ES2139613T3 - Benzodiazepinas y composiciones para el tratamiento de trastornos de la ansiedad y el panico, y de la epilepsia idiopatica y psicomotora. - Google Patents

Benzodiazepinas y composiciones para el tratamiento de trastornos de la ansiedad y el panico, y de la epilepsia idiopatica y psicomotora.

Info

Publication number
ES2139613T3
ES2139613T3 ES93109292T ES93109292T ES2139613T3 ES 2139613 T3 ES2139613 T3 ES 2139613T3 ES 93109292 T ES93109292 T ES 93109292T ES 93109292 T ES93109292 T ES 93109292T ES 2139613 T3 ES2139613 T3 ES 2139613T3
Authority
ES
Spain
Prior art keywords
anxiety
psychomotoric
idiopatic
benzodiazepines
epilepsy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93109292T
Other languages
English (en)
Inventor
Armin Walser
Alessandro Guidotti
Erminio Costa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
FIDIA RESEARCH FOUNDATION
F Hoffmann La Roche AG
Original Assignee
FIDIA RESEARCH FOUNDATION
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by FIDIA RESEARCH FOUNDATION, F Hoffmann La Roche AG filed Critical FIDIA RESEARCH FOUNDATION
Application granted granted Critical
Publication of ES2139613T3 publication Critical patent/ES2139613T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

LA PRESENTE INVENCION MUESTRA UNOS COMPONENTES DE IMIDAZO[1,5-A] [1,4]BENZODIACEPINA-3-CARBOXAMIDA DE FORMULA (I) EN LA QUE R ES HIDROGENO,FORM (II),(III),(IV),(V) O (VI), O UNA DE SUS SALES ACEPTABLES FARMACEUTICAMENTE.ESTOS COMPONENTES Y SUS SALES POSEEN ACTIVIDAD ANTI-ANSIEDAD Y ANTI-EPILEPSIA.
ES93109292T 1992-06-09 1993-06-09 Benzodiazepinas y composiciones para el tratamiento de trastornos de la ansiedad y el panico, y de la epilepsia idiopatica y psicomotora. Expired - Lifetime ES2139613T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/895,851 US5317018A (en) 1992-06-09 1992-06-09 Benzodiazepines and compositions for treating anxiety and panic disorders, and idiopathic and psychomotor epilepsy

Publications (1)

Publication Number Publication Date
ES2139613T3 true ES2139613T3 (es) 2000-02-16

Family

ID=25405182

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93109292T Expired - Lifetime ES2139613T3 (es) 1992-06-09 1993-06-09 Benzodiazepinas y composiciones para el tratamiento de trastornos de la ansiedad y el panico, y de la epilepsia idiopatica y psicomotora.

Country Status (11)

Country Link
US (1) US5317018A (es)
EP (1) EP0573982B1 (es)
JP (1) JP3367951B2 (es)
AT (1) ATE184606T1 (es)
AU (1) AU4530393A (es)
CA (1) CA2137668C (es)
DE (1) DE69326386T2 (es)
DK (1) DK0573982T3 (es)
ES (1) ES2139613T3 (es)
GR (1) GR3032120T3 (es)
WO (1) WO1993025554A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5706829A (en) * 1996-06-06 1998-01-13 Creighton University Method for treating neurocardiogenic syncope
US6964958B2 (en) * 2001-09-28 2005-11-15 James Auta Method of simultaneously treating sensory auditory gating deficit and associated psychosis in schizophrenia and bipolar disorder patients with mania
EP2148944A1 (en) * 2007-05-25 2010-02-03 Burnham Institute for Medical Research Inhibitors of thapsigargin-induced cell death
US8119629B2 (en) * 2007-10-03 2012-02-21 Bristol-Meyers Squibb Company Carboxamide GABAA α2 modulators
US20090270373A1 (en) * 2008-04-11 2009-10-29 Cypress Biosciences, Inc. Treatment of down syndrom with benzodiazepine receptor antagonists
JP7013446B2 (ja) 2016-08-16 2022-02-15 ユーダブリューエム・リサーチ・ファウンデーション，インコーポレーテッド Ｇａｂａ（ａ）受容体モジュレーター、及び、喘息における気道過敏及び炎症を抑制するための方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4280957A (en) * 1974-09-11 1981-07-28 Hoffmann-La Roche Inc. Imidazodiazepines and processes therefor
US4118386A (en) * 1977-04-04 1978-10-03 Hoffmann-La Roche Inc. Synthesis of imidazo[1,5-a]diazepine-3-carboxylates
DK151808C (da) * 1982-11-16 1988-06-20 Ferrosan As Analogifremgangsmaade til fremstilling af oxadiazolylimidazo-oe1,4aa-benzodiazepinderivater
ZA845757B (en) * 1983-08-25 1985-04-24 Hoffmann La Roche Benzodiazepine derivatives
IE910939A1 (en) * 1990-04-13 1991-10-23 Neurosearch As Use of benzodiazepine compounds
CA2055308A1 (en) * 1990-11-29 1992-05-30 Roman Amrein Imidazobenzodiazepine for the treatment of sleep disorders

Also Published As

Publication number Publication date
CA2137668A1 (en) 1993-12-23
DE69326386D1 (de) 1999-10-21
CA2137668C (en) 2005-08-23
JPH08502027A (ja) 1996-03-05
WO1993025554A1 (en) 1993-12-23
AU4530393A (en) 1994-01-04
DK0573982T3 (da) 2000-03-20
US5317018A (en) 1994-05-31
EP0573982A1 (en) 1993-12-15
GR3032120T3 (en) 2000-04-27
JP3367951B2 (ja) 2003-01-20
EP0573982B1 (en) 1999-09-15
ATE184606T1 (de) 1999-10-15
DE69326386T2 (de) 2000-06-15

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