ES2130455T3 - Forma de administracion que contiene palmitato de clindamicina con liberacion retardada. - Google Patents

Forma de administracion que contiene palmitato de clindamicina con liberacion retardada.

Info

Publication number
ES2130455T3
ES2130455T3 ES95101011T ES95101011T ES2130455T3 ES 2130455 T3 ES2130455 T3 ES 2130455T3 ES 95101011 T ES95101011 T ES 95101011T ES 95101011 T ES95101011 T ES 95101011T ES 2130455 T3 ES2130455 T3 ES 2130455T3
Authority
ES
Spain
Prior art keywords
palmitate
clindamicine
delayed release
administration containing
implants
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95101011T
Other languages
English (en)
Inventor
Monika Dr Cimbollek
Berthold Dr Nies
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Patent GmbH
Original Assignee
Merck Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent GmbH filed Critical Merck Patent GmbH
Application granted granted Critical
Publication of ES2130455T3 publication Critical patent/ES2130455T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • A61L2300/406—Antibiotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Saccharide Compounds (AREA)
  • Steroid Compounds (AREA)

Abstract

LA INVENCION SE REFIERE A LA UTILIZACION DE PALMITATOCLINDAMICINA PARA LA ELABORACION DE FORMAS DE PRESENTACION FARMACEUTICA CON LIBERACION RETARDADA DE LA SUSTANCIA ACTIVA ANTIBIOTICA CLINDAMICINA ASI COMO FORMAS DE REPRESENTACION CORRESPONDIENTES, QUE CON PREFERENCIA EN FORMA DE CUERPO DE MOLDE-IMPLANTADOS LLEGAN A SER UTILIZADAS.
ES95101011T 1994-02-09 1995-01-26 Forma de administracion que contiene palmitato de clindamicina con liberacion retardada. Expired - Lifetime ES2130455T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4404018A DE4404018A1 (de) 1994-02-09 1994-02-09 Protrahiert freisetzende Darreichungsformen enthaltend Clindamycin-Palmitat

Publications (1)

Publication Number Publication Date
ES2130455T3 true ES2130455T3 (es) 1999-07-01

Family

ID=6509827

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95101011T Expired - Lifetime ES2130455T3 (es) 1994-02-09 1995-01-26 Forma de administracion que contiene palmitato de clindamicina con liberacion retardada.

Country Status (11)

Country Link
US (1) US5607685A (es)
EP (1) EP0667161B1 (es)
JP (1) JPH07277992A (es)
KR (1) KR950031055A (es)
CN (1) CN1111509A (es)
AT (1) ATE177639T1 (es)
CZ (1) CZ32695A3 (es)
DE (2) DE4404018A1 (es)
ES (1) ES2130455T3 (es)
PL (1) PL179298B1 (es)
TW (1) TW282405B (es)

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JP2006111636A (ja) * 1997-12-26 2006-04-27 Astellas Pharma Inc 徐放性医薬組成物
DE19856668A1 (de) * 1998-12-09 2000-06-15 Aesculap Ag & Co Kg Wirkstoffmatrix in Form eines biologisch resorbierbaren porösen Vlieses, Verfahren zu ihrer Herstellung und Verwendung
US7270705B2 (en) * 1999-07-14 2007-09-18 Jiin-Huey Chern Lin Method of increasing working time of tetracalcium phosphate cement paste
US6840995B2 (en) * 1999-07-14 2005-01-11 Calcitec, Inc. Process for producing fast-setting, bioresorbable calcium phosphate cements
US7094282B2 (en) * 2000-07-13 2006-08-22 Calcitec, Inc. Calcium phosphate cement, use and preparation thereof
US6960249B2 (en) * 1999-07-14 2005-11-01 Calcitec, Inc. Tetracalcium phosphate (TTCP) having calcium phosphate whisker on surface
US7169373B2 (en) * 1999-07-14 2007-01-30 Calcitec, Inc. Tetracalcium phosphate (TTCP) having calcium phosphate whisker on surface and process for preparing the same
US6544555B2 (en) 2000-02-24 2003-04-08 Advancis Pharmaceutical Corp. Antibiotic product, use and formulation thereof
US6565882B2 (en) * 2000-02-24 2003-05-20 Advancis Pharmaceutical Corp Antibiotic composition with inhibitor
US7204876B2 (en) * 2000-07-13 2007-04-17 Calcitec, Inc. Calcium phosphate cements made from (TTCP) with surface whiskers and process for preparing same
US7156915B2 (en) * 2000-07-13 2007-01-02 Calcitec, Inc. Tetracalcium phosphate (TTCP) with surface whiskers and method of making same
US6541014B2 (en) * 2000-10-13 2003-04-01 Advancis Pharmaceutical Corp. Antiviral product, use and formulation thereof
US20020068078A1 (en) * 2000-10-13 2002-06-06 Rudnic Edward M. Antifungal product, use and formulation thereof
US20020197314A1 (en) * 2001-02-23 2002-12-26 Rudnic Edward M. Anti-fungal composition
DE10114364A1 (de) * 2001-03-22 2002-10-02 Heraeus Kulzer Gmbh & Co Kg Verfahren zur Herstellung von antibiotischen Kompositen
DE10114244A1 (de) * 2001-03-22 2002-10-02 Heraeus Kulzer Gmbh & Co Kg Antibiotikum-/Antibiotika-Zubereitung mit retardierender Wirkstofffreisetzung
DE10114245A1 (de) * 2001-03-22 2002-10-02 Heraeus Kulzer Gmbh & Co Kg Herstellung und Verwendung einer Antibiotikum-/Antibiotika-Zubereitung
IS6390A (is) 2001-08-31 2003-03-03 Heraeus Kulzer Gmbh & Co. Kg Reynsla af sýklalyfjahúðun skrokka sem í eru örholrými, þannig húðuðum skrokkum og einnig af notkunþeirra
US20040131754A1 (en) * 2001-10-24 2004-07-08 Howmedica Osteonics Corp. Antibiotic calcium phosphate coating
US6596338B2 (en) * 2001-10-24 2003-07-22 Howmedica Osteonics Corp. Antibiotic calcium phosphate coating
MXPA04006163A (es) * 2001-12-20 2004-11-01 Pharmacia Corp Formas de dosis de liberacion sostenida del orden-cero y metodo de fabricacion de las mismas.
US20030216777A1 (en) * 2002-05-16 2003-11-20 Yin-Chun Tien Method of enhancing healing of interfacial gap between bone and tendon or ligament
DE10227935B4 (de) * 2002-06-21 2007-10-04 Heraeus Kulzer Gmbh Verfahren zur Herstellung einer antibiotische Beschichtung von porösen Körpern sowie Verwendung
JP2006507298A (ja) * 2002-10-30 2006-03-02 ファルマシア コーポレーション 経口持続放出型錠剤、ならびにその製造法および使用法
WO2005009364A2 (en) * 2003-07-21 2005-02-03 Advancis Pharmaceutical Corporation Antibiotic product, use and formulation thereof
AU2004258949B2 (en) * 2003-07-21 2011-02-10 Shionogi, Inc. Antibiotic product, use and formulation thereof
JP2006528190A (ja) * 2003-07-21 2006-12-14 アドバンシス ファーマスーティカル コーポレイション 抗生物質製剤、その使用法及び作成方法
US6994726B2 (en) * 2004-05-25 2006-02-07 Calcitec, Inc. Dual function prosthetic bone implant and method for preparing the same
US7163651B2 (en) * 2004-02-19 2007-01-16 Calcitec, Inc. Method for making a porous calcium phosphate article
US7118705B2 (en) * 2003-08-05 2006-10-10 Calcitec, Inc. Method for making a molded calcium phosphate article
JP2007502296A (ja) * 2003-08-11 2007-02-08 アドバンシス ファーマスーティカル コーポレイション ロバストペレット
JP2007502294A (ja) * 2003-08-12 2007-02-08 アドバンシス ファーマスーティカル コーポレイション 抗生物質製剤、その使用法及び作成方法
JP5686494B2 (ja) * 2003-08-29 2015-03-18 シオノギ インコーポレイテッド 抗生物質製剤、その使用法及び作成方法
AU2004273830B2 (en) * 2003-09-15 2011-03-24 Shionogi, Inc. Antibiotic product, use and formulation thereof
US20050101964A1 (en) * 2003-11-07 2005-05-12 Calcitec, Inc. Spinal fusion procedure using an injectable bone substitute
WO2005062898A2 (en) * 2003-12-24 2005-07-14 Advancis Pharmaceutical Corporation Enhanced absorption of modified release dosage forms
AU2005269981A1 (en) * 2004-07-02 2006-02-09 Bonck, John A Tablet for pulsed delivery
DE102005002703C5 (de) 2005-01-19 2013-07-04 Heraeus Kulzer Gmbh Antibiotische Beschichtung von Implantaten sowie Verfahren zur antibiotischen Beschichtung
WO2007056667A2 (en) * 2005-11-04 2007-05-18 Rush University Medical Center Plastic implant impregnated with an antibiotic
US8357394B2 (en) 2005-12-08 2013-01-22 Shionogi Inc. Compositions and methods for improved efficacy of penicillin-type antibiotics
US8778924B2 (en) * 2006-12-04 2014-07-15 Shionogi Inc. Modified release amoxicillin products
DE102006007245A1 (de) * 2006-02-15 2007-08-23 Heraeus Kulzer Gmbh Implantatmaterial
DE102006016598A1 (de) * 2006-04-06 2007-11-15 Heraeus Kulzer Gmbh Beschichtete Vaskulärimplantate
US8299052B2 (en) 2006-05-05 2012-10-30 Shionogi Inc. Pharmaceutical compositions and methods for improved bacterial eradication
DE102007063395A1 (de) * 2007-12-31 2009-07-02 Ossacur Ag Transport-, Weitergabe- und/oder Wirksystem in aseptischer Darreichung
DE102010020940B4 (de) 2010-05-19 2014-09-25 Heraeus Medical Gmbh Antibiotische Beschichtung
DE102010055562B4 (de) 2010-12-23 2015-07-09 Heraeus Medical Gmbh Beschichtungsvorrichtung und Beschichtungsverfahren
DE102010055560B4 (de) 2010-12-23 2017-02-23 Heraeus Medical Gmbh Beschichtungsvorrichtung
DE102010055559B4 (de) 2010-12-23 2015-10-29 Heraeus Medical Gmbh Beschichtungsverfahren und Beschichtungsvorrichtung
DE102010055561B4 (de) 2010-12-23 2015-12-31 Heraeus Medical Gmbh Beschichtungsverfahren und Beschichtungsvorrichtung
KR20140057414A (ko) * 2011-06-22 2014-05-12 바이옴 바이오사이언스 피브이티. 엘티디. 컨쥬게이트계 항진균 및 항세균 프로드러그
DE102011117526B4 (de) 2011-11-03 2015-07-30 Heraeus Medical Gmbh Beschichtungsverfahren und Beschichtungsvorrichtung für medizinische Implantate
CN114230619A (zh) * 2022-01-05 2022-03-25 浙江天台药业股份有限公司 一种盐酸克林霉素棕榈酸酯杂质的分离纯化方法

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US5202128A (en) * 1989-01-06 1993-04-13 F. H. Faulding & Co. Limited Sustained release pharmaceutical composition
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WO1992018101A1 (en) * 1991-04-12 1992-10-29 The Upjohn Company Vaginal drug delivery device

Also Published As

Publication number Publication date
CZ32695A3 (en) 1995-10-18
KR950031055A (ko) 1995-12-18
JPH07277992A (ja) 1995-10-24
ATE177639T1 (de) 1999-04-15
EP0667161B1 (de) 1999-03-17
US5607685A (en) 1997-03-04
DE59505344D1 (de) 1999-04-22
EP0667161A1 (de) 1995-08-16
TW282405B (es) 1996-08-01
CN1111509A (zh) 1995-11-15
PL307159A1 (en) 1995-08-21
DE4404018A1 (de) 1995-08-10
PL179298B1 (pl) 2000-08-31

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