AR004093A1 - THE USE OF A PROTEIN DERIVED FROM A MAMMALIAN CHEMIOQUINE AND A USEFUL MEDICINAL PRODUCT TO MOBILIZE HEMATOPOIETIC STEM CELLS. - Google Patents
THE USE OF A PROTEIN DERIVED FROM A MAMMALIAN CHEMIOQUINE AND A USEFUL MEDICINAL PRODUCT TO MOBILIZE HEMATOPOIETIC STEM CELLS.Info
- Publication number
- AR004093A1 AR004093A1 ARP960104890A ARP960104890A AR004093A1 AR 004093 A1 AR004093 A1 AR 004093A1 AR P960104890 A ARP960104890 A AR P960104890A AR P960104890 A ARP960104890 A AR P960104890A AR 004093 A1 AR004093 A1 AR 004093A1
- Authority
- AR
- Argentina
- Prior art keywords
- stem cells
- mammalian
- protein derived
- chemioquine
- hematopoietic stem
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/521—Chemokines
- C07K14/522—Alpha-chemokines, e.g. NAP-2, ENA-78, GRO-alpha/MGSA/NAP-3, GRO-beta/MIP-2alpha, GRO-gamma/MIP-2beta, IP-10, GCP-2, MIG, PBSF, PF-4, KC
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/193—Colony stimulating factors [CSF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/49—Platelet-derived growth factor [PDGF]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Toxicology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Diabetes (AREA)
- General Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Se presenta el uso de una proteína derivada de una quimioquina de mamífero y el medicamento útil para movilizar células troncohematopoyéticas procedentes de la médula ósea hacia la circulación periférica mediante administración a unanima l de una cantidad eficaz de las formasmaduras, modificadas o multiméricas de KC, gro-beta, gro-alfa, ó gro-gamma.The use of a protein derived from a mammalian chemokine and the drug useful for mobilizing stem cells from the bone marrow into the peripheral circulation by administering to an animal an effective amount of the mature, modified or multimeric forms of KC, gro -beta, gro-alpha, or gro-gamma.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US54726295A | 1995-10-24 | 1995-10-24 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR004093A1 true AR004093A1 (en) | 1998-09-30 |
Family
ID=24183989
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP960104890A AR004093A1 (en) | 1995-10-24 | 1996-10-24 | THE USE OF A PROTEIN DERIVED FROM A MAMMALIAN CHEMIOQUINE AND A USEFUL MEDICINAL PRODUCT TO MOBILIZE HEMATOPOIETIC STEM CELLS. |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP0866806A4 (en) |
JP (1) | JPH11512747A (en) |
KR (1) | KR19990066997A (en) |
AR (1) | AR004093A1 (en) |
AU (1) | AU712235B2 (en) |
BR (1) | BR9611173A (en) |
CZ (1) | CZ120298A3 (en) |
HU (1) | HUP9802531A3 (en) |
NO (1) | NO981818L (en) |
NZ (1) | NZ321789A (en) |
PL (1) | PL326364A1 (en) |
TR (1) | TR199800742T2 (en) |
WO (1) | WO1997015595A1 (en) |
ZA (1) | ZA968896B (en) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6391589B1 (en) | 1994-08-23 | 2002-05-21 | Human Genome Sciences, Inc. | Human chemokine beta-10 mutant polypeptides |
US6174995B1 (en) | 1994-08-23 | 2001-01-16 | Haodong Li | Human chemokines, CKβ4 and CKβ10/MCP-4 |
US6458349B1 (en) | 1995-06-02 | 2002-10-01 | Human Genome Sciences, Inc. | Chemokine β-4 polypeptides |
US6042821A (en) * | 1995-11-21 | 2000-03-28 | Smithkline Beecham Corporation | Method of treating sepsis with chemokines |
US6290948B1 (en) | 1996-05-14 | 2001-09-18 | Smithkline Beecham Corporation | Method of treating sepsis and ARDS using chamohine beta-10 |
PL340754A1 (en) * | 1997-11-26 | 2001-02-26 | Smithkline Beecham Corp | Method activating haemoblast-type stem cells |
WO2000074629A2 (en) * | 1999-06-08 | 2000-12-14 | Transgene S.A. | Composition for implementing a cytotoxic, in particular an antitumoral or antiviral, treatment in a mammal |
EP1303292A4 (en) * | 2000-06-30 | 2007-08-22 | Smithkline Beecham Corp | Chemokine conjugates |
JP3563366B2 (en) | 2001-05-07 | 2004-09-08 | 独立行政法人 科学技術振興機構 | Protein multimers with unfolding activity on protein conformation |
IL146970A0 (en) * | 2001-12-06 | 2002-08-14 | Yeda Res & Dev | Migration of haematopoietic stem cells and progenitor cells to the liver |
WO2003092597A2 (en) | 2002-05-01 | 2003-11-13 | Human Genome Sciences, Inc. | Antibodies that specifically bind to chemokine beta-4 |
SG10201509499RA (en) | 2010-11-19 | 2015-12-30 | Eisai R&D Man Co Ltd | Neutralizing anti-ccl20 antibodies |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0713495B1 (en) * | 1993-06-08 | 2003-11-05 | Smithkline Beecham Corporation | Methods of enhancing bioactivity of chemokines |
GB9426012D0 (en) * | 1994-12-22 | 1995-02-22 | British Biotech Pharm | Mobilisation of haematopoietic cells |
GB9517014D0 (en) * | 1995-08-19 | 1995-10-25 | British Biotech Pharm | Haematopoietic recovery |
-
1996
- 1996-10-23 ZA ZA968896A patent/ZA968896B/en unknown
- 1996-10-24 BR BR9611173A patent/BR9611173A/en not_active Application Discontinuation
- 1996-10-24 JP JP9516787A patent/JPH11512747A/en active Pending
- 1996-10-24 NZ NZ321789A patent/NZ321789A/en unknown
- 1996-10-24 WO PCT/US1996/017074 patent/WO1997015595A1/en not_active Application Discontinuation
- 1996-10-24 HU HU9802531A patent/HUP9802531A3/en unknown
- 1996-10-24 AU AU75209/96A patent/AU712235B2/en not_active Ceased
- 1996-10-24 CZ CZ981202A patent/CZ120298A3/en unknown
- 1996-10-24 TR TR1998/00742T patent/TR199800742T2/en unknown
- 1996-10-24 AR ARP960104890A patent/AR004093A1/en unknown
- 1996-10-24 EP EP96937739A patent/EP0866806A4/en not_active Withdrawn
- 1996-10-24 PL PL96326364A patent/PL326364A1/en unknown
- 1996-10-24 KR KR1019980702932A patent/KR19990066997A/en not_active Application Discontinuation
-
1998
- 1998-04-23 NO NO981818A patent/NO981818L/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
BR9611173A (en) | 1999-03-30 |
AU712235B2 (en) | 1999-11-04 |
JPH11512747A (en) | 1999-11-02 |
EP0866806A4 (en) | 2002-01-09 |
MX9803217A (en) | 1998-09-30 |
NZ321789A (en) | 2000-07-28 |
TR199800742T2 (en) | 1998-08-21 |
WO1997015595A1 (en) | 1997-05-01 |
NO981818D0 (en) | 1998-04-23 |
PL326364A1 (en) | 1998-09-14 |
AU7520996A (en) | 1997-05-15 |
NO981818L (en) | 1998-06-17 |
EP0866806A1 (en) | 1998-09-30 |
CZ120298A3 (en) | 1998-09-16 |
HUP9802531A3 (en) | 2001-08-28 |
ZA968896B (en) | 1997-04-24 |
HUP9802531A2 (en) | 1999-02-01 |
KR19990066997A (en) | 1999-08-16 |
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