {a -hidroxiácidos. Se basa en la simple mezcla del {a -hidroxiácido con alcoholes o ácidos grasos, la adición de disolvente y enzima. La utilización de lipasas permite obtener de forma regioselectiva y sin catalizadores ni agentes tóxicos, ésteres de hidroxiácidos en forma exclusivamente monomérica. Resulta de gran importancia el control del contenido en agua del medio. Los productos obtenidos son utilizados bien como emulgentes, humectantes y en distintas formulaciones cosméticas y farmacéuticas.Selective preparation procedure for derivatives of {a-hydroxy acids. It is based on the simple mixture of {a -hydroxy acid with alcohols or fatty acids, the addition of solvent and enzyme. The use of lipases allows to obtain regioselectively and without catalysts or toxic agents, hydroxy acid esters in an exclusively monomeric manner. Control of the water content of the medium is of great importance. The products obtained are used well as emulsifiers, humectants and in different cosmetic and pharmaceutical formulations.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES9800415A ES2143940B1 (en) | 1998-02-26 | 1998-02-26 | SELECTIVE PREPARATION PROCEDURE OF ALPHA-HYDROXIACID DERIVATIVES. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES9800415A ES2143940B1 (en) | 1998-02-26 | 1998-02-26 | SELECTIVE PREPARATION PROCEDURE OF ALPHA-HYDROXIACID DERIVATIVES. |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2143940A1 ES2143940A1 (en) | 2000-05-16 |
ES2143940B1 true ES2143940B1 (en) | 2000-12-16 |
Family
ID=8302929
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES9800415A Expired - Fee Related ES2143940B1 (en) | 1998-02-26 | 1998-02-26 | SELECTIVE PREPARATION PROCEDURE OF ALPHA-HYDROXIACID DERIVATIVES. |
Country Status (1)
Country | Link |
---|---|
ES (1) | ES2143940B1 (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7863025B2 (en) | 2004-10-18 | 2011-01-04 | Chemic Laboratories, Inc. | Synthesis of fatty alcohol esters of alpha-hydroxy carboxylic acids and their use as percutaneous absorption enhancers |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2027649C (en) * | 1989-10-20 | 1996-01-16 | John Anthony Bosley | Supported enzyme |
EP0506159A1 (en) * | 1991-03-19 | 1992-09-30 | Unichema Chemie B.V. | Esterification process |
GB9225054D0 (en) * | 1992-11-30 | 1993-01-20 | Baxenden Chem | Enzymatic synthesis |
-
1998
- 1998-02-26 ES ES9800415A patent/ES2143940B1/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
ES2143940A1 (en) | 2000-05-16 |
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Legal Events
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