ES2126739T3 - Peliculas a base de copolimeros, sus aplicaciones en sistemas transdermicos y sus procedimientos de preparacion. - Google Patents

Peliculas a base de copolimeros, sus aplicaciones en sistemas transdermicos y sus procedimientos de preparacion.

Info

Publication number
ES2126739T3
ES2126739T3 ES94902838T ES94902838T ES2126739T3 ES 2126739 T3 ES2126739 T3 ES 2126739T3 ES 94902838 T ES94902838 T ES 94902838T ES 94902838 T ES94902838 T ES 94902838T ES 2126739 T3 ES2126739 T3 ES 2126739T3
Authority
ES
Spain
Prior art keywords
acid
copolymers
applications
films based
acrylamide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94902838T
Other languages
English (en)
Inventor
Michel Istin
Jean-Marc Grognet
Charles Darnez
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BIO HOLDING
Original Assignee
BIO HOLDING
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BIO HOLDING filed Critical BIO HOLDING
Application granted granted Critical
Publication of ES2126739T3 publication Critical patent/ES2126739T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007—Drug-containing films, membranes or sheets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Compositions Of Macromolecular Compounds (AREA)

Abstract

PELICULAS A BASE DE COPOLIMEROS, SUS PAPLICACIONES EN SISTEMAS TRANSDERMICOS Y SUS PROCESOS DE PREPARACION, DICHAS PELICULAS ESTAN CONSTITUIDAS POR UN POLIMEROS HIDROFOBO DE TIPO ETILENO/ACETATO DE VINILO (EVA) QUE CONTIENE AL MENOS UN PRINCIPIO ACTIVO Y QUE COMPRENDE 15 A 50% DE INCLUSIONES HIDROFILAS FORMADAS A PARTIR DE AL MENOS UN MONOMERO HIDROFILO ELEGIDO EN EL GRUPO QUE COMPRENDE LA ACRILAMIDA, EL METILOL ACRILAMIDA, EL DIACETONA ACRILAMIDA, EL ACIDO MALEICO, EL ACIDO ACRILICO, EL ACIDO FUMARICO, EL ACIDO ITACONICO, EL ACRILATO DE PROPILENO GLICO, EL METACRILATO DE ETILENO GLICOL, LA METACRILAMINA, EL ACIDO METACRILICO, EL METACRILATO DE PROPILENO GLICOL, EL METACRILATO DE HIDROXIETILO, EL METACRILATO DE DIMETILAMINOETILO, LA N-VINILPIRROLIDONA, EL ACIDO VINILACETICO, LOS ACIDOS VINILSUFONICOS.
ES94902838T 1992-12-21 1993-12-20 Peliculas a base de copolimeros, sus aplicaciones en sistemas transdermicos y sus procedimientos de preparacion. Expired - Lifetime ES2126739T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9215377A FR2699406B1 (fr) 1992-12-21 1992-12-21 Films à base de copolymères, leurs applications dans des systèmes transdermiques et leurs procédés de préparation.

Publications (1)

Publication Number Publication Date
ES2126739T3 true ES2126739T3 (es) 1999-04-01

Family

ID=9436836

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94902838T Expired - Lifetime ES2126739T3 (es) 1992-12-21 1993-12-20 Peliculas a base de copolimeros, sus aplicaciones en sistemas transdermicos y sus procedimientos de preparacion.

Country Status (12)

Country Link
US (1) US5556635A (es)
EP (1) EP0625901B1 (es)
JP (1) JPH07508291A (es)
KR (1) KR100314123B1 (es)
AT (1) ATE172877T1 (es)
CA (1) CA2130332A1 (es)
DE (1) DE69321945T2 (es)
DK (1) DK0625901T3 (es)
ES (1) ES2126739T3 (es)
FR (1) FR2699406B1 (es)
MX (1) MX9400223A (es)
WO (1) WO1994014425A1 (es)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0705097B2 (en) 1993-06-25 2004-01-14 Alza Corporation Incorporating poly-n-vinyl amide in a transdermal system
FR2745720B1 (fr) * 1996-03-08 1998-05-07 Soc D Pharmacologie Et D Immun Dispositif de diffusion d'un produit volatil dans l'atmosphere
ES2196208T3 (es) * 1996-03-09 2003-12-16 Nitto Denko Corp Preparacion percutanea adhesiva.
CN1219872A (zh) 1996-05-24 1999-06-16 血管技术药物公司 治疗或预防身体通道疾病的组合物和方法
JP4477152B2 (ja) * 1997-05-16 2010-06-09 株式会社共和 ストーマ用又は瘡傷用の皮膚保護材
DE19812688A1 (de) * 1998-03-23 1999-09-30 Basf Ag Verfahren zur Herstellung von festen Dosierungsformen
FR2803204B1 (fr) * 1999-12-30 2002-05-03 Ethymed Lab Dispositif de diffusion d'un produit volatil et procede de preparation
AU3104301A (en) 2000-01-20 2001-07-31 Noven Pharmaceuticals, Inc. Compositions and methods to effect the release profile in the transdermal administration of active agents
DE10025971B4 (de) * 2000-05-25 2004-09-02 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System in Plasterform mit verminderter Tendenz zur Wirkstoffkristallisation und seine Verwendung
DE10025970C2 (de) * 2000-05-25 2002-04-25 Lohmann Therapie Syst Lts Estrogenhaltiges Pflaster mit einem Wirkstoffreservoir auf der Basis von Ethylcellulose und einem Ethylen-Vinylacetat-Vinylpyrrolidon-Copolymer und seine Verwendung
DE60118933T2 (de) * 2000-08-15 2006-11-30 SurModics, Inc., Eden Prairie Matrix zur aufnahme von arzneimitteln
US6479076B2 (en) * 2001-01-12 2002-11-12 Izhak Blank Nicotine delivery compositions
US20060110080A1 (en) * 2002-02-27 2006-05-25 Thomas Toby R Packages and structures with selective dosing of active agent
US20060291756A1 (en) * 2002-02-27 2006-12-28 Thomas Toby R Web materials with active agent for use in forming reclosable packages
US7497623B2 (en) 2002-02-27 2009-03-03 Pactiv Corporation Packages with active agents
US8627828B2 (en) 2003-11-07 2014-01-14 U.S. Smokeless Tobacco Company Llc Tobacco compositions
BRPI0415741B1 (pt) 2003-11-07 2013-07-23 composições de tabaco e métodos de fabricação de uma composição de tabaco
JP5000932B2 (ja) * 2005-06-21 2012-08-15 日東電工株式会社 ニコチン含有経皮吸収製剤
DK2557924T3 (da) 2010-04-13 2019-09-23 Relmada Therapeutics Inc Dermale farmaceutiske sammensætninger af 1-methyl-2',6'-pipecoloxylidid og fremgangsmåde til deres anvendelse
EP2560893B1 (en) * 2010-04-18 2017-10-04 Gevaram Quality Envelopes Ltd. Tamper-resistant envelope
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
RS62297B1 (sr) 2011-11-23 2021-09-30 Therapeuticsmd Inc Prirodne kombinovane hormonske supstitucione formulacije i terapije
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
JP2017516768A (ja) 2014-05-22 2017-06-22 セラピューティックスエムディー インコーポレーテッドＴｈｅｒａｐｅｕｔｉｃｓｍｄ， Ｉｎｃ． 天然の併用ホルモン補充療法剤及び療法
EP3034528B1 (de) 2014-12-19 2017-06-21 Evonik Degussa GmbH Covernetzersysteme für Verkapselungsfolien umfassend Harnstoffverbindungen
EP3034527B1 (de) 2014-12-19 2017-05-31 Evonik Degussa GmbH Covernetzersysteme für Verkapselungsfolien umfassend Bis-(alkenylamid)-Verbindungen
EP3034531A1 (de) * 2014-12-19 2016-06-22 Evonik Degussa GmbH Dispersion zum einfachen Einsatz in der Herstellung von Verkapselungsfolien
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
RU2018133932A (ru) 2016-04-01 2020-05-12 Терапьютиксмд, Инк. Фармацевтическая композиция стероидного гормона
WO2017173044A1 (en) 2016-04-01 2017-10-05 Therapeuticsmd Inc. Steroid hormone compositions in medium chain oils
US11633405B2 (en) 2020-02-07 2023-04-25 Therapeuticsmd, Inc. Steroid hormone pharmaceutical formulations

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2250793B1 (es) * 1973-11-09 1978-12-29 Commissariat Energie Atomique
FR2513243B1 (es) * 1981-09-24 1983-11-18 Commissariat Energie Atomique
US4994267A (en) * 1988-03-04 1991-02-19 Noven Pharmaceuticals, Inc. Transdermal acrylic multipolymer drug delivery system
PT100502A (pt) * 1991-05-20 1993-08-31 Alza Corp Composicoes farmaceuticas para aumentar a capacidade de permeacao na pele utilizando monolinoleato de glicerol

Also Published As

Publication number Publication date
FR2699406B1 (fr) 1995-03-10
ATE172877T1 (de) 1998-11-15
JPH07508291A (ja) 1995-09-14
DK0625901T3 (da) 1999-07-19
EP0625901A1 (fr) 1994-11-30
KR950700729A (ko) 1995-02-20
DE69321945D1 (de) 1998-12-10
WO1994014425A1 (fr) 1994-07-07
DE69321945T2 (de) 1999-04-01
EP0625901B1 (fr) 1998-11-04
KR100314123B1 (ko) 2002-04-24
MX9400223A (es) 1994-07-29
FR2699406A1 (fr) 1994-06-24
US5556635A (en) 1996-09-17
CA2130332A1 (fr) 1994-07-07

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