ES2135569T3 - Dializador rectificador, biorreactor y membrana. - Google Patents

Dializador rectificador, biorreactor y membrana.

Info

Publication number
ES2135569T3
ES2135569T3 ES94910773T ES94910773T ES2135569T3 ES 2135569 T3 ES2135569 T3 ES 2135569T3 ES 94910773 T ES94910773 T ES 94910773T ES 94910773 T ES94910773 T ES 94910773T ES 2135569 T3 ES2135569 T3 ES 2135569T3
Authority
ES
Spain
Prior art keywords
membranes
dialysis
membrane
solutes
rectification
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94910773T
Other languages
English (en)
Inventor
Norma J Ofsthun
Lee W Henderson
Richard I Brown
Robin G Pauley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Baxter International Inc
Original Assignee
Baxter International Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxter International Inc filed Critical Baxter International Inc
Application granted granted Critical
Publication of ES2135569T3 publication Critical patent/ES2135569T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14—Ultrafiltration; Microfiltration
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/24—Dialysis ; Membrane extraction
    • B01D61/243—Dialysis
    • B01D61/244—Dialysis comprising multiple dialysis steps
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D69/00—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
    • B01D69/02—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor characterised by their properties
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D69/00—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
    • B01D69/08—Hollow fibre membranes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/16—Hollow fibers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Water Supply & Treatment (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • External Artificial Organs (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Manufacture Of Porous Articles, And Recovery And Treatment Of Waste Products (AREA)

Abstract

LA INVENCION PROVEE MEMBRANAS DE PIEL DOBLE UTILES COMO UNA MANERA O MEMBRANAS DE RECTIFICACION QUE REDUCEN LA FILTRACION DE VUELTA DE MOLECULAS SOLUBLES EN LA DIALISIS Y QUE MEJORAN EL SUMINISTRO NUTRIENTE Y EL PRODUCTO SE RECUPERA EN LOS BIOREACTORES DE MEMBRANA. LAS MEMBRANAS SON MATERIALES POLIMERICOS DE PIEL DOBLE PREFERIBLEMENTE EN LA FORMA DE FIBRAS HUECAS. LAS MEMBRANAS TIENEN PIELES DE POLIMERO EN LOS LADOS OPUESTOS CON PERMEABILIDAD DIFERENTE A LOS SOLUTOS Y CARACTERISTICOS COEFICIENTES DE TAMIZACION. LA PIEL EN CADA LATERAL TIENE POROS QUE SON INVISIBLES A LA AMPLIACION DE 10,000 VECES, LA ESTRUCTURA MICROPOROSA ENTRE DICHAS PIELES CONTIENE POROS CAPACES DE RETENER LOS SOLUTOS EN UNA CLASE DE PESO MOLECULAR DE 5000 A 200,000 EN UNA CONCENTRACION INCREMENTADA ENTRE LAS PIELES INTERIOR Y LA EXTERIOR. SON FORMADOS DISPOSITIVOS DE DIALISIS MEJORADOS POR USAR MANOJOS DE LAS MEMBRANAS DE FIBRA HUECA COMO UN MEDIO DE DIALISIS QUE TIENE PROPIEDADES DE RECTIFICACION.
ES94910773T 1993-03-09 1994-02-28 Dializador rectificador, biorreactor y membrana. Expired - Lifetime ES2135569T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US2840093A 1993-03-09 1993-03-09

Publications (1)

Publication Number Publication Date
ES2135569T3 true ES2135569T3 (es) 1999-11-01

Family

ID=21843256

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94910773T Expired - Lifetime ES2135569T3 (es) 1993-03-09 1994-02-28 Dializador rectificador, biorreactor y membrana.

Country Status (10)

Country Link
EP (1) EP0644928B1 (es)
JP (1) JP3396034B2 (es)
KR (1) KR100304224B1 (es)
CN (1) CN1056645C (es)
AT (1) ATE181357T1 (es)
CA (1) CA2134327C (es)
DE (1) DE69419095T2 (es)
ES (1) ES2135569T3 (es)
TW (1) TW243417B (es)
WO (1) WO1994020603A1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5480552A (en) * 1992-01-10 1996-01-02 Baxter International Inc. Method for concentrating a solute with an oscillating filtration device
JP3714686B2 (ja) * 1994-04-27 2005-11-09 旭化成メディカル株式会社 ポリスルホン系中空糸膜及びその製造方法
ATE258592T1 (de) * 1997-07-31 2004-02-15 Roche Diagnostics Gmbh Verfahren und vorrichtung zur durchführung biochemischer reaktionen
ES2639183T3 (es) 2007-09-19 2017-10-25 The Charles Stark Draper Laboratory, Inc. Estructuras microfluídicas con sección transversal circular
US20110082563A1 (en) * 2009-10-05 2011-04-07 The Charles Stark Draper Laboratory, Inc. Microscale multiple-fluid-stream bioreactor for cell culture

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60246812A (ja) * 1984-05-18 1985-12-06 Daicel Chem Ind Ltd ポリスルホン系樹脂製中空糸
EP0198033A4 (en) * 1984-10-09 1989-02-09 Endotronics Inc HOLLOW FIBER CULTURE DEVICE FOR IMPROVING THE INFUSION OF NUTRIENT SUBSTANCES AND THE CONCENTRATION OF PRODUCTS, AND OPERATING METHOD.
DE3583941D1 (de) * 1984-10-30 1991-10-02 Teijin Ltd Hohlfasermembran mit selektiver durchlaessigkeit, deren herstellung und verfahren zur scheidung von plasmakomponenten sowie plasmakomponentabscheider.
DE3851572T2 (de) * 1987-06-12 1995-05-24 Kuraray Co Polysulfon-Hohlfasermembran und Verfahren zu ihrer Herstellung.
FR2640638B1 (fr) * 1988-12-20 1991-02-15 Commissariat Energie Atomique Bioreacteur et dispositif pour la culture de cellules animales
US5240614A (en) * 1992-01-10 1993-08-31 Baxter International Inc. Process for removing unwanted materials from fluids and for producing biological products

Also Published As

Publication number Publication date
CN1103745A (zh) 1995-06-14
EP0644928A1 (en) 1995-03-29
ATE181357T1 (de) 1999-07-15
DE69419095D1 (de) 1999-07-22
EP0644928B1 (en) 1999-06-16
CA2134327A1 (en) 1994-09-15
KR950701378A (ko) 1995-03-23
DE69419095T2 (de) 2000-02-03
WO1994020603A1 (en) 1994-09-15
KR100304224B1 (ko) 2001-11-22
JP3396034B2 (ja) 2003-04-14
TW243417B (es) 1995-03-21
JPH07506496A (ja) 1995-07-20
CN1056645C (zh) 2000-09-20
CA2134327C (en) 2003-12-02

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