ES2136457T3 - Dimeros unidos covalentemente de antibioticos glucopeptidicos. - Google Patents

Dimeros unidos covalentemente de antibioticos glucopeptidicos.

Info

Publication number
ES2136457T3
ES2136457T3 ES97302416T ES97302416T ES2136457T3 ES 2136457 T3 ES2136457 T3 ES 2136457T3 ES 97302416 T ES97302416 T ES 97302416T ES 97302416 T ES97302416 T ES 97302416T ES 2136457 T3 ES2136457 T3 ES 2136457T3
Authority
ES
Spain
Prior art keywords
dimers
glucopeptidic
antibiotics
covalently
united
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97302416T
Other languages
English (en)
Inventor
Douglas Richard Stack
Richard Craig Thompson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Application granted granted Critical
Publication of ES2136457T3 publication Critical patent/ES2136457T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/006—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
    • C07K9/008—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A CIERTOS DIMEROS DE GLUCOPEPTIDOS EN LOS QUE SE UNEN COVALENTEMENTE DOS UNIDADES DE GLUCOPEPTIDOS ENTRE SI MEDIANTE UNA AMINA O UN SACARIDO MODIFICABLE. ESTOS DIMEROS SON UTILES COMO ANTIBACTERIANOS, ESPECIALMENTE PARA EL CONTROL DE BACTERIAS GRAM POSITIVAS; LOS COMPUESTOS SON PARTICULARMENTE UTILES PARA EL CONTROL DE CEPAS BACTERIANAS RESISTENTES, COMO LOS ENTEROCOCOS RESISTENTES A VANCOMICINA ("VRE").
ES97302416T 1996-04-12 1997-04-08 Dimeros unidos covalentemente de antibioticos glucopeptidicos. Expired - Lifetime ES2136457T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1533096P 1996-04-12 1996-04-12
US3173696P 1996-11-25 1996-11-25

Publications (1)

Publication Number Publication Date
ES2136457T3 true ES2136457T3 (es) 1999-11-16

Family

ID=26687247

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97302416T Expired - Lifetime ES2136457T3 (es) 1996-04-12 1997-04-08 Dimeros unidos covalentemente de antibioticos glucopeptidicos.

Country Status (8)

Country Link
EP (1) EP0801075B1 (es)
AT (1) ATE181927T1 (es)
AU (1) AU2441697A (es)
DE (1) DE69700308T2 (es)
DK (1) DK0801075T3 (es)
ES (1) ES2136457T3 (es)
GR (1) GR3031302T3 (es)
WO (1) WO1997038702A1 (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5840684A (en) * 1994-01-28 1998-11-24 Eli Lilly And Company Glycopeptide antibiotic derivatives
US5977063A (en) * 1997-05-20 1999-11-02 Eli Lilly And Company Alkylated hexapeptides
US5919771A (en) * 1997-05-20 1999-07-06 Eli Lilly And Company Urea and thiourea derivatives of glycopeptides
US6518242B1 (en) 1998-02-20 2003-02-11 Theravance, Inc. Derivatives of glycopeptide antibacterial agents
IT1307018B1 (it) * 1998-02-20 2001-10-23 Advanced Medicine Inc Agenti antibatterici.
CN1249081C (zh) 1998-12-23 2006-04-05 施万制药 糖肽衍生物或含有它们的药物组合物
US7119061B2 (en) 2002-11-18 2006-10-10 Vicuron Pharmaceuticals, Inc. Dalbavancin compositions for treatment of bacterial infections
US20060074014A1 (en) 2002-11-18 2006-04-06 Vicuron Pharmaceuticals Inc. Dalbavancin compositions for treatment of bacterial infections
DK1565201T3 (en) 2002-11-18 2019-02-25 Vicuron Pharmaceuticals Llc METHODS OF ADMINISTRATING DALBAVANCIN TO TREAT Bacterial Infections
KR20070092719A (ko) 2004-11-29 2007-09-13 고쿠리츠 다이가쿠 호우징 나고야 다이가쿠 글리코펩타이드 항생 물질 모노머 유도체
WO2006057288A1 (ja) * 2004-11-29 2006-06-01 National University Corporation Nagoya University グリコペプチド抗生物質ダイマー誘導体
US8652504B2 (en) 2005-09-22 2014-02-18 Medivas, Llc Solid polymer delivery compositions and methods for use thereof
EP1926780B1 (en) 2005-09-22 2013-08-14 Medivas, LLC Bis-( -amino)-diol-diester-containing poly(ester amide) and poly(ester urethane) compositions and methods of use
WO2009081958A1 (ja) 2007-12-26 2009-07-02 Shionogi & Co., Ltd. グリコペプチド抗生物質配糖化誘導体
US8841440B2 (en) 2008-04-01 2014-09-23 Cornell University Organo-soluble chitosan salts and chitosan-derived biomaterials prepared thereof

Also Published As

Publication number Publication date
EP0801075B1 (en) 1999-07-07
WO1997038702A1 (en) 1997-10-23
DE69700308D1 (de) 1999-08-12
DE69700308T2 (de) 1999-11-18
GR3031302T3 (en) 1999-12-31
AU2441697A (en) 1997-11-07
EP0801075A1 (en) 1997-10-15
DK0801075T3 (da) 1999-11-22
ATE181927T1 (de) 1999-07-15

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