ES2138017T3 - Uso de n-(piridinil)-1h-indol-1-aminas para la preparacion de un medicamento para el tratamiento de trastornos obsesivo-compulsivos. - Google Patents

Uso de n-(piridinil)-1h-indol-1-aminas para la preparacion de un medicamento para el tratamiento de trastornos obsesivo-compulsivos.

Info

Publication number
ES2138017T3
ES2138017T3 ES94110875T ES94110875T ES2138017T3 ES 2138017 T3 ES2138017 T3 ES 2138017T3 ES 94110875 T ES94110875 T ES 94110875T ES 94110875 T ES94110875 T ES 94110875T ES 2138017 T3 ES2138017 T3 ES 2138017T3
Authority
ES
Spain
Prior art keywords
preparation
treatment
obsessive
piridinil
indol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94110875T
Other languages
English (en)
Inventor
Sathapana Kongsamut
Craig Paul Smith
Ann Theresa Woods
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Hoechst Marion Roussel Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Inc
Application granted granted Critical
Publication of ES2138017T3 publication Critical patent/ES2138017T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE AL USO DE UN COMPUESTO DE FORMULA I, DONDE M ES 0, 1 O 2; R ES HALOGENO, ALQUILO INFERIOR, ALCOXI INFERIOR, HIDROXI, NITRO, AMINO, ALQUILAMINO INFERIOR, O DIALQUILAMINO INFERIOR; R1 ES H O ALQUILO INFERIOR; R2 ES H O ALQUILO INFERIOR; Y R3 ES H, HALOGENO O ALQUILO INFERIOR O UNA SAL DE ADICION FARMACEUTICAMENTE ACEPTABLE DE ESTE, PARA LA PREPARACION DE MEDICAMENTOS, PARA EL TRATAMIENTO DE TRASTORNOS COMPULSIVOS OBSESIVOS.
ES94110875T 1993-07-19 1994-07-13 Uso de n-(piridinil)-1h-indol-1-aminas para la preparacion de un medicamento para el tratamiento de trastornos obsesivo-compulsivos. Expired - Lifetime ES2138017T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/092,848 US5356910A (en) 1993-07-19 1993-07-19 Use of N-(pyridinyl)-1H-indol-1-amines for the treatment of obsessive-compulsive disorder

Publications (1)

Publication Number Publication Date
ES2138017T3 true ES2138017T3 (es) 2000-01-01

Family

ID=22235450

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94110875T Expired - Lifetime ES2138017T3 (es) 1993-07-19 1994-07-13 Uso de n-(piridinil)-1h-indol-1-aminas para la preparacion de un medicamento para el tratamiento de trastornos obsesivo-compulsivos.

Country Status (21)

Country Link
US (1) US5356910A (es)
EP (1) EP0635269B1 (es)
JP (1) JP2807633B2 (es)
KR (1) KR100325276B1 (es)
AT (1) ATE186215T1 (es)
AU (1) AU673747B2 (es)
CA (1) CA2128312C (es)
CZ (1) CZ288593B6 (es)
DE (1) DE69421457T2 (es)
DK (1) DK0635269T3 (es)
EG (1) EG20716A (es)
ES (1) ES2138017T3 (es)
GR (1) GR3032292T3 (es)
HU (1) HU217063B (es)
MX (1) MX9405209A (es)
NO (1) NO306597B1 (es)
NZ (1) NZ264015A (es)
PL (1) PL304335A1 (es)
RU (1) RU2164795C2 (es)
TW (1) TW349864B (es)
ZA (1) ZA945236B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5459274A (en) * 1994-05-13 1995-10-17 Hoechst-Roussel Pharmaceuticals Inc. Preparation of N-alkyl-N-pyridinyl-1H-indol-1-amines
US5776955A (en) * 1995-07-27 1998-07-07 Hoechst Marion Roussel, Inc. Use of unsubstituted and substituted n-(pyrrol-1-yl)pyridinamines as anticonvulsant agents
CN1184969C (zh) * 1995-07-27 2005-01-19 阿温蒂斯药物公司 未取代和取代的n－(吡咯－1－基)吡啶胺作为抗惊厥药的用途
JP4608723B2 (ja) * 1999-03-10 2011-01-12 東ソー株式会社 置換インドール誘導体の製造方法
GT200500063A (es) * 2004-04-01 2005-10-14 Metodo para tratar la esquizofrenia y/o anormalidades glucoregulatorias
FR2892022B1 (fr) * 2005-10-19 2008-01-04 Urogene Sa Traitement des symptomes de l'irritation de la vessie
FR2892021B1 (fr) * 2005-10-19 2008-01-04 Urogene Traitement de l'incontinence urinaire d'effort et mixte
FR2897614B1 (fr) * 2006-02-20 2008-05-23 Urogene Forme cristalline du chlorhydrate de la besipirdine, procedes de preparation et utilisations

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4970218A (en) * 1987-04-24 1990-11-13 Hoechst-Roussel Pharmaceuticals Inc. N-(pyridinyl)-1H-indol-1-amines
US4880822A (en) * 1987-04-24 1989-11-14 Hoechst-Roussel Pharmaceuticals, Inc. N-(pyridinyl)-1H-indol-1-amines
ATE115143T1 (de) 1987-04-24 1994-12-15 Hoechst Roussel Pharma N-(pyridinyl)-1h-indol-1-amine, verfahren zu deren herstellung und ihre verwendung als arzneimittel.
US5179099A (en) * 1989-08-02 1993-01-12 Hoechst-Roussel Pharmaceuticals Incorporated 2,3-dihydro-1-(pyridinylamino)-indoles
US5214038A (en) * 1991-04-15 1993-05-25 Hoechst-Roussel Pharmaceuticals Inc. 1-(pyrido[3,4-b]-1,4-oxazinyl-4-yl)-1H-indoles and intermediates for the preparation thereof
US5177088A (en) 1991-04-17 1993-01-05 Hoechst-Roussel Pharmaceuticals Incorporated Substituted 3-(pyridinylamino)-indoles
US5185350A (en) 1991-09-23 1993-02-09 Hoechst-Roussel Pharmaceuticals Incorporated Substituted pyridinylamino-1h-indoles,1h-indazoles,2h-indazoles, benzo (b)thiophenes and 1,2-benzisothiazoles

Also Published As

Publication number Publication date
DE69421457D1 (de) 1999-12-09
KR950002761A (ko) 1995-02-16
ATE186215T1 (de) 1999-11-15
US5356910A (en) 1994-10-18
NZ264015A (en) 1997-07-27
DE69421457T2 (de) 2000-05-04
EP0635269B1 (en) 1999-11-03
AU673747B2 (en) 1996-11-21
HU217063B (hu) 1999-11-29
GR3032292T3 (en) 2000-04-27
HUT69709A (en) 1995-09-28
KR100325276B1 (ko) 2002-09-25
EG20716A (en) 1999-12-29
PL304335A1 (en) 1995-01-23
AU6753194A (en) 1995-01-27
NO942695L (no) 1995-01-20
HU9402124D0 (en) 1994-09-28
MX9405209A (es) 1995-01-31
RU94026084A (ru) 1996-08-27
CZ173094A3 (en) 1995-02-15
CA2128312C (en) 2004-09-28
JP2807633B2 (ja) 1998-10-08
NO942695D0 (no) 1994-07-18
ZA945236B (en) 1995-02-28
CZ288593B6 (cs) 2001-07-11
TW349864B (en) 1999-01-11
CA2128312A1 (en) 1995-01-20
RU2164795C2 (ru) 2001-04-10
EP0635269A1 (en) 1995-01-25
JPH0753376A (ja) 1995-02-28
DK0635269T3 (da) 2000-04-25
NO306597B1 (no) 1999-11-29

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