ES2139729T3 - Uso del factor xiii aplicado topicamente para la inhibicion de hemorragias. - Google Patents

Uso del factor xiii aplicado topicamente para la inhibicion de hemorragias.

Info

Publication number
ES2139729T3
ES2139729T3 ES94900578T ES94900578T ES2139729T3 ES 2139729 T3 ES2139729 T3 ES 2139729T3 ES 94900578 T ES94900578 T ES 94900578T ES 94900578 T ES94900578 T ES 94900578T ES 2139729 T3 ES2139729 T3 ES 2139729T3
Authority
ES
Spain
Prior art keywords
bleeding
factor xiii
inhibition
applied topically
sites
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94900578T
Other languages
English (en)
Inventor
Marc R Mayberg
Martin William Edwards
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zymogenetics Inc
Original Assignee
Zymogenetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zymogenetics Inc filed Critical Zymogenetics Inc
Application granted granted Critical
Publication of ES2139729T3 publication Critical patent/ES2139729T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/45—Transferases (2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

Abstract

EL PRESENTE INVENTO PROPORCIONA METODOS PARA INHIBIR EL SANGRADO RETARDADO DE HERIDAS Y LAS HEMORRAGIAS POST-OPERATORIAS A TRAVES DE LA APLICACION TOPICA DE FACTOR XIII. LOS METODOS SE PUEDEN EMPLEAR EN LUGARES QUIRURGICOS, INCLUYENDO LUGARES INTRACRANEALES, Y EN PACIENTES COAGULOPATICOS.
ES94900578T 1992-11-12 1993-11-09 Uso del factor xiii aplicado topicamente para la inhibicion de hemorragias. Expired - Lifetime ES2139729T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US97502692A 1992-11-12 1992-11-12

Publications (1)

Publication Number Publication Date
ES2139729T3 true ES2139729T3 (es) 2000-02-16

Family

ID=25522630

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94900578T Expired - Lifetime ES2139729T3 (es) 1992-11-12 1993-11-09 Uso del factor xiii aplicado topicamente para la inhibicion de hemorragias.

Country Status (9)

Country Link
EP (1) EP0669834B1 (es)
JP (1) JP2004231664A (es)
AT (1) ATE184199T1 (es)
CA (1) CA2149209C (es)
DE (1) DE69326349T2 (es)
DK (1) DK0669834T3 (es)
ES (1) ES2139729T3 (es)
GR (1) GR3031890T3 (es)
WO (1) WO1994011022A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07328108A (ja) * 1994-06-10 1995-12-19 Ajinomoto Co Inc 生体組織接着剤及び血液凝固剤
DE60213968T2 (de) * 2001-02-21 2007-08-30 Zymogenetics, Inc., Seattle Blutgerinnungsfaktor xiii zur behandlung von plättchenfunktionsstörungen
WO2005115442A1 (en) * 2004-05-25 2005-12-08 Novo Nordisk Health Care Ag Use of coagulation factor xiii for treatment of post surgical bleedings
US20080176789A1 (en) 2004-08-27 2008-07-24 Novc Nordisk Healthcare A/G Purification of Factor Xlll Polypeptides From Biological Materials
US9358318B2 (en) 2004-10-20 2016-06-07 Ethicon, Inc. Method of making a reinforced absorbable multilayered hemostatic wound dressing
EP2052746B1 (en) 2004-10-20 2014-11-26 Ethicon, Inc. Absorbable hemostat

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4265233A (en) * 1978-04-12 1981-05-05 Unitika Ltd. Material for wound healing
WO1989001512A1 (en) * 1987-08-17 1989-02-23 The Liposome Company, Inc. A sponge enzyme having transglutaminase-like activity
JPH01216939A (ja) * 1988-02-24 1989-08-30 Hoechst Japan Kk 末熟児頭蓋内出血阻止剤
DE3829524A1 (de) * 1988-08-31 1990-03-01 Behringwerke Ag Verwendung von transglutaminasen als immunsuppressiva

Also Published As

Publication number Publication date
GR3031890T3 (en) 2000-02-29
JP3884064B2 (ja) 2007-02-21
DE69326349T2 (de) 2000-03-02
WO1994011022A1 (en) 1994-05-26
EP0669834A1 (en) 1995-09-06
ATE184199T1 (de) 1999-09-15
DE69326349D1 (de) 1999-10-14
JP2004231664A (ja) 2004-08-19
EP0669834B1 (en) 1999-09-08
JPH08505129A (ja) 1996-06-04
CA2149209A1 (en) 1994-05-26
CA2149209C (en) 2000-08-01
DK0669834T3 (da) 2000-04-17

Similar Documents

Publication Publication Date Title
BR9406080A (pt) Compostos que tem tanto antividade de anaonista potente de calcio como de antioxidante e uso dos mesmos como agentes citoprotetores
ES2187665T3 (es) Uso de la il-10 para curar heridas con una cicatrizacion reducida.
BR0014384A (pt) Compostos para o tratamento da isquémia
BR9708632A (pt) Composto calcilìticos
ES2124793T3 (es) Derivados de rapamicina alquilados en o y su uso, particularmente como inmunosupresores.
CA2241981A1 (en) Method of inhibiting photoaging of skin
ES2194308T3 (es) Utilizacion de sustancias con una actividad de oxitocina en la preparacion de medicamentos para la curacion de heridas.
BR0200921A (pt) Uso de produtos de legume para o tratamento de agressões externas
SE9604348D0 (sv) Användning av hydroxyguanidiner
RS49599B (sr) Upotreba inhibitora h+, k+-atp-aze i glukokortikoida i farmaceutska formulacija
TR199801365T2 (xx) �yile�me s�recinin kontrol�.
ES2139729T3 (es) Uso del factor xiii aplicado topicamente para la inhibicion de hemorragias.
BR9908713A (pt) Uso de selegilina ou desmetil-selegilina para tratamento de feridas, queimaduras e danos dermatológicos
DE69705110T2 (de) Topische pharmazeutische zusammensetzungen, welche heparin enthalten
ES2140575T3 (es) L-lisil-glicil-l-histidina y agente terapeutico para curar heridas que lo contiene.
BR0109896A (pt) Composição tópica em gel, curativo de feridas, seu método e uso
DE69906701D1 (de) Topische verwendung von loperamid zur behandlung mikrobieller infektionen
DE60003074D1 (de) Fusidinsäure-derivate
KR910700039A (ko) 탈모증 치료용의 미녹시딜 및 혈관수축제 조성물
DK0895478T3 (da) Bestanddel B som ardanner
BR9907438A (pt) Pomada de repolho, uso em curativos tópicos
BR0015424A (pt) Análogos de ácido hidroxieicosatetraenóico e, métodos de seu uso em tratamento de distúrbios de olho seco
RU96122690A (ru) Лекарственное средство для наружного лечения псориаза
UA32315A (uk) Спосіб накладання шкірного шва
ITGE940025A0 (it) Preparazione farmaceutica ad uso topico per la cura della psoriasi e di altre dermatosi.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 669834

Country of ref document: ES