ES2143940A1 - Process for the selective preparation of [alpha]-hydroxy acid derivatives - Google Patents
Process for the selective preparation of [alpha]-hydroxy acid derivativesInfo
- Publication number
- ES2143940A1 ES2143940A1 ES009800415A ES9800415A ES2143940A1 ES 2143940 A1 ES2143940 A1 ES 2143940A1 ES 009800415 A ES009800415 A ES 009800415A ES 9800415 A ES9800415 A ES 9800415A ES 2143940 A1 ES2143940 A1 ES 2143940A1
- Authority
- ES
- Spain
- Prior art keywords
- hydroxy acid
- alpha
- acid derivatives
- selective preparation
- agents
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
The process is based on simply mixing the α-hydroxy acid with alcohols or fatty acids, the addition of solvent and enzyme. The use of lipases makes it possible to obtain, in regioselective form and without catalysts or toxic agents, hydroxy acid esters in exclusively monomeric form. Control of the water content of the medium is of great importance. The products obtained are used as emulsifiers, moisturizing agents, and in various cosmetic and pharmaceutical formulations.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES9800415A ES2143940B1 (en) | 1998-02-26 | 1998-02-26 | SELECTIVE PREPARATION PROCEDURE OF ALPHA-HYDROXIACID DERIVATIVES. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES9800415A ES2143940B1 (en) | 1998-02-26 | 1998-02-26 | SELECTIVE PREPARATION PROCEDURE OF ALPHA-HYDROXIACID DERIVATIVES. |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2143940A1 true ES2143940A1 (en) | 2000-05-16 |
ES2143940B1 ES2143940B1 (en) | 2000-12-16 |
Family
ID=8302929
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES9800415A Expired - Fee Related ES2143940B1 (en) | 1998-02-26 | 1998-02-26 | SELECTIVE PREPARATION PROCEDURE OF ALPHA-HYDROXIACID DERIVATIVES. |
Country Status (1)
Country | Link |
---|---|
ES (1) | ES2143940B1 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7863025B2 (en) | 2004-10-18 | 2011-01-04 | Chemic Laboratories, Inc. | Synthesis of fatty alcohol esters of alpha-hydroxy carboxylic acids and their use as percutaneous absorption enhancers |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0424130A1 (en) * | 1989-10-20 | 1991-04-24 | Unichema Chemie B.V. | Supported enzyme |
EP0506159A1 (en) * | 1991-03-19 | 1992-09-30 | Unichema Chemie B.V. | Esterification process |
WO1994012652A1 (en) * | 1992-11-30 | 1994-06-09 | Baxenden Chemicals Limited | Enzymatic synthesis |
-
1998
- 1998-02-26 ES ES9800415A patent/ES2143940B1/en not_active Expired - Fee Related
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0424130A1 (en) * | 1989-10-20 | 1991-04-24 | Unichema Chemie B.V. | Supported enzyme |
EP0506159A1 (en) * | 1991-03-19 | 1992-09-30 | Unichema Chemie B.V. | Esterification process |
WO1994012652A1 (en) * | 1992-11-30 | 1994-06-09 | Baxenden Chemicals Limited | Enzymatic synthesis |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7863025B2 (en) | 2004-10-18 | 2011-01-04 | Chemic Laboratories, Inc. | Synthesis of fatty alcohol esters of alpha-hydroxy carboxylic acids and their use as percutaneous absorption enhancers |
US8936922B2 (en) | 2004-10-18 | 2015-01-20 | Chemsmart, Llc | Synthesis of fatty alcohol esters of alpha-hydroxy carboxylic acids and their use as percutaneous absorption enhancers |
Also Published As
Publication number | Publication date |
---|---|
ES2143940B1 (en) | 2000-12-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EC2A | Search report published |
Date of ref document: 20000516 Kind code of ref document: A1 Effective date: 20000516 |
|
FD2A | Announcement of lapse in spain |
Effective date: 20180807 |