ES2136199T3 - Expresion multicistronica de genes recombinantes en celulas bacterianas. - Google Patents
Expresion multicistronica de genes recombinantes en celulas bacterianas.Info
- Publication number
- ES2136199T3 ES2136199T3 ES94918392T ES94918392T ES2136199T3 ES 2136199 T3 ES2136199 T3 ES 2136199T3 ES 94918392 T ES94918392 T ES 94918392T ES 94918392 T ES94918392 T ES 94918392T ES 2136199 T3 ES2136199 T3 ES 2136199T3
- Authority
- ES
- Spain
- Prior art keywords
- bacterial cells
- recombinant genes
- multicistronic expression
- expression
- proteins
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/49—Platelet-derived growth factor [PDGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
- C12N15/73—Expression systems using phage (lambda) regulatory sequences
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Toxicology (AREA)
- Physics & Mathematics (AREA)
- Virology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Dermatology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
LA INVENCION SE REFIERE A PROCESOS RECOMBINANTES PARA LA ELABORACION DE PROTEINAS HETEROMETRAS EN CELULAS EN CELULAS BACTERIALES UTILIZANDO VECTORES DE EXPRESION MULTICISTRONICA. CON LA AYUDA DEL PROCESO DE ACUERDO CON LA INVENCION ES POSIBLE LA EXPRESION DE LOS COMPONENTES O DE LAS SUBUNIDADES DE LAS PROTEINAS EN UNA Y EN LA MISMA CELULA BACTERIAL, CON CONTROL INDIVIDUAL A TRAVES DE LAS RELACIONES DE EXPRESION.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4319708A DE4319708A1 (de) | 1993-06-10 | 1993-06-10 | Multicistronische Expression rekombinanter Gene in Bakterienzellen |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2136199T3 true ES2136199T3 (es) | 1999-11-16 |
Family
ID=6490331
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES94918392T Expired - Lifetime ES2136199T3 (es) | 1993-06-10 | 1994-06-06 | Expresion multicistronica de genes recombinantes en celulas bacterianas. |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0701616B1 (es) |
JP (1) | JPH09501825A (es) |
DE (2) | DE4319708A1 (es) |
ES (1) | ES2136199T3 (es) |
WO (1) | WO1994029462A1 (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20040041639A (ko) * | 1995-04-24 | 2004-05-17 | 크로막솜 코포레이티드 | 새로운 대사 경로를 만들고 이를 스크리닝하는 방법 |
US5783431A (en) * | 1996-04-24 | 1998-07-21 | Chromaxome Corporation | Methods for generating and screening novel metabolic pathways |
US6242211B1 (en) | 1996-04-24 | 2001-06-05 | Terragen Discovery, Inc. | Methods for generating and screening novel metabolic pathways |
EP2484774A3 (en) | 2005-07-21 | 2012-11-14 | Abbott Laboratories | Multiple gene expression including sorf contructs and methods with polyproteins, pro-proteins, and proteolysis |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2091749T3 (es) * | 1987-04-22 | 1996-11-16 | Chiron Corp | Produccion por recombinacion de polipeptidos de la cadena a del factor de crecimiento derivado de plaquetas (fcdp). |
GB2214508A (en) * | 1988-01-27 | 1989-09-06 | Bayer Ag | Plasmid vector for the efficient expression of foreign genes fused with newly conceived transcriptional and translational signal sequences. |
-
1993
- 1993-06-10 DE DE4319708A patent/DE4319708A1/de not_active Withdrawn
-
1994
- 1994-06-06 EP EP94918392A patent/EP0701616B1/de not_active Expired - Lifetime
- 1994-06-06 DE DE59408697T patent/DE59408697D1/de not_active Expired - Fee Related
- 1994-06-06 WO PCT/EP1994/001861 patent/WO1994029462A1/de active IP Right Grant
- 1994-06-06 ES ES94918392T patent/ES2136199T3/es not_active Expired - Lifetime
- 1994-06-06 JP JP7501321A patent/JPH09501825A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
DE4319708A1 (de) | 1994-12-15 |
EP0701616B1 (de) | 1999-09-01 |
WO1994029462A1 (de) | 1994-12-22 |
JPH09501825A (ja) | 1997-02-25 |
DE59408697D1 (de) | 1999-10-07 |
EP0701616A1 (de) | 1996-03-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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